CCR4 Antibody (205410) [Unconjugated]

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Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD4 APC‑conjugated Monoclonal Antibody (Catalog # FAB3791A) and either (A) Mouse Anti-Human CCR4 Monoclonal Antibody (Catalog ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
205410
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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View Available Formulations

CCR4 Antibody (205410) [Unconjugated] Summary

Additional Information
Clone 205410 was used by HLDA to establish CD designation
Immunogen
Human CCR4 transfectants
Met1-Leu360
Accession # P51679
Specificity
Stains human CCR4-transfected cell lines but not the corresponding parent cell lines. Also detects CCR4 on human PBLs and platelets.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
CCR4
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-reported
  • Flow Cytometry 0.25 ug/10^6 cells
Publications
Read Publications using
MAB1567 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CCR4 Antibody (205410) [Unconjugated]

  • C-C chemokine receptor type 4
  • C-C CKR-4
  • CC-CKR-4HGCN:14099
  • CCR4
  • CCR-4
  • CD194 antigen
  • CD194
  • chemokine (C-C motif) receptor 4
  • chemokine (C-C) receptor 4
  • ChemR13
  • CKR4MGC88293
  • CMKBR4k5-5
  • K5-5

Background

CCR4 is a G protein-linked seven transmembrane domain chemokine receptor that binds the chemokines CCL17/TARC and CCL22/MDC. Current evidence suggests that CCR4 expression is associated with Th-2 type T cells and with platelets. CCR4 expression has also been reported in mature dendritic cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CCR4 Antibody (MAB1567)(19)

We have publications tested in 4 confirmed species: Human, Mouse, Rat, Marmoset.

We have publications tested in 6 applications: CyTof, Flow Cytometry, ICC, IHC, IHC-Fr, Neutralization.


Filter By Application
CyTof
(3)
Flow Cytometry
(12)
ICC
(1)
IHC
(1)
IHC-Fr
(1)
Neutralization
(1)
All Applications
Filter By Species
Human
(16)
Mouse
(1)
Rat
(1)
Marmoset
(1)
All Species
Showing Publications 1 - 10 of 19. Show All 19 Publications.
Publications using MAB1567 Applications Species
MH Nelson, HM Knochelman, SR Bailey, LW Huff, JS Bowers, K Majchrzak-, MM Wyatt, MP Rubinstein, S Mehrotra, MI Nishimura, KE Armeson, PG Giresi, MJ Zilliox, HE Broxmeyer, CM Paulos Identification of human CD4+ T cell populations with distinct antitumor activity Science Advances, 2020-07-01;6(27):. 2020-07-01 [PMID: 32937437] (Flow Cytometry, Human) Flow Cytometry Human
M Martin-Fer, M Bravo Garc, C Gruber, S Murias Loz, MNH Malik, F Alsohime, A Alakeel, R Valdez, S Buta, G Buda, MA Marti, M Larralde, B Boisson, M Feito Rodr, X Qiu, M Chrabieh, M Al Ayed, S Al Muhsen, JV Desai, EMN Ferre, SD Rosenzweig, B Amador-Bor, LY Bravo-Gall, R Olmer, S Merkert, M Bret, AK Sood, A Al-Rabiaah, MH Temsah, R Halwani, M Hernandez, F Pessler, JL Casanova, J Bustamante, MS Lionakis, D Bogunovic Systemic Type I IFN Inflammation in Human ISG15 Deficiency Leads to Necrotizing Skin Lesions Cell Rep, 2020-05-12;31(6):107633. 2020-05-12 [PMID: 32402279] (CyTof, Human) CyTof Human
D Michlmayr, EY Kim, AH Rahman, R Raghunatha, S Kim-Schulz, Y Che, S Kalayci, ZH Gümü?, G Kuan, A Balmaseda, A Kasarskis, SM Wolinsky, M Suaréz-Far, E Harris Comprehensive Immunoprofiling of Pediatric Zika Reveals Key Role for Monocytes in the Acute Phase and No Effect of Prior Dengue Virus Infection Cell Rep, 2020-04-28;31(4):107569. 2020-04-28 [PMID: 32348760] (CyTof, Human) CyTof Human
NM Bath, X Ding, NA Wilson, BM Verhoven, BA Boldt, A Sukhwal, SR Reese, SE Panzer, A Djamali, RR Redfield Desensitization and treatment with APRIL/BLyS blockade in rodent kidney transplant model PLoS ONE, 2019-02-08;14(2):e0211865. 2019-02-08 [PMID: 30735519] (Flow Cytometry, Rat) Flow Cytometry Rat
Evan W Newell Optimization of mass cytometry sample cryopreservation after staining Cytometry A, 2016-10-31;0(0):. 2016-10-31 [PMID: 27798817] (CyTof, Human) CyTof Human
Kap , Yolanda, van Driel , Nikki, Laman , Jon D, Tak , Paul P, 't Hart , Bert A CD20+ B cell depletion alters T cell homing. J Immunol, 2014-04-02;192(9):4242-53. 2014-04-02 [PMID: 24696233] (Flow Cytometry, Marmoset) Flow Cytometry Marmoset
Aruga A, Takeshita N, Kotera Y, Okuyama R, Matsushita N, Ohta T, Takeda K, Yamamoto M Long-term Vaccination with Multiple Peptides Derived from Cancer-Testis Antigens Can Maintain a Specific T-cell Response and Achieve Disease Stability in Advanced Biliary Tract Cancer. Clin Cancer Res, 2013-03-11;19(8):2224-31. 2013-03-11 [PMID: 23479678] (Flow Cytometry, Human) Flow Cytometry Human
Duluc , D, Gannevat , J, Anguiano , E, Zurawski , S, Carley , M, Boreham , M, Stecher , J, Dullaers , M, Banchereau , J, Oh , S Functional diversity of human vaginal APC subsets in directing T-cell responses. Mucosal Immunol, 2012-11-07;6(3):626-38. 2012-11-07 [PMID: 23131784] (Flow Cytometry, Human) Flow Cytometry Human
Pandya AD, Al-Jaderi Z, Hoglund RA, Holmoy T, Harbo HF, Norgauer J, Maghazachi AA Identification of human NK17/NK1 cells. PLoS ONE, 2011-10-21;6(10):e26780. 2011-10-21 [PMID: 22039549] (Flow Cytometry, Human) Flow Cytometry Human
Islam SA, Chang DS, Colvin RA Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells. Nat. Immunol., 2011-01-09;12(2):167-77. 2011-01-09 [PMID: 21217759] (Flow Cytometry, Human) Flow Cytometry Human
Show All 19 Publications.

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Bioinformatics

Gene Symbol CCR4
Uniprot