CCR4 Antibody (205410) [PerCP (Peridinin-chlorophyll Protein Complex)]

Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD3e Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB100F) and either (A) Mouse Anti-Human/Rat CCR4 PerCP-conjugated Monoclonal Antibody (Catalog # FAB1567C) or (B) Mouse IgG2BPerCP Isotype Control (Catalog # IC0041C). View our protocol for Staining Membrane-associated Proteins.

Rat peripheral blood cells were stained with Mouse Anti-Human/Rat CCR4 PerCP-conjugated Monoclonal Antibody (Catalog # FAB1567C, filled histogram) or isotype control antibody (Catalog # IC0041C, open histogram). View our protocol for Staining Membrane-associated Proteins.

• Reactivity: Hu, Rt
• Applications: Flow
• Clone: 205410
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: PerCP (Peridinin-chlorophyll Protein Complex)

CCR4 Antibody (205410) [PerCP (Peridinin-chlorophyll Protein Complex)] Summary

• Immunogen: Human CCR4 transfectants
  Met1-Leu360
  Accession # P51679
• Specificity: Stains human CCR4-transfected cell lines but not the corresponding parent cell lines. Also detects human CCR4 on human PBLs and platelets and rat CCR4 on rat splenocytes.
• Source: N/A
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: CCR4
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.
• Preservative: Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CCR4 Antibody (205410) [PerCP (Peridinin-chlorophyll Protein Complex)]

• C-C chemokine receptor type 4
• C-C CKR-4
• CC-CKR-4HGCN:14099
• CCR4
• CCR-4
• CD194 antigen
• CD194
• chemokine (C-C motif) receptor 4
• chemokine (C-C) receptor 4
• ChemR13
• CKR4MGC88293
• CMKBR4k5-5
• K5-5

Background

CCR4 is a G protein-linked seven transmembrane domain chemokine receptor that binds the chemokines CCL17/TARC and CCL22/MDC. Current evidence suggests that CCR4 expression is associated with Th-2 type T cells and with platelets. CCR4 expression has also been reported in mature dendritic cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CCR4 Antibody (FAB1567C)(1)

Publication using FAB1567C

• T Nargis, K Kumar, AR Ghosh, A Sharma, D Rudra, D Sen, S Chakrabart, S Mukhopadhy, D Ganguly, P Chakrabart KLK5 induces shedding of DPP4 from circulatory Th17 cells in type 2 diabetes Mol Metab, 2017-09-27;6(11):1529-1539. 2017-09-27 [PMID: 29107298] (Flow Cytometry, Human)

Bioinformatics

• Gene Symbol: CCR4
• Uniprot:
  • P51679()