Human CCL22/MDC Quantikine ELISA Kit

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

Order Details

Human CCL22/MDC Quantikine ELISA Kit Summary

Background
The Quantikine Human MDC Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human MDC in cell culture supernates, serum, or plasma. It contains E. coli-expressed recombinant human MDC and has been shown to accurately quantitate the recombinant factor. Results obtained using naturally expressed human MDC showed linear curves that were parallel to the standard curves obta...ined using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally expressed human MDC.
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Specificity
Natural and recombinant human MDC
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
CCL22

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DMD00.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human CCL22/MDC Quantikine ELISA Kit

  • A-152E5.1
  • ABCD-1
  • CC chemokine STCP-1
  • C-C motif chemokine 22
  • CCL22
  • chemokine (C-C motif) ligand 22
  • DC/B-CK
  • Macrophage-derived chemokine
  • MDC
  • MDCStimulated T-cell chemotactic protein 1
  • MGC34554
  • SCYA22MDC(1-69)
  • small inducible cytokine A22
  • small inducible cytokine subfamily A (Cys-Cys), member 22
  • Small-inducible cytokine A22
  • STCP-1
  • stimulated T cell chemotactic protein 1

Background

Macrophage-derived chemokine (MDC), also named stimulated T cell chemotactic protein (STCP-1) and ABCD-1, and now designated as CCL22, is a CC chemokine initially isolated from clones of monocyte-derived macrophages. At the amino acid sequence level, MDC shows less than 35% identity to other CC chemokine family members. Human MDC is expressed in dendritic cells, macrophages and activated monocytes. In addition, MDC expression is detected in thymus, lymph node and appendix tissues. At the amino acid sequence level, mouse and human MDC share 64% identity and 83% similarity.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for CCL22/MDC (DMD00)(26)

We have publications tested in 1 confirmed species: Human.


Filter By Application
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Human
(25)
All Species
Showing Publications 1 - 10 of 26. Show All 26 Publications.
Publications using DMD00 Applications Species
Q Wang, E Schmoeckel, BP Kost, C Kuhn, A Vattai, T Vilsmaier, S Mahner, D Mayr, U Jeschke, HH Heidegger Higher CCL22+ Cell Infiltration is Associated with Poor Prognosis in Cervical Cancer Patients Cancers (Basel), 2019;11(12):. 2019 [PMID: 31842422] (Human) Human
D Bao, J Zhao, X Zhou, Q Yang, Y Chen, J Zhu, P Yuan, J Yang, T Qin, S Wan, J Xing Mitochondrial fission-induced mtDNA stress promotes tumor-associated macrophage infiltration and HCC progression Oncogene, 2019;0(0):. 2019 [PMID: 30894684] (Human) Human
TD Jung, SI Choi, SH Choi, BY Cho, WS Sim,, SJ Lee, SJ Park, DB Kim, YC Kim, JH Lee, OH Lee Changes in the Anti-Allergic Activities of Sesame by Bioconversion Nutrients, 2018;10(2):. 2018 [PMID: 29443928] (Human) Human
MR Pranzatell, ED Tate, TJ Allison Case-control, exploratory study of cerebrospinal fluid chemokines/cytokines and lymphocyte subsets in childhood Tourette syndrome with positive streptococcal markers Cytokine, 2017;96(0):49-53. 2017 [PMID: 28288328] (Human) Human
Zhang W, Zheng X, DU L, Sun J, Shen Z, Shi C, Sun S, Zhang Z, Chen X, Qin M, Liu X, Tao J, Jia L, Fan H, Zhou B, Yu Y, Ying H, Hui L, Liu X, Yi X, Liu X, Zhang L, Duan S High salt primes a specific activation state of macrophages, M(Na). Cell Res, 2015;25(8):893-910. 2015 [PMID: 26206316] (Human) Human
Shi G, Han J, Liu G, Hao Y, Ma Y, Li T, Wu X, Zhang H, Liu Y, Wang B, Kong Y, Zhou J, Zeng H Expansion of activated regulatory T cells by myeloid-specific chemokines via an alternative pathway in CSF of bacterial meningitis patients. Eur J Immunol, 2014;44(2):420-30. 2014 [PMID: 24155161] (Human) Human
Pranzatelli, Michael, Tate, Elizabet, McGee, Nathan R, Travelstead, Anna L, Colliver, Jerry A, Ness, Jayne M, Ransohoff, Richard BAFF/APRIL system in pediatric OMS: relation to severity, neuroinflammation, and immunotherapy. J Neuroinflammation, 2013;10(0):10. 2013 [PMID: 23324534] (Human) Human
Rai AK, Thakur CP, Singh A Regulatory T cells suppress T cell activation at the pathologic site of human visceral leishmaniasis. PLoS ONE, 2012;7(2):e31551. 2012 [PMID: 22347492] (Human) Human
Watanabe T, Asano N, Fichtner-Feigl S, Gorelick PL, Tsuji Y, Matsumoto Y, Chiba T, Fuss IJ, Kitani A, Strober W NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway. J. Clin. Invest., 2010;120(5):1645-62. 2010 [PMID: 20389019] (Human) Human
Oo YH, Weston CJ, Lalor PF, Curbishley SM, Withers DR, Reynolds GM, Shetty S, Harki J, Shaw JC, Eksteen B, Hubscher SG, Walker LS, Adams DH Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. J. Immunol., 2010;184(6):2886-98. 2010 [PMID: 20164417]
Show All 26 Publications.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for CCL22/MDC (DMD00). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

HRP DMD00

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Bioinformatics Tool for CCL22/MDC (DMD00)

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Blogs on CCL22/MDC.

Signal Transducer and Activator of Transcription STAT6: More than a Player in Allergic Inflammation
By Jamshed Arslan, Pharm. D., PhD. What is STAT6?The cellular pathway comprising tyrosine kinase Janus Kinase (JAK) and the transcription factor STAT connect extracellular signals from various cytokines, hormones an...  Read full blog post.

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Bioinformatics

Gene Symbol CCL22