CCR1 Antibody

Images

 
Immunohistochemistry-Paraffin: CCR1 Antibody [NLS1242] - Anti-CCR1 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: CCR1 Antibody [NLS1242] - Analysis of anti-CCR1 antibody with human spleen, lymphocytes.
Immunohistochemistry-Paraffin: CCR1 Antibody [NLS1242] - Analysis of anti-CCR1 antibody with human colon, carcinoma.
Immunohistochemistry-Paraffin: CCR1 Antibody [NLS1242] - Anti-CCR1 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Product Details

Summary
Reactivity Hu, BvSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

CCR1 Antibody Summary

Immunogen
Synthetic 20 amino acid peptide from 2nd extracellular domain of human CCR1.
Localization
Plasma membrane
Specificity
Human CCR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Bovine (95%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CCR1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5 ug/ml
Control
CCR1 Overexpression Lysate
CCR1 Knockout A549 Cell Lysate

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (95%), Mouse (85%), Marmoset (80%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CCR1 Antibody

  • C-C chemokine receptor type 1
  • CC-CKR-1
  • CCR1
  • CCR-1
  • CD191 antigen
  • CD191
  • chemokine (C-C motif) receptor 1
  • CKR1
  • CKR-1
  • CMKBR1SCYAR1
  • CMKR1
  • HM145C-C CKR-1
  • LD78 receptor
  • Macrophage inflammatory protein 1-alpha receptor
  • MIP-1alpha-R
  • MIP1aR
  • RANTES receptor
  • RANTES-R

Background

CCR1, a Chemokine Receptor, affects stem cell proliferation and mediates systemic inflammatory responses. This receptor is stimulated by the beta chemokines RANTES, MCP-1, and MIP-1 alpha. Disruption of CCR1 enhances protection from pulmonary inflammation and reduces the development of respiratory distress syndrome in rat. CCR1 is widely expressed, particularly in hematopoietic cells from blood, vessels, and bone marrow. This receptor has also been reported to be expressed in lung, brain, placenta, heart, skeletal muscle, and kidney. ESTs have been isolated from blood, kidney, liver/spleen, lung, placenta, uterus, and vessel libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Other Available Formats

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Bioinformatics Tool for CCR1 Antibody (NLS1242)

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Blogs on CCR1.

CCR1 (C-C chemokine receptor type 1)
Chemokines play a central role in inflammation and are crucial for recruitment of immune cells to sites of infection. The chemokine-dependent activation of leukocytes occurs through binding to G-protein coupled receptors. These chemokine receptor s...  Read full blog post.

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Contact Information

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Calculators

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Bioinformatics

Gene Symbol CCR1
Entrez