Mouse CCL11/Eotaxin Quantikine ELISA Kit, 2 Plate



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Applications ELISA

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Mouse CCL11/Eotaxin Quantikine ELISA Kit, 2 Plate Summary

The Quantikine Mouse Eotaxin Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse Eotaxin in cell culture supernates, serum, and plasma. It contains recombinant mouse Eotaxin and antibodies raised against the recombinant protein. This immunoassay has been shown to quantitate the recombinant protein accurately. Results obtained using natural mouse Eotaxin showed dose curves t...hat were parallel to the standard curves obtained using the E. coli-expressed kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse Eotaxin.
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Natural and recombinant mouse Eotaxin.  This assay cross-reacts 0.062% with Human Eotaxin and recognizes Rat Eotaxin.
Assay Type
Solid Phase Sandwich ELISA
See PDF Datasheet for details
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details


Application Notes
No significant interference observed with available related molecules.
Read Publications using MME00.

Packaging, Storage & Formulations

Store the unopened product at 2 - 8 °C. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse CCL11/Eotaxin Quantikine ELISA Kit, 2 Plate

  • C-C motif chemokine 11
  • CCL11
  • chemokine (C-C motif) ligand 11
  • Eosinophil chemotactic protein
  • Eotaxin
  • eotaxin-1
  • MGC22554
  • SCYA11Small-inducible cytokine A11
  • small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)


CCL11/Eotaxin is a chemokine that interacts with CCR3 to induce eosinophil, basophil, dendritic cell, and Th2 cell chemoattraction during inflammatory and allergic reactions. Its production is upregulated in airway epithelium, alveolar macrophages, eosinophils, smooth muscle cells, chondrocytes, and fibroblasts following allergen or inflammatory challenge. CCL11 is also involved in the growth of myeloid cell progenitors and the differentiation of mast cells.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to

Publications for CCL11/Eotaxin (MME00)(50)

We have publications tested in 2 confirmed species: Mouse, Rat.

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Publications using MME00 Applications Species
R Wang, K Huang CCL11 increases the proportion of CD4+CD25+Foxp3+ Treg cells and the production of IL?2 and TGF?&beta by CD4+ T�cells via the STAT5 signaling pathway Mol Med Rep, 2020;0(0):. 2020 [PMID: 32323817] (Mouse) Mouse
I Sulaiman, K Tan, N Mohtarrudi, JC Woei Lim, J Stanslas Andrographolide prevented toluene diisocyanate-induced occupational asthma and aberrant airway E-cadherin distribution via p38 MAPK-dependent Nrf2 induction Pulm Pharmacol Ther, 2018;0(0):. 2018 [PMID: 30244166] (Mouse) Mouse
A Aguilar-Va, N Haji, D De Gregori, E Matta-Cama, MJ Eslamizade, J Popic, V Sharma, R Cao, C Rummel, A Tanti, S Wiebe, N Nuñez, S Comai, R Nadon, G Luheshi, N Mechawar, G Turecki, JC Lacaille, G Gobbi, N Sonenberg Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E Nat Commun, 2018;9(1):2459. 2018 [PMID: 29941989] (Mouse) Mouse
Macrophages and cardiac fibroblasts are the main producers of eotaxins and regulate eosinophil trafficking to the heart Eur J Immunol, 2016;0(0):. 2016 [PMID: 27621211] (Mouse) Mouse
Increased mitochondrial arginine metabolism supports bioenergetics in asthma J Clin Invest, 2016;0(0):. 2016 [PMID: 27214549] (Mouse) Mouse
Itoga M, Konno Y, Moritoki Y, Saito Y, Ito W, Tamaki M, Kobayashi Y, Kayaba H, Kikuchi Y, Chihara J, Takeda M, Ueki S, Hirokawa M G-protein-coupled estrogen receptor agonist suppresses airway inflammation in a mouse model of asthma through IL-10. PLoS ONE, 2015;10(3):e0123210. 2015 [PMID: 25826377] (Mouse) Mouse
Erickson, Michelle, Morofuji, Yoichi, Owen, Joshua B, Banks, William Rapid transport of CCL11 across the blood-brain barrier: regional variation and importance of blood cells. J Pharmacol Exp Ther, 2014;349(3):497-507. 2014 [PMID: 24706984] (Mouse) Mouse
Johnson T, Rangel D, Graham B, Brough D, Gall J Genetic vaccine for respiratory syncytial virus provides protection without disease potentiation. Mol Ther, 2014;22(1):196-205. 2014 [PMID: 23752342] (Mouse) Mouse
Cho SH, Oh SY, Zhu Z, Lee J, Lane AP Spontaneous eosinophilic nasal inflammation in a genetically-mutant mouse: comparative study with an allergic inflammation model. PLoS ONE, 2012;7(4):e35114. 2012 [PMID: 22509389] (Mouse) Mouse
Barlow JL, Flynn RJ, Ballantyne SJ, McKenzie AN Reciprocal expression of IL-25 and IL-17A is important for allergic airways hyperreactivity. Clin. Exp. Allergy, 2011;41(10):1447-55. 2011 [PMID: 21722219] (Mouse) Mouse
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Product General Protocols

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FAQs for CCL11/Eotaxin (MME00). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

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Blogs on CCL11/Eotaxin.

Signal Transducer and Activator of Transcription STAT6: More than a Player in Allergic Inflammation
By Jamshed Arslan, Pharm. D., PhD. What is STAT6?The cellular pathway comprising tyrosine kinase Janus Kinase (JAK) and the transcription factor STAT connect extracellular signals from various cytokines, hormones an...  Read full blog post.

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Gene Symbol Ccl11