Mouse CCL3/MIP-1 alpha Quantikine ELISA Kit, 2 Plate

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Mouse CCL3/MIP-1 alpha Quantikine ELISA Kit, 2 Plate Summary

Background
The Quantikine Mouse MIP-1 alpha Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse MIP-1 alpha levels in cell culture supernates and serum. It contains E. coli-expressed recombinant mouse MIP-1 alpha and antibodies raised against the recombinant protein. Results obtained for naturally occurring mouse MIP-1 alpha showed linear curves that were parallel to the stan...dard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values of natural mouse MIP-1 alpha.
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Specificity
Natural and recombinant mouse MIP-1 alpha
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
CCL3

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using
MMA00 in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse CCL3/MIP-1 alpha Quantikine ELISA Kit, 2 Plate

  • C-C motif chemokine 3
  • MIP1-(a)
  • AI323804
  • CCL3
  • chemokine (C-C motif) ligand 3
  • G0S19-1
  • LD78a
  • LD78alpha
  • MIP1 alpha
  • MIP-1 alpha
  • MIP1A
  • MIP-1alpha
  • MIP1-alpha
  • PAT 464.1
  • SCYA3
  • SIS-beta

Background

MIP-1 alpha (macrophage inflammatory protein 1 alpha) is a member of the CC or beta chemokine subfamily that was originally purified from the conditioned media of an LPS-stimulated murine macrophage cell line. MIP-1 alpha acts as a chemoattractant to a variety of cells including monocytes, T cells, B cells and eosinophils.

The two human MIP-1 alpha genes arise by duplication/mutation. They code for MIP-1 alpha isoforms CCL3/LD78a and CCL3L1/LD78b, which share 94% amino acid sequence homology. Whereas the human CCL3/LD78a is a single-copy gene, the human CCL3L1/LD78b gene copy number varies within the population. Human CCL3L1/LD78b binds and signals through chemokine receptors CCR1, CCR5. When compared to CCL3/LD78a, CCL3L1/LD78b has higher binding affinity to CCR5, which also functions as a coreceptor for HIV-1 entry. The copy number of CCL3L1 is one of several genetic determinants of HIV-1 susceptibility.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for CCL3/MIP-1 alpha (MMA00)(68)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: ELISA Capture.


Filter By Application
ELISA Capture
(1)
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Mouse
(68)
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Showing Publications 1 - 10 of 68. Show All 68 Publications.
Publications using MMA00 Applications Species
K Taniguchi, Y Ando, H Nobori, S Toba, T Noshi, M Kobayashi, M Kawai, R Yoshida, A Sato, T Shishido, A Naito, K Matsuno, M Okamatsu, Y Sakoda, H Kida Inhibition of avian-origin influenza A(H7N9) virus by the novel cap-dependent endonuclease inhibitor baloxavir marboxil Sci Rep, 2019;9(1):3466. 2019 [PMID: 30837531] (Mouse) Mouse
N Simon, A Antignani, SM Hewitt, M Gadina, C Alewine, D FitzGerald Tofacitinib enhances delivery of antibody-based therapeutics to tumor cells through modulation of inflammatory cells JCI Insight, 2019;0(0):. 2019 [PMID: 30720466] (Mouse) Mouse
N Guo, V DeAngelis, C Zhu, EH Schuchman, CM Simonaro Pentosan Polysulfate Treatment of Mucopolysaccharidosis Type IIIA Mice JIMD Rep, 2018;0(0):. 2018 [PMID: 29654542] (Mouse) Mouse
F Allen, ID Bobanga, P Rauhe, D Barkauskas, N Teich, C Tong, J Myers, AY Huang CCL3 augments tumor rejection and enhances CD8+T cell infiltration through NK and CD103+dendritic cell recruitment via IFN? Oncoimmunology, 2018;7(3):e1393598. 2018 [PMID: 29399390] (ELISA Capture, Mouse) ELISA Capture Mouse
S Piñeiro-He, E Alfaro-Arn, JA Gregory, R Torrens, C Ruíz-Martí, M Adner, IP López, JG Pichel Characterization of the acute inflammatory profile and resolution of airway inflammation after Igf1r-gene targeting in a murine model of HDM-induced asthma PLoS ONE, 2017;12(12):e0190159. 2017 [PMID: 29272313] (Mouse) Mouse
MKB Prado, GA Locachevic, KF Zoccal, FWG Paula-Silv, C Fontanari, JC Ferreira, PAT Pereira, LG Gardinassi, SG Ramos, CA Sorgi, ALC Darini, LH Faccioli Leukotriene B4 is essential for lung host defence and alpha-defensin-1 production during Achromobacter xylosoxidans infection Sci Rep, 2017;7(1):17658. 2017 [PMID: 29247243] (Mouse) Mouse
L Szulc-D?br, J Struzik, A Ostrowska, M Guzera, FN Toka, M Bossowska-, MM Giery?ska, A Winnicka, Z Nowak, MG Niemia?tow Functional paralysis of GM-CSF-derived bone marrow cells productively infected with ectromelia virus PLoS ONE, 2017;12(6):e0179166. 2017 [PMID: 28604814] (Mouse) Mouse
S Sanges, M Jendoubi, N Kavian, C Hauspie, S Speca, JC Crave, T Guerrier, G Lefèvre, V Sobanski, A Savina, E Hachulla, PY Hatron, M Labalette, F Batteux, S Dubucquoi, D Launay B Cell Homeostasis and Functional Properties Are Altered in an Hypochlorous Acid-Induced Murine Model of Systemic Sclerosis Front Immunol, 2017;8(0):53. 2017 [PMID: 28223983] (Mouse) Mouse
Activation of the cholinergic anti-inflammatory system by nicotine attenuates arthritis via suppression of macrophage migration Mol Med Rep, 2016;14(6):5057-5064. 2016 [PMID: 27840928] (Mouse) Mouse
LRBA is Essential for Allogeneic Responses in Bone Marrow Transplantation Sci Rep, 2016;6(0):36568. 2016 [PMID: 27824136] (Mouse) Mouse
Show All 68 Publications.

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FAQs for CCL3/MIP-1 alpha (MMA00). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

HRP MMA00
HRP MMA00
HRP MMA00

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Bioinformatics

Gene Symbol CCL3