CXCR1/IL-8RA Antibody (42705) [Unconjugated]


Human peripheral blood granulocytes were stained with Mouse Anti-HumanCXCR1/IL‑8 RA Monoclonal Antibody (Catalog # MAB330, filled histogram) or isotype control antibody (Catalog # MAB003, open histogram), more
CXCR1/IL‑8 RA was detected in immersion fixed paraffin-embedded sections of human endometrial cancer tissue using Mouse Anti-Human CXCR1/IL‑8 RA Monoclonal Antibody (Catalog # MAB330) at 5 µg/mL overnight at 4 °C. more
CXCR1/IL‑8 RA was detected in immersion fixed frozen sections of human lymph nodes using Mouse Anti-Human CXCR1/IL‑8 RA Monoclonal Antibody (Catalog # MAB330) at 15 µg/mL overnight at 4 °C. Tissue was stained more
Recombinant Human CXCL8/IL‑8 (Catalog # 208-IL) chemoattracts the BaF3 mouse pro‑B cell line transfected with human CXCR1 in a dose-dependent manner (orange line). The amount of cells that migrated through to the more

Product Details

Reactivity HuSpecies Glossary
Applications Flow, IHC, B/N, CyTOF-reported

Order Details

CXCR1/IL-8RA Antibody (42705) [Unconjugated] Summary

Additional Information
Clone 42705 was used by HLDA to establish CD designation
NS0 mouse myeloma cell line transfected with human CXCR1/IL-8 RA
Accession # AAA59159
Detects human CXCR1/IL-8 RA transfectants but not the parental cell line. It does not cross-react with human CXCR2.
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Endotoxin Note
<0.10 EU per 1 μg of the antibody by the LAL method.
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • CyTOF-reported
  • Flow Cytometry 0.25 ug/10^6 cells
  • Immunohistochemistry 8-25 ug/mL
  • Neutralization 0.4-2.0 ug/mL
Read Publications using
MAB330 in the following applications:

Packaging, Storage & Formulations

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CXCR1/IL-8RA Antibody (42705) [Unconjugated]

  • CD128
  • CD181 antigen
  • CD181
  • CDw128aC-C
  • chemokine (C-X-C motif) receptor 1
  • CKR-1
  • CMKAR1
  • C-X-C chemokine receptor type 1
  • CXCR1
  • CXC-R1
  • CXCR-1
  • High affinity interleukin-8 receptor A
  • IL-8 RA
  • IL-8 receptor type 1
  • IL-8R A
  • IL8R1
  • IL8RA
  • IL8RAC-C-CKR-1
  • IL8RBA
  • interleukin 8 receptor, alpha
  • interleukin-8 receptor type 1
  • interleukin-8 receptor type A


The human C-X-C chemokine IL-8 is a potent neutrophil chemotactic and activating factor. Two distinct G protein-linked cell surface receptors, known as IL-8 RA (type I or CXCR1) and IL-8 RB (type II or CXCR2), can interact with the IL-8 molecule. These two receptors share 77% amino acid homology. CXCR1 expression has been documented on neutrophils, monocytes, and a small population of T cells.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu
Applications: CyTOF-ready, ELISA(Cap), ELISA(Det), ELISA(Sta), ICC, ICFlow, Neut, Simple Western, WB
Species: Hu
Applications: CyTOF-ready, Flow, IHC, Neut
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: CyTOF-ready, Flow, ICC, Neut
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P, WB
Species: Mu
Applications: ELISA
Species: Hu
Applications: CyTOF-ready, Flow, IHC, Neut
Species: Hu
Applications: CyTOF-ready, Flow
Species: Mu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu, Mu
Applications: Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
Species: Hu
Applications: CyTOF-ready, Flow, IHC, Neut
Species: Hu
Applications: BA
Species: Hu
Applications: CyTOF-ready, Flow, IHC, Neut
Species: Hu
Applications: CyTOF-ready, ELISA, Flow, ICC/IF, IHC, IHC-P, PA, WB
Species: Hu
Applications: BA
Species: Hu
Applications: ELISA
Species: Hu
Applications: Flow, IHC, B/N, CyTOF-reported

Publications for CXCR1/IL-8RA Antibody (MAB330)(39)

We have publications tested in 4 confirmed species: Human, Mouse, Rat, Guinea Pig.

We have publications tested in 10 applications: Bioassay, Flow Cytometry, Functional Assay, ICC, IHC, IHC-Fr, IHC-P, In Vivo, Neutralization, Western Blot.

Filter By Application
Flow Cytometry
Functional Assay
In Vivo
Western Blot
All Applications
Filter By Species
Guinea Pig
All Species
Showing Publications 1 - 10 of 39. Show All 39 Publications.
Publications using MAB330 Applications Species
SK Sarvestani, S Signs, B Hu, Y Yeu, H Feng, Y Ni, DR Hill, RC Fisher, S Ferrandon, RK DeHaan, J Stiene, M Cruise, TH Hwang, X Shen, JR Spence, EH Huang Induced organoids derived from patients with ulcerative colitis recapitulate colitic reactivity Nature Communications, 2021;12(1):262. 2021-01-01 [PMID: 33431859] (IHC, Human) IHC Human
PC Hart, HA Kenny, N Grassl, KM Watters, LM Litchfield, F Coscia, I Blaženovi?, L Ploetzky, O Fiehn, M Mann, E Lengyel, IL Romero Mesothelial Cell HIF1alpha Expression Is Metabolically Downregulated by Metformin to Prevent Oncogenic Tumor-Stromal Crosstalk Cell Rep, 2019;29(12):4086-4098.e6. 2019-01-01 [PMID: 31851935] (Neutralization, Mouse) Neutralization Mouse
AJ Hoogendijk, F Pourfarzad, CEM Aarts, ATJ Tool, IH Hiemstra, L Grassi, M Frontini, AB Meijer, M van den Bi, TW Kuijpers Dynamic Transcriptome-Proteome Correlation Networks Reveal Human Myeloid Differentiation and Neutrophil-Specific Programming Cell Rep, 2019;29(8):2505-2519.e4. 2019-01-01 [PMID: 31747616] (Flow Cytometry, Human) Flow Cytometry Human
F Caccuri, A Bugatti, S Corbellini, S Roversi, A Zani, P Mazzuca, S Marsico, A Caruso, C Giagulli The Synthetic Dipeptide Pidotimod Shows a Chemokine-Like Activity through CXC Chemokine Receptor 3 (CXCR3) Int J Mol Sci, 2019;20(21):. 2019-01-01 [PMID: 31653015] (Neutralization, Human) Neutralization Human
I Sharma, A Singh, F Siraj, S Saxena IL-8/CXCR1/2 signalling promotes tumor cell proliferation, invasion and vascular mimicry in glioblastoma J. Biomed. Sci., 2018;25(1):62. 2018-01-01 [PMID: 30086759] (Bioassay, Human) Bioassay Human
CH Hung, FM Chen, YC Lin, ML Tsai, SL Wang, YC Chen, YT Chen, MF Hou Altered monocyte differentiation and macrophage polarization patterns in patients with breast cancer BMC Cancer, 2018;18(1):366. 2018-01-01 [PMID: 29614988] (Flow Cytometry, Human) Flow Cytometry Human
P Mazzuca, S Marsico, K Schulze, S Mitola, MC Pils, C Giagulli, CA Guzman, A Caruso, F Caccuri Role of autophagy in the HIV-1 matrix protein p17-driven lymphangiogenesis J. Virol., 2017;0(0):. 2017-01-01 [PMID: 28592537] (Neutralization, Human) Neutralization Human
ALT Loi, S Hoonhorst, C van Aalst, J Langereis, V Kamp, S Sluis-Eisi, N Ten Hacken, JW Lammers, L Koenderman Proteomic profiling of peripheral blood neutrophils identifies two inflammatory phenotypes in stable COPD patients Respir. Res., 2017;18(1):100. 2017-01-01 [PMID: 28532454] (Flow Cytometry, Human) Flow Cytometry Human
Nader Alaridah Mycobacteria Manipulate G-Protein-Coupled Receptors to Increase Mucosal Rac1 Expression in the Lungs J Innate Immun, 2016;0(0):. 2016-01-01 [PMID: 28013312] (Neutralization, Mouse) Neutralization Mouse
Chen , Lianyu, Fan , Jie, Chen , Hao, Meng , Zhiqiang, Chen , Zhen, Wang , Peng, Liu , Luming The IL-8/CXCR1 axis is associated with cancer stem cell-like properties and correlates with clinical prognosis in human pancreatic cancer cases. Sci Rep, 2014;4(0):5911. 2014-01-01 [PMID: 25081383] (Neutralization, Human) Neutralization Human
Show All 39 Publications.

Reviews for CXCR1/IL-8RA Antibody (MAB330) (0)

There are no reviews for CXCR1/IL-8RA Antibody (MAB330). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for CXCR1/IL-8RA Antibody (MAB330) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies


Isotype Controls

Additional CXCR1/IL-8RA Products

Bioinformatics Tool for CXCR1/IL-8RA Antibody (MAB330)

Discover related pathways, diseases and genes to CXCR1/IL-8RA Antibody (MAB330). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for CXCR1/IL-8RA Antibody (MAB330)

Discover more about diseases related to CXCR1/IL-8RA Antibody (MAB330).

Pathways for CXCR1/IL-8RA Antibody (MAB330)

View related products by pathway.

PTMs for CXCR1/IL-8RA Antibody (MAB330)

Learn more about PTMs related to CXCR1/IL-8RA Antibody (MAB330).

Blogs on CXCR1/IL-8RA

There are no specific blogs for CXCR1/IL-8RA, but you can read our latest blog posts.
Download our IHC Handbook

Customers Who Bought This Also Bought

Contact Information

Product PDFs


Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.


Review this Product

Be the first to review our CXCR1/IL-8RA Antibody (42705) [Unconjugated] and receive a gift card or discount.


Gene Symbol CXCR1