BMP-2 Antibody


Western Blot: BMP-2 Antibody [NBP1-19751] - Extracts from HUVEC cells.
Immunohistochemistry: BMP-2 Antibody [NBP1-19751] - Analysis of BMP2 in mouse heart using DAB with hematoxylin counterstain.
Immunohistochemistry-Paraffin: BMP-2 Antibody [NBP1-19751] - Paraffin-embedded human heart tissue.

Product Details

Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC, IHC-P
1.15 mg/ml

BMP-2 Antibody Summary

A synthetic peptide made to an internal region of human BMP2 (within residues 250-350) [Swiss-Prot# P12643]
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS, pH 7.4
0.05% Sodium Azide
1.15 mg/ml
Immunogen affinity purified


  • Western Blot 0.5 ug/ml
  • Immunohistochemistry 1:50-1:200
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
This BMP2 antibody is useful for Immunohistochemistry-Paraffin and Western Blot, where a band is seen ~44 kDa. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
44 kDa
Read Publications using
NBP1-19751 in the following applications:

  • EM
    1 publication
  • IHC
    1 publication
  • 3 publications
  • WB
    2 publications

Reactivity Notes

Human, mouse and rat.

Alternate Names for BMP-2 Antibody

  • BMP2
  • BMP-2
  • BMP-2A
  • BMP2ABone morphogenetic protein 2A
  • bone morphogenetic protein 2


Bone morphogenic protein 2 is required for effective healing of fractures in bone. It is necessary for the expression of transcription factors that regulate osteogenesis and differentiation of progenitor cells into mature osteoblasts. Embryologically, BMP2 is important in mesenchymal maturation to fetal valves. The same mechanism of maturation is also utilized by tumor molecular machinery once mesenchymal stem cells are recruited to tumor microenvironments, leading to many recent attempts to generate BMP inhibitors in the treatment of ovarian and colon cancer. The activity of BMP2 is antagonized by the activity of Bambi and Crim1. BMP2 is an interesting target for distinguishing the mechanism by which normal and necessary maturation processes are mutated in tumorigenesis.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for BMP-2 Antibody (NBP1-19751)(7)

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 4 applications: EM, IHC, IHC-P, WB.

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Showing Publications 1 - 7 of 7.
Publications using NBP1-19751 Applications Species
Chen H, Choesang T, Li H et al. Increased hepcidin in transferrin-treated thalassemic mice correlates with increased liver BMP2 expression and decreased hepatocyte ERK activation. Haematologica. 2015 Dec 03 [PMID:26635037] (WB, Mouse) WB Mouse
Gullard A, Croney CM, Wu X et al. Reduced Dentin Matrix Protein Expression in Camurati-Engelmann Disease Transgenic Mouse Model. J Cell Physiol 2016 May [PMID:26427011] (Mouse) Mouse
Scimeca M, Bonanno E, Piccirilli E et al. Satellite Cells CD44 Positive Drive Muscle Regeneration in Osteoarthritis Patients. Stem Cells Int 2015 [PMID:26101529] (IHC) IHC
Bridgewater LC, Mayo JL, Evanson BG et al. A Novel Bone Morphogenetic Protein 2 Mutant Mouse, nBmp2NLStm), Displays Impaired Intracellular Ca2+) Handling in Skeletal Muscle. Biomed Res Int 2013 [PMID:24369527] (Mouse) Mouse
Bridgewater LC, Mayo JL, Evanson BG et al. A Novel Bone Morphogenetic Protein 2 Mutant Mouse, nBmp2NLStm), Displays Impaired Intracellular Ca2+) Handling in Skeletal Muscle. Biomed Res Int 2013 [PMID:24369527] (IHC-P, Mouse) IHC-P Mouse
Yeom M, Kim SH, Lee B et al. Effects of Laser Acupuncture on Longitudinal Bone Growth in Adolescent Rats. Evid Based Complement Alternat Med. 2013 [PMID:23986782] (IHC-P, Rat) IHC-P Rat
Scimeca M, Bonanno E, Piccirilli E, Baldi J. Satellite Cells CD44 Positive Drive Muscle Regeneration in Osteoarthritis Patients. Stem Cells International. 2015 (IHC-P, WB, EM, Human) IHC-P, WB, EM Human

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Product General Protocols

View specific protocols for BMP-2 Antibody (NBP1-19751): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for BMP-2 Antibody (NBP1-19751). (Showing 1 - 2 of 2 FAQs).

  1. I am interested in Bone Morphogenic Protein 2 (BMP-2) for clinical trial in humans. I am using this protein in stem cells culture for future use in humans. Do you have BMP-2 in pharma grade that I can use for humans?
    • Our antibodies are for research purposes only unfortunately. I am sorry we cannot be of further help.
  2. We onced ordered an anti BMP2 antibody (NBP1-19751) from your company, and have gotten great WB results. Your product has been included in our manuscript. Now reviewers are asking about the cross activity of this antibody with other BMPs, such as BMP6 or BMP9. Did you ever check the cross-react of the BMP2 antibody?
    • Unfortunately, we have not tested this antibody against other/recombinant BMPs so far but I can assure you that it will not be expected to react with any other BMPs. NBP1-19751 was generated against an immunogen peptide from AA250-350 of BMP2 protein [Swiss-Prot# P12643], and this sequence does not show any sequence similarity/homology with any other BMPs.

Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor (R) 405 Labeled NBP1-19751AF405
Alexa Fluor (R) 488 Labeled NBP1-19751AF488
Alexa Fluor (R) 647 Labeled NBP1-19751AF647
Alexa Fluor (R) 700 Labeled NBP1-19751AF700
Biotin Labeled NBP1-19751B
DyLight 405 Labeled NBP1-19751V
DyLight 488 Labeled NBP1-19751G
DyLight 550 Labeled NBP1-19751R
DyLight 650 Labeled NBP1-19751C
FITC Labeled NBP1-19751F
HRP Labeled NBP1-19751H

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Contact Information

Product PDFs


Gene Symbol BMP2

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