Abhd5 Antibody [Biotin]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Biotin

Abhd5 Antibody [Biotin] Summary

• Immunogen: A synthetic peptide made to an internal region within residues 200-300 of the human Abhd5 protein. [Swiss-Prot# Q8WTS1]
• Localization: Cytoplasm. Colocalizatd with PLIN and ADRP on the surface of lipid droplets. The localization is dependant upon the metabolic status of the adipocytes and the activity of PKA.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ABHD5
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: This Abhd5 antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot analysis, where a band is seen at ~43 kDa. In ICC/IF cytoplasmic staining was observed in Hela cells.
• Readout System:
  • Streptavidin Native Protein NBP2-29367
  • Streptavidin Native Protein NBP2-29370
  • Streptavidin Native Protein NBP2-29371

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID:23878361)

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: IgG purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Abhd5 Antibody [Biotin]

• abhydrolase domain containing 5
• Abhydrolase domain-containing protein 5,1-acylglycerol-3-phosphate O-acyltransferase ABHD5
• CDS
• CGI58
• EC 2.3.1.51
• IECN2
• Lipid droplet-binding protein CGI-58
• MGC8731
• NCIE2CGI-58

Background

The CGI58 protein belongs to a large family of proteins characterized by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in this gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation. Widely expressed in various tissues, including skin, lymphocytes, liver, skeletal muscle and brain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ABHD5