Abhd5 Antibody [HRP]

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB110-41576H
    • Availability
      Product Discontinued

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Abhd5 Antibody [HRP] Summary

Immunogen
A synthetic peptide made to an internal region within residues 200-300 of the human Abhd5 protein. [Swiss-Prot# Q8WTS1]
Localization
Cytoplasm. Colocalizatd with PLIN and ADRP on the surface of lipid droplets. The localization is dependant upon the metabolic status of the adipocytes and the activity of PKA.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ABHD5
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
This Abhd5 antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot analysis, where a band is seen at ~43 kDa. In ICC/IF cytoplasmic staining was observed in Hela cells.
Readout System

Reactivity Notes

Human and rat. Mouse reactivity reported in scientific literature (PMID:23878361)

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
IgG purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Abhd5 Antibody [HRP]

  • abhydrolase domain containing 5
  • Abhydrolase domain-containing protein 5,1-acylglycerol-3-phosphate O-acyltransferase ABHD5
  • CDS
  • CGI58
  • EC 2.3.1.51
  • IECN2
  • Lipid droplet-binding protein CGI-58
  • MGC8731
  • NCIE2CGI-58

Background

The CGI58 protein belongs to a large family of proteins characterized by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in this gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation. Widely expressed in various tissues, including skin, lymphocytes, liver, skeletal muscle and brain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Bioinformatics

Gene Symbol ABHD5