OXPAT Antibody - BSA Free


Western Blot: OXPAT Antibody [NB110-60509] - Detection of OXPAT in human (lane 1) and mouse (lane 2) heart lysate.
Immunohistochemistry: OXPAT Antibody [NB110-60509] - Staining of OXPAT in paraffin embedded mouse fat.
Simple Western: OXPAT Antibody [NB110-60509] - Simple Western lane view shows a specific band for OXPAT in 0.5 mg/ml of Human Heart (left) and Mouse Heart (right) lysate. This experiment was performed under reducing ...read more

Product Details

Reactivity Hu, Mu, Po, Bv, ShSpecies Glossary
Applications WB, Simple Western, ICC/IF, IHC, IHC-Fr, IHC-P
BSA Free
1.0 mg/ml

Order Details

OXPAT Antibody - BSA Free Summary

A synthetic peptide made to a region of the human OXPAT protein, within residues 300-400. [UniProt# Q00G26]
Predicted Species
Sheep (94%). Backed by our 100% Guarantee.
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry 1.0-5.0 ug/ml
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin 1.0-5.0 ug/ml
  • Simple Western 10 ug/ml
  • Western Blot 0.5-2.0 ug/ml
Application Notes
This OXPAT antibody is useful for Western blot and Immunohistochemistry on paraffin-embedded sections. In WB a band can be seen at approx. 50 kDa, representing the OXPAT protein. Use in Immunohistochemistry-Frozen reported in scientific literature (PMID 24648545). Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID: 26096040).

In Simple Western only 10 - 15 uL of the recommended dilution is used per data point. Separated by Size-Wes, Sally Sue/Peggy Sue.
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control Peptide
OXPAT Peptide (NB110-60509PEP)
Read Publications using
NB110-60509 in the following applications:

Reactivity Notes

porcine reactivity reported in scientific literature (PMID: 29094660).Human, bovine and mouse. Immunogen displays the following percentage of sequence identity for non-tested species: sheep (94%), porcine (94%), rat (84%).

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS and 30% Glycerol
0.1% Sodium Azide
1.0 mg/ml
Immunogen affinity purified

Alternate Names for OXPAT Antibody - BSA Free

  • lipid storage droplet protein 5
  • LSDA5
  • LSDP5
  • MLDP
  • perilipin 5
  • perilipin-5


OXPAT (PLIN5/Perilipin 5) is a novel PAT-1 (Perilipin, ADRP and TIP47) that binds to lipid droplets (LDs) and protects them from lipolytic degradation. The tissue distribution of PAT-1 proteins differs considerably, however, all of them are involved in accumulation and metabolism of lipids in LDs. OXPAT covers LDs in the cytosol and its expression is highest in tissues with a high fat-oxidative capacity, such as heart, oxidative (type I) skeletal muscles and brown adipose tissue wherein the OXPAT contents parallel the LD content. OXPAT overexpression in OP-9 and COS-7 cells increased cellular triglyceride storage in parallel with increases in fatty acid oxidation and induction of gene expression of mitochondrial enzymes involved in oxidative metabolism. OXPAT has the potential of modulating the interaction of the major triacylglycerol lipase ATGL with LD as well as with its co-factor CGI-58 in a well control manner to regulate LD lipolysis. OXPAT expression is up-regulated by PPARalpha, and this regulation appears to be part of an expression program that shifts the metabolism of cells from fatty acid storage to oxidation.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Species: Hu, Mu, Po, Pm
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Applications: ICC/IF, IHC, IHC-Fr, IHC-P, WB
Species: Hu
Applications: ELISA, ICC/IF, WB
Species: Mu
Applications: IHC
Species: Hu, Mu, Rt
Applications: IHC, IHC-P, IP, WB
Species: Bv, Hu, Pm, Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-P, KO, WB
Species: Bv, Hu, Mu, Rb, Rt
Applications: ChIP, Flow, GS, ICC/IF, IHC, IHC-P, IP, KD, WB
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Applications: ELISA
Species: Ca, Ch, SyHa, Ha, Hu, Pm, Mu, Rt
Applications: IHC-Fr, KO, Simple Western, WB
Species: Hu, Mu, Rt
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Species: Bv, Hu, Mu
Applications: CyTOF-ready, ICC, IHC, ICFlow
Species: Hu
Applications: ELISA
Species: Hu, Mu, Po, Bv, Sh
Applications: WB, Simple Western, ICC/IF, IHC, IHC-Fr, IHC-P

Publications for OXPAT Antibody (NB110-60509)(14)

We have publications tested in 3 confirmed species: Human, Mouse, Porcine.

We have publications tested in 5 applications: Flow, ICC/IF, IHC-Fr, IP, WB.

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Showing Publications 1 - 10 of 14. Show All 14 Publications.
Publications using NB110-60509 Applications Species
Gan X, Zhao J, Chen Y et al. Plin5 inhibits proliferation and migration of vascular smooth muscle cell through interacting with PGC-1alpha following vascular injury Bioengineered Apr 1 2022 [PMID: 35470759] (WB, IP, Mouse) WB, IP Mouse
Fillmore N, Hou V, Sun J et al. Cardiac specific knock-down of peroxisome proliferator activated receptor alpha prevents fasting-induced cardiac lipid accumulation and reduces perilipin 2 PloS one Mar 8 2022 [PMID: 35259201] (WB, Mouse) WB Mouse
Zhong W, Fan B, Cong H et al. Oleic acid-induced perilipin 5 expression and lipid droplets formation are regulated by the PI3K/PPAR alpha pathway in HepG2 cells Appl Physiol Nutr Metab Aug 1 2019 [PMID: 31274012]
Larsen Steen, Vigelso Andreas, Dandanell Sune et al. Simvastatin-Induced Insulin Resistance May Be Linked to Decreased Lipid Uptake and Lipid Synthesis in Human Skeletal Muscle: the LIFESTAT Study. Journal of Diabetes Research 2018 Sep 12 [PMID: 30276217] (WB, Human) WB Human
Kristensen MD, Petersen SM, Moller KE et al. Obesity leads to impairments in the morphology and organization of human skeletal muscle lipid droplets and mitochondrial networks, which are resolved with gastric bypass surgery-induced improvements in insulin sensitivity Acta Physiol (Oxf) May 23 2018 [PMID: 29791782] (Human) Human
Lambertz J, Berger T, Mak TW et al. Lipocalin-2 in Fructose-Induced Fatty Liver Disease. Front Physiol 2017 Nov 28 [PMID: 29234288] (Mouse) Mouse
Zappaterra M, Mazzoni M, Zambonelli P, Davoli R. Investigation of the Perilipin 5 gene expression and association study of its sequence polymorphism with meat and carcass quality traits in different pig breeds animal. 2017 Nov 02 [PMID: 29094660] (Porcine) Porcine
Vigelso A, Gram M, Wiuff C et al. Effects of immobilization and aerobic training on proteins related to intramuscular substrate storage and metabolism in young and older men. Eur. J. Appl. Physiol. 2015 Dec 01 [PMID: 26626913] (WB, Human) WB Human
Revuelta-Lopez E, Cal R, Julve J et al. Hypoxia worsens the impact of intracellular triglyceride accumulation promoted by electronegative low-density lipoprotein in cardiomyocytes by impairing perilipin 5 upregulation. Int J Biochem Cell Biol 2015 Aug [PMID: 26096040]
Fahrenbach JP, Stoller D, Kim G et al. Abcc9 is required for the transition to oxidative metabolism in the newborn heart. FASEB J. 3/19/2014 [PMID: 24648545] (IHC-Fr, Mouse) IHC-Fr Mouse
Show All 14 Publications.

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Product General Protocols

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Secondary Antibodies


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Array NB110-60509

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Blogs on OXPAT.

OXPAT: Regulating Lipid Metabolism during Dietary Fluctuations
OXPAT is the mammalian form of the PAT (perilipin, adipophilin, and TIP47) gene family that consists of proteins associated with lipid droplets (LDs) in fat-storing adipocyte cells. They serve to protect LDs from natural lipases responsible for breaki...  Read full blog post.

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Gene Symbol PLIN5