ZAG Antibody [Biotin]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Biotin
• Concentration: LYOPH

ZAG Antibody [Biotin] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human ZAG
  Gln21-Ser298
  Accession # Q5XKQ4
• Specificity: Detects human ZAG in Western blots.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: AZGP1
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1 ug/mL
• Readout System:
  • Streptavidin Native Protein NBP2-29367
  • Streptavidin Native Protein NBP2-29370
  • Streptavidin Native Protein NBP2-29371

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ZAG Antibody [Biotin]

• alpha-2-glycoprotein 1, zinc
• alpha-2-glycoprotein 1, zinc-binding
• AZGP1
• ZA2G
• ZAG
• ZAGzn-alpha-2-GP
• zinc
• zinc-alpha-2-glycoprotein
• zn-alpha-2-glycoprotein
• ZNGP1

Background

ZAG (zinc-alpha ₂-glycoprotein; also ZA2G) is a 40 kDa, secreted member of the MHC class I family of proteins. It is produced by adipocytes and various epithelial cells that generate exocrine-type secretions. ZAG is reported to stimulate lipid breakdown and thus may play a role in lipid homeostasis. Mature human ZAG is 278 amino acids (aa) in length. It contains one MHC class I antigen region (aa 26‑201) and a C2‑type Ig‑like domain (aa 207‑292). Two alternate splice forms exist; one shows a 66 aa substitution for the C‑terminal 30 aa, and a second shows a nine Lys substitution for aa 151‑298. Mature human ZAG is 60% aa identical to mouse ZAG.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ZAG Antibody (BAF4764)(1)

Publication using BAF4764

• Shirin Moghaddam, Amirhossein Jalali, Amanda O’Neill, Lisa Murphy, Laura Gorman, Anne-Marie Reilly et al. Integrating Serum Biomarkers into Prediction Models for Biochemical Recurrence Following Radical Prostatectomy Cancers (Basel) 2021-08-19 [PMID: 34439316]

Bioinformatics

• Gene Symbol: AZGP1
• Uniprot:
  • Q5XKQ4()