Human Fetuin A Quantikine ELISA Kit

• Reactivity: Hu
• Applications: ELISA
• Conjugate: HRP

Human Fetuin A Quantikine ELISA Kit Summary

• Background: The Quantikine Human Fetuin A Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human Fetuin A in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant human Fetuin A and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human Fetuin A showed linear curves that were parallel to the standard curves obtained... using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human Fetuin A.
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• Specificity: Natural and recombinant human Fetuin A
• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: AHSG

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Fetuin A Quantikine ELISA Kit

• A2HS
• AHS
• AHSG
• alpha-2-HS-glycoprotein
• alpha-2-Z-globulin
• Ba-alpha-2-glycoprotein
• FETUAba-alpha-2-glycoprotein
• Fetuin A
• fetuin-A
• HSGA

Background

Fetuins are members of the cystatin family of proteases. Secreted by the liver, fetuins can be found at high levels in serum. Fetuin A promotes phagocytosis of apoptotic cells and plays a role in bone development, calcium homeostasis and insulin sensitivity. Fetuin B functions as an inhibitor of basic calcium phosphate precipitation.

⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for Fetuin A/AHSG (DFTA00)(20)

Publications using DFTA00

• Fröhling, T;Semo, D;Mirna, M;Paar, V;Shomanova, Z;Motloch, LJ;Rukosujew, A;Sindermann, JR;Lichtenauer, M;Pistulli, R; Novel Biomarkers as Potential Predictors of Decompensated Advanced Chronic Heart Failure-Single Center Study Journal of clinical medicine 2024-11-14 [PMID: 39598008] (Human)
• Ma?uj?o-Balcerska, E;Pietras, T; Adipocytokines levels as potential biomarkers for discriminating patients with a diagnosis of depressive disorder from healthy controls Journal of psychiatric research 2024-01-20 [PMID: 38290234] (Human)
• Giannouli, A;Stefanaki, C;Kouskoutis, C;Konidari, M;Mani, I;Konidari, K;Markantonis, SL;Mantzou, A;Dourakis, SP;Deligeoroglou, E;Bacopoulou, F; Hepatokine Profile in Adolescents with Polycystic Ovary Syndrome: A Case-Control Study Journal of clinical medicine 2023-09-04 [PMID: 37685811] (Human)
• K Wolk, D Wilsmann-T, K Witte, TC Brembach, C Kromer, S Gerdes, K Ghoreschi, K Reich, R Mössner, R Sabat Interleukin-19 Levels Are Increased in Palmoplantar Pustulosis and Reduced following Apremilast Treatment International Journal of Molecular Sciences, 2023-01-09;24(2):. 2023-01-09 [PMID: 36674793] (Human)
• Q Etienne, V Lebrun, M Komuta, B Navez, JP Thissen, IA Leclercq, N Lanthier Fetuin-A in Activated Liver Macrophages Is a Key Feature of Non-Alcoholic Steatohepatitis Metabolites, 2022-07-07;12(7):. 2022-07-07 [PMID: 35888749] (Human)
• MK Tiong, MMX Cai, ND Toussaint, SJ Tan, A Pasch, ER Smith Effect of nutritional calcium and phosphate loading on calciprotein particle kinetics in adults with normal and impaired kidney function Scientific Reports, 2022-05-05;12(1):7358. 2022-05-05 [PMID: 35513558] (Human)
• K Kim, TJ Oh, HC Cho, YK Lee, CH Ahn, BK Koo, JH Moon, SH Choi, HC Jang Liver fibrosis indices are related to diabetic peripheral neuropathy in individuals with type 2 diabetes Scientific Reports, 2021-12-21;11(1):24372. 2021-12-21 [PMID: 34934162] (Human)
• DS Harbuwono, BI Sazli, F Kurniawan, B Darmowidjo, S Koesnoe, DL Tahapary The impact of Ramadan fasting on Fetuin-A level in type 2 diabetes mellitus Heliyon, 2021-05-15;7(5):e06773. 2021-05-15 [PMID: 34041376] (Human)
• M Lassé, AP Pilbrow, T Kleffmann, E Andersson, A von Zychli, CMA Frampton, KK Poppe, RW Troughton, LK Lewis, TCR Prickett, CJ Pemberton, AM Richards, VA Cameron Fibrinogen and hemoglobin predict near future cardiovascular events in asymptomatic individuals Scientific Reports, 2021-02-25;11(1):4605. 2021-02-25 [PMID: 33633217] (Human)
• P Jirak, R Pistulli, M Lichtenaue, B Wernly, V Paar, LJ Motloch, R Rezar, C Jung, UC Hoppe, PC Schulze, D Kretzschma, RC Braun-Dull, T Bekfani Expression of the Novel Cardiac Biomarkers sST2, GDF-15, suPAR, and H-FABP in HFpEF Patients Compared to ICM, DCM, and Controls J Clin Med, 2020-04-15;9(4):. 2020-04-15 [PMID: 32326570] (Human)
• CT Chao, TH Yuan, HY Yeh, HY Chen, JW Huang, HW Chen Risk Factors Associated With Altered Circulating Micro RNA -125b and�Their Influences on Uremic Vascular Calcification Among Patients�With End-Stage Renal Disease J Am Heart Assoc, 2019-01-22;8(2):e010805. 2019-01-22 [PMID: 30646802] (Human)
• W Kandeel, W El-Shaer, A Sebaey, AA Abou-Taleb, A Fathy, B Elmohamady, AI Mansour Usefulness of serum fetuin-A level as a marker of erectile dysfunction Int. J. Impot. Res., 2017-04-20;0(0):. 2017-04-20 [PMID: 28424505] (Human)
• Nikolaos Tentolouri Association of plasma fetuin-a levels with peripheral arterial disease and lower extremity arterial calcification in subjects with type 2 diabetes mellitus J. Diabetes Complicat., 2016-11-12;0(0):. 2016-11-12 [PMID: 27899247] (Human)
• Proteomic Biomarkers Panel: New Insights in Chronic Kidney Disease Dis Markers, 2016-09-07;2016(0):3185232. 2016-09-07 [PMID: 27667892] (Human)
• Serum Interleukin-18, Fetuin-A, Soluble Intercellular Adhesion Molecule-1, and Endothelin-1 in Ankylosing Spondylitis, Psoriatic Arthritis, and SAPHO Syndrome Int J Mol Sci, 2016-08-03;17(8):. 2016-08-03 [PMID: 27527149] (Human)
• Hansen D, Rasmussen K, Rasmussen L, Bruunsgaard H, Brandi L The influence of vitamin D analogs on calcification modulators, N-terminal pro-B-type natriuretic peptide and inflammatory markers in hemodialysis patients: a randomized crossover study. BMC Nephrol, 2014-08-12;15(0):130. 2014-08-12 [PMID: 25112372] (Human)
• Serum fetuin-A levels are associated with the presence and severity of coronary artery disease in patients with type 2 diabetes. Biomarkers, 2013-03-01;18(2):160-4. 2013-03-01 [PMID: 23410047] (Human)
• Sun Q, Cornelis M, Manson J, Hu F Plasma levels of fetuin-A and hepatic enzymes and risk of type 2 diabetes in women in the U.S. Diabetes, 2012-08-24;62(1):49-55. 2012-08-24 [PMID: 22923470] (Human)
• Li M, Xu M, Bi Y Association between higher serum fetuin-A concentrations and abnormal albuminuria in middle-aged and elderly chinese with normal glucose tolerance. Diabetes Care, 2010-08-16;33(11):2462-4. 2010-08-16 [PMID: 20713686] (Human)
• Dasgupta S, Bhattacharya S, Biswas A NF-kappaB mediates lipid-induced fetuin-A expression in hepatocytes that impairs adipocyte function effecting insulin resistance. Biochem. J., 2010-08-01;429(3):451-62. 2010-08-01 [PMID: 20482516] (Human)

FAQs for Fetuin A/AHSG (DFTA00). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: AHSG