Von Willebrand Factor Antibody (S01-5D2)

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Western Blot: Von Willebrand Factor Antibody (S01-5D2) [NBP3-14887] - Western blot detection of Von Willebrand Factor in rat kidney, rat lung lysates using Von Willebrand Factor antibody. Predicted band size: 309kDa. ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
S01-5D2
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Von Willebrand Factor Antibody (S01-5D2) Summary

Description
Novus Biologicals Rabbit Von Willebrand Factor Antibody (S01-5D2) (NBP3-14887) is a recombinant monoclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthetic peptide of human Von Willebrand Factor (Uniprot#: P04275)
Source
HEK293
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
VWF
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1/1000-1/5000
Theoretical MW
309 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA
Preservative
0.01% Sodium Azide
Purity
Affinity purified

Alternate Names for Von Willebrand Factor Antibody (S01-5D2)

  • coagulation factor VIII VWF
  • F8
  • F8VWF
  • von Willebrand factor
  • VWD
  • vWF

Background

The glycoprotein encoded by this gene functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. It is crucial to the hemostasis process. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease. An unprocessed pseudogene has been found on chromosome 22.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Research Areas for Von Willebrand Factor Antibody (NBP3-14887)

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Blogs on Von Willebrand Factor.

Thrombomodulin - A multifunctional protein with roles in inflammation and coagulation
Thrombomodulin, also known as BDCA-3, is a glycosylated transmembrane protein present on the surface of vascular endothelial cells. Thrombomodulin is a high-affinity receptor for thrombin, a key protein in the coagulation cascade. Formation of the...  Read full blog post.

Von Willebrand Factor: An important mediator and carrier of hemostasis
Human Von Willebrand Factor (factor VIII R: Ag) is a 270 kDa multimeric plasma gylcoprotein. Important in the maintenance of hemostasis, it mediates platelet adhesion to injured vessel walls and serves as a carrier and stabilizer for coagulation facto...  Read full blog post.

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Bioinformatics

Gene Symbol VWF