Von Willebrand Factor Antibody (CL1957) - BSA Free

Western Blot: Von Willebrand Factor Antibody (CL1957) [NBP2-34494] - Lane 1: Marker [kDa]. Lane 2: Human spleen tissue lysate

Immunohistochemistry-Paraffin: Von Willebrand Factor Antibody (CL1957) [NBP2-34494] - Staining of human tonsil shows absence of immunoreactivity in lymphoid cells (negative control).

Immunohistochemistry-Paraffin: Von Willebrand Factor Antibody (CL1957) [NBP2-34494] - Staining of human rectum shows strong immunoreactivity in a blood vessel.

Immunohistochemistry-Paraffin: Von Willebrand Factor Antibody (CL1957) [NBP2-34494] - Staining of human fallopian tube shows strong positivity in blood vessels.

Immunohistochemistry-Paraffin: Von Willebrand Factor Antibody (CL1957) [NBP2-34494] - Staining of human cerebral cortex shows strong immunoreactivity in blood vessels.

Immunohistochemistry-Paraffin: Von Willebrand Factor Antibody (CL1957) [NBP2-34494] - Staining of human testis shows strong positivity in larger and smaller blood vessels.

• Reactivity: Hu
• Applications: WB, IHC
• Clone: CL1957
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free

Von Willebrand Factor Antibody (CL1957) - BSA Free Summary

• Description: Novus Biologicals Mouse Von Willebrand Factor Antibody (CL1957) - BSA Free (NBP2-34494) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed using a recombinant protein derived from P04275, with the exact immunogen sequence remaining proprietary.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: VWF
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
  • Western Blot 1 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Reactivity Notes

Expected identity based on immunogen sequence: Mouse (80%), Rat (80%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Protein A purified

Alternate Names for Von Willebrand Factor Antibody (CL1957) - BSA Free

• coagulation factor VIII VWF
• F8
• F8VWF
• von Willebrand factor
• VWD
• vWF

Background

The glycoprotein encoded by this gene functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. It is crucial to the hemostasis process. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease. An unprocessed pseudogene has been found on chromosome 22.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: VWF
• Uniprot:
  • P04275()