| Reactivity | Hu, MuSpecies Glossary |
| Applications | Flow, ICC/IF, IHC, IHC-P |
| Clone | TYRP1/1564R |
| Clonality | Monoclonal |
| Host | Rabbit |
| Conjugate | DyLight 755 |
| Additional Information | Recombinant Monoclonal Antibody. |
| Immunogen | Recombinant human full-length TYRP1 protein |
| Localization | Cytoplasmic |
| Marker | Melanoma Marker |
| Isotype | IgG Kappa |
| Clonality | Monoclonal |
| Host | Rabbit |
| Gene | TYRP1 |
| Purity | Protein A purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
|
| Application Notes | Optimal dilution of this antibody should be experimentally determined. |
| Storage | Store at 4C in the dark. |
| Buffer | 50mM Sodium Borate |
| Preservative | 0.05% Sodium Azide |
| Purity | Protein A purified |
![TYRP1 Antibody (TYRP1/1564R) [DyLight 755]](/sites/all/modules/enterprise-tech/et_datasheets/images/novus_guarantee.png "TYRP1 Antibody (TYRP1/1564R) [DyLight 755]")
Secondary Antibodies |
Isotype Controls |
| Alexa Fluor 350 | NBP2-54446AF350 | |
| Alexa Fluor 405 | NBP2-54446AF405 | |
| Alexa Fluor 488 | NBP2-54446AF488 | |
| Alexa Fluor 532 | NBP2-54446AF532 | |
| Alexa Fluor 594 | NBP2-54446AF594 | |
| Alexa Fluor 647 | NBP2-54446AF647 | |
| Alexa Fluor 700 | NBP2-54446AF700 | |
| Alexa Fluor 750 | NBP2-54446AF750 | |
| Allophycocyanin | NBP2-54446APC | |
| Biotin | NBP2-54446B | |
| DyLight 350 | NBP2-54446UV | |
| DyLight 405 | NBP2-54446V | |
| DyLight 488 | NBP2-54446G | |
| DyLight 550 | NBP2-54446R | |
| DyLight 594 | NBP2-54446DL594 | |
| DyLight 650 | NBP2-54446C | |
| DyLight 680 | NBP2-54446FR | |
| DyLight 755 | NBP2-54446IR | |
| FITC | NBP2-54446F | |
| HRP | NBP2-54446H | |
| Janelia Fluor 549 | NBP2-54446JF549 | |
| Janelia Fluor 646 | NBP2-54446JF646 | |
| PE | NBP2-54446PE | |
| PerCP | NBP2-54446PCP |
Diseases for TYRP1 Antibody (NBP2-54446IR)Discover more about diseases related to TYRP1 Antibody (NBP2-54446IR).
| Pathways for TYRP1 Antibody (NBP2-54446IR)View related products by pathway.
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PTMs for TYRP1 Antibody (NBP2-54446IR)Learn more about PTMs related to TYRP1 Antibody (NBP2-54446IR).
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Winter is coming, and TRPM8 welcomes the cold! TRPM8, or transient receptor potential melastatin 8, is a nonselective cation channel that is activated by cold environments and menthol-like cooling compounds. While TRPM8 is best known for its location in peripheral nerve endings, it has functio... Read full blog post. |
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.
| Gene Symbol | TYRP1 |
![Immunocytochemistry/Immunofluorescence: Tyrosinase Antibody (JA52-11) [NBP2-67232] - Staining Tyrosinase in B16F1 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.](http://images.novusbio.com/images2/Tyrosinase Antibody (JA52-11)-Immunocytochemistry-Immunofluorescence-NBP2-67232-img0005.jpg)
![Immunohistochemistry-Paraffin: Tyrosinase Antibody (JA52-11) [NBP2-67232] - Analysis of paraffin-embedded human stomach cancer tissue using anti-Tyrosinase antibody. Counter stained with hematoxylin.](http://images.novusbio.com/images2/Tyrosinase-Antibody-(JA52-11)-Immunohistochemistry-Paraffin-NBP2-67232-img0004.jpg)
![Immunocytochemistry/Immunofluorescence: Tyrosinase Antibody (JA52-11) [NBP2-67232] - Staining Tyrosinase in A431 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.](http://images.novusbio.com/images2/Tyrosinase-Antibody-(JA52-11)-Immunocytochemistry-Immunofluorescence-NBP2-67232-img0001.jpg)
![Western Blot: TRP2 Antibody [NBP1-86892] - Analysis in human cell line SK-MEL-30 and human cell line U-2 OS.](http://images.novusbio.com/images2/TRP2-Antibody-Western-Blot-NBP1-86892-img0013.jpg)
![Immunohistochemistry-Paraffin: TRP2 Antibody [NBP1-86892] - Staining of human skin.](http://images.novusbio.com/images2/TRP2-Antibody-Immunohistochemistry-Paraffin-NBP1-86892-img0015.jpg)
![Immunohistochemistry-Paraffin: TRP2 Antibody [NBP1-86892] - Staining of human skin shows strong cytoplasmic positivity in melanocytes.](http://images.novusbio.com/images2/TRP2-Antibody-Immunohistochemistry-Paraffin-NBP1-86892-img0003.jpg)
![Western Blot: Vanilloid R1/TRPV1 Antibody [NB100-1617] - Nociceptive behavior and CBS, TRPA1, TRPC6 and TRPV1 protein expression of the dorsal root ganglia obtained from normoglycemic and diabetic rats at 21 days post-streptozotocin injection. TRPV1 protein expression in normoglycemic and diabetic rats 21 days after streptozotocin injection. Data were normalized against Beta-actin and are expressed as the mean?+-?SEM of 5-6 animals. *Significantly different from control or normoglycemic (NG) group, #significantly different from vehicle (Veh, diabetic rats) group and &significantly different from SKF-96365 (SKF) group (P?<?0.05) determined by one-way ANOVA followed by the Student-Newman-Keuls' test Image collected and cropped by CiteAb from the following publication (https://bmcneurosci.biomedcentral.com/articles/10.1186/s12868-018-0483-3) licensed under a CC-BY licence.](http://images.novusbio.com/images2/Vanilloid R1-TRPV1 Antibody-Western Blot-NB100-1617-img0007.jpg)
![Immunocytochemistry/Immunofluorescence: Vanilloid R1/TRPV1 Antibody [NB100-1617] - CGRP and TRPV1 are co-expressed in most cultured trigeminal ganglion neurons. (A and C) CGRP expression in d2 trigeminal ganglion neurons plated on poly-d-lysine-coated coverslips. (B and D) The same culture shown in panel A or C costained for TRPV1 expression. Magnification bar = 200m (A and B) or 40m (C and D)](http://images.novusbio.com/images2/Vanilloid-R1-TRPV1-Antibody-Immunocytochemistry-Immunofluorescence-NB100-1617-img0006.jpg)
![Immunohistochemistry: Vanilloid R1/TRPV1 Antibody [NB100-1617] - TRPV1 Antibody [NB100-1617] - Dorsal Root Ganglion](http://images.novusbio.com/images2/Vanilloid-R1-TRPV1-Antibody-Immunohistochemistry-NB100-1617-img0001.jpg)
![Western Blot: TRPA1 Antibody [NB110-40763] - Expression and localization of TRPA1 channels in wild-type (WT) and APP/PS1 Tg mice. Brains were harvested from WT and APP/PS1 Tg mice at 8A months old. Western blot analysis of protein levels of TRPA1 and I+--tubulin. Image collected and cropped by Cite Ab from the following publication (Role of transient receptor potential ankyrin 1 channels in Alzheimer's disease. J Neuroinflammation (2016)) licensed under a CC-BY licence.](http://images.novusbio.com/images2/TRPA1-Antibody-Western-Blot-NB110-40763-img0012.jpg)
![Immunocytochemistry/Immunofluorescence: TRPA1 Antibody [NB110-40763] - Ai2 elicits TRPA1-dependent Ca2+ influx in astrocytes. Immunostaining of primary astrocytes from WT mice with anti-IgG and anti-TRPA1 antibody, then FITC-conjugated secondary antibody. Image collected and cropped by Cite Ab from the following publication (Role of transient receptor potential ankyrin 1 channels in Alzheimer's disease. J Neuroinflammation (2016)) licensed under a CC-BY licence.](http://images.novusbio.com/images2/TRPA1-Antibody-Immunocytochemistry-Immunofluorescence-NB110-40763-img0011.jpg)
![Immunohistochemistry: TRPA1 Antibody [NB110-40763] - Staining TRPA1 in mouse intestine.](http://images.novusbio.com/images2/TRPA1-Antibody-Immunohistochemistry-NB110-40763-img0008.jpg)
![Western Blot: MITF Antibody (21D1418) [NB100-56561] - Analysis of A375 lysate using MITF antibody at 4 ug/ml.](http://images.novusbio.com/images2/MITF-Antibody-(21D1418)-Western-Blot-NB100-56561-img0006.jpg)
![Immunocytochemistry/Immunofluorescence: MITF Antibody (21D1418) [NB100-56561] - HeLa cells were fixed in 4% paraformaldehyde for 10 min and permeabilized in 0.5% Triton X-100 in PBS for 5 minutes. The cells were incubated with anti-MITF Antibody (21D1418) NB100-56561 at 2 ug/ml overnight at 4C and detected with an anti-mouse Dylight 488 (Green) at a 1:500 dilution for 60 minutes. Cells were imaged using a 100X objective and digitally deconvolved.](http://images.novusbio.com/images2/MITF-Antibody-(21D1418)-Immunocytochemistry-Immunofluorescence-NB100-56561-img0008.jpg)
![Immunohistochemistry-Paraffin: MITF Antibody (21D1418) [NB100-56561] - Analysis of a FFPE tissue section of human skin using 1:200 dilution of MITF (21D1418) antibody. The staining was developed using HRP labeled anti-mouse secondary antibody and DAB reagent, and nuclei of cells were counter-stained with hematoxylin. General cytoplasmic staining appears enriched in melanocytes below the epidermis. Some nuclear reactivity is observed as well.](http://images.novusbio.com/images2/MITF-Antibody-(21D1418)-Immunohistochemistry-Paraffin-NB100-56561-img0007.jpg)
![Western Blot: PMEL17/SILV Antibody [NBP1-69571] - Sample Tissue: Human MCF7 Antibody Dilution: 1.0 ug/ml](http://images.novusbio.com/images2/PMEL17-SILV-Antibody-Western-Blot-NBP1-69571-img0006.jpg)
![Immunohistochemistry: PMEL17/SILV Antibody [NBP1-69571] - The inflammatory MITFlow/c-Junhigh cell state correlates with increased myeloid cell infiltration in human melanomas. Immunohistochemical analysis for gp100, CD45 and CD14 in representative cases from the Lund melanoma cohort. Small panels show zoom-in views, for example, to visualize morphology of CD45+/CD14+ tumour-infiltrating immune cells. Scale bars, 50 um. Image collected and cropped by CiteAb from the following publication (http://www.nature.com/articles/ncomms9755) licensed under a CC-BY licence.](http://images.novusbio.com/images2/PMEL17-SILV-Antibody-Immunohistochemistry-NBP1-69571-img0007.jpg)
![Western Blot: PMEL17/SILV Antibody [NBP1-69571] - This Anti-SILV antibody was used in Western Blot of HepG2 tissue lysate at a concentration of 1.25ug/ml.](http://images.novusbio.com/images2/PMEL17-SILV-Antibody-Western-Blot-NBP1-69571-img0003.jpg)
![Western Blot: Albumin Antibody [NB600-41532] - Analysis using the HRP conjugate of NB600-41532. Detection of Albumin in whole mouse liver extracts. Image courtesy of anonymous customer product review.](http://images.novusbio.com/images2/Albumin-Antibody-Western-Blot-NB600-41532-img0002.jpg)
![Immunocytochemistry/Immunofluorescence: Albumin Antibody [NB600-41532] - NLRP12 downregulates multiple JNK activating pathways in hepatocytes. For checking the purity of primary hepatocytes, hepatocytes isolated from healthy WT and Nlrp12-/- mouse livers were immunostained with antibody for hepatocyte-specific marker Albumin and counterstained with DAPI. Image collected and cropped by CiteAb from the following publication (https://elifesciences.org/articles/40396), licensed under a CC-BY licence.](http://images.novusbio.com/images2/Albumin-Antibody-Immunocytochemistry-Immunofluorescence-NB600-41532-img0003.jpg)
![Western Blot: POMC Antibody [NB100-1533] - Staining of NIH3T3 cell lysate with antibody at 0.3 ug/mL (A) and Rat Brain cell lysate with antibody at 2 ug/mL (B). 35 ug protein in RIPA buffer. Detected by chemiluminescence.](http://images.novusbio.com/images2/POMC-Antibody-Western-Blot-NB100-1533-img0005.jpg)
![Immunohistochemistry-Paraffin: POMC Antibody [NB100-1533] - Staining of paraffin embedded Human Pituitary Gland. Antibody at 2 ug/mL. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining.](http://images.novusbio.com/images2/POMC-Antibody-Immunohistochemistry-Paraffin-NB100-1533-img0003.jpg)
![Flow Cytometry: POMC Antibody [NB100-1533] - Flow cytometric analysis of paraformaldehyde fixed A431 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (1 ug/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.](http://images.novusbio.com/images2/POMC-Antibody-Flow-Cytometry-NB100-1533-img0006.jpg)
![Western Blot: TRPM8 Antibody [NBP1-97311] - Analysis of TRPM8 in PC12 cell lysate.](http://images.novusbio.com/images/TRPM8-Antibody-Western-Blot-NBP1-97311-img0003.jpg)
![Immunocytochemistry/Immunofluorescence: TRPM8 Antibody [NBP1-97311] - TRPM8 antibody was tested in U2OS cells with FITC (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and DyLight 550 (red).](http://images.novusbio.com/images2/TRPM8-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-97311-img0004.jpg)
![Immunohistochemistry: TRPM8 Antibody [NBP1-97311] - Analysis of TRPM8 in mouse prostate using DAB with hematoxylin counterstain.](http://images.novusbio.com/images2/TRPM8-Antibody-Immunohistochemistry-NBP1-97311-img0005.jpg)
![Western Blot: TRPV4 Antibody [NBP2-41262] - Analysis of TRPV4 in (A) human testis tissue and (B) SK-N-SH cell lysate with TRPV4 antibody at 1 ug/mL.](http://images.novusbio.com/images2/TRPV4-Antibody-Western-Blot-NBP2-41262-img0005.jpg)
![Immunocytochemistry/Immunofluorescence: TRPV4 Antibody [NBP2-41262] - Human kidney tissue with TRPV4 antibody at 5 ug/ml.](http://images.novusbio.com/images2/TRPV4-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-41262-img0007.jpg)
![Immunohistochemistry-Paraffin: TRPV4 Antibody [NBP2-41262] - Human kidney tissue with TRPV4 antibody at 2 ug/ml.](http://images.novusbio.com/images2/TRPV4-Antibody-Immunohistochemistry-Paraffin-NBP2-41262-img0006.jpg)
![Western Blot: TRPC3 Antibody [NBP1-77262] - Human brain tissue lysate. (A) 1 and (B) 2 ug/mL.](http://images.novusbio.com/images2/TRPC3-Antibody-Western-Blot-NBP1-77262-img0005.jpg)
![Immunohistochemistry-Paraffin: TRPC3 Antibody [NBP1-77262] - Mouse heart tissue with TRPC3 antibody at 2 ug/mL.](http://images.novusbio.com/images2/TRPC3-Antibody-Immunohistochemistry-Paraffin-NBP1-77262-img0004.jpg)
![Immunofluorescence: TRPC3 Antibody [NBP1-77262] - Mouse Heart cells with TRPC3 antibody at 20 ug/mL.](http://images.novusbio.com/images2/TRPC3-Antibody-Immunofluorescence-NBP1-77262-img0003.jpg)
![Western Blot: TRPC6 Antibody [NBP1-00142] - Analysis of TRPC6 in human placenta lysate (35ug protein in RIPA buffer) using this antibody at 0.03 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.](http://images.novusbio.com/images2/TRPC6-Antibody-Western-Blot-NBP1-00142-img0003.jpg)
![Western Blot: Catalase Antibody [NBP2-24916] - Analysis in liver lysate of 1) human 2) mouse and 3) rat at 0.1 ug/ml.](http://images.novusbio.com/images2/Catalase-Antibody-Western-Blot-NBP2-24916-img0001.jpg)
![Immunohistochemistry-Paraffin: Catalase Antibody [NBP2-24916] - Staining of human liver tissue using an isotype control (top) and this antibody (bottom) at 5 ug/ml.](http://images.novusbio.com/images2/Catalase-Antibody-Immunohistochemistry-Paraffin-NBP2-24916-img0002.jpg)
![Western Blot: Insulin Antibody (E2-E3 (same as INS04)) [NBP2-34260] - Probing of Western blots of pancreatic lysates from control and iron overloaded Tg40 PrP and PrP-/- mice with antibodies specific for insulin dimer and pentamer (upper and lower panels) shows decreased expression in Tg40 PrP relative to PrP-/- samples (lanes 1 & 5 vs. 3 & 7). Image collected and cropped by CiteAb from the following publication (nature.com/articles/s41598-018-24786-1), licensed under a CC-BY licence.](http://images.novusbio.com/images2/Insulin-Antibody-(E2-E3-(same-as-INS04))-Western-Blot-NBP2-34260-img0006.jpg)
![Immunohistochemistry: Insulin Antibody (E2-E3 (same as INS04)) [NBP2-34260] - Immunohistochemistry of pancreas shows relatively higher reactivity for insulin in PrP-/- relative to Tg40 PrP sections (panels 1 & 3). Iron overloading decreases insulin reactivity in Tg40 PrP but not in PrP-/- samples (panels 1 vs. 2 & 3 vs. 4). Reaction for glucagon is higher in iron overloaded Tg40 PrP relative to control samples (panels 5 & 6). The difference is minimal in PrP-/- samples (panels 7 & 8). Image collected and cropped by CiteAb from the following publication (http://www.nature.com/articles/s41598-018-24786-1), licensed under a CC-BY licence.](http://images.novusbio.com/images2/Insulin-Antibody-(E2-E3-(same-as-INS04))-Immunohistochemistry-NBP2-34260-img0005.jpg)
![Immunohistochemistry-Paraffin: Insulin Antibody (E2-E3 (same as INS04)) [NBP2-34260] - Formalin-fixed, paraffin-embedded human pancreas stained with insulin Monoclonal Antibody (E2-E3)](http://images.novusbio.com/images2/Insulin-Antibody-(E2-E3-(same-as-INS04))-Immunohistochemistry-Paraffin-NBP2-34260-img0002.jpg)
![Immunocytochemistry/Immunofluorescence: TRPC1 Antibody [NB100-98844] - IF (confocal) on rat trigeminal at 1 : 500 dilution using Rabbit antibody to 2d extracellular loop of TRPC1: whole serum, DAPI counterstained appearing in blue.](http://images.novusbio.com/images2/TRP1 Antibody-Immunocytochemistry-Immunofluorescence-NB100-98844-img0018.jpg)
![Immunocytochemistry/Immunofluorescence: TRPC1 Antibody [NB100-98844] - IF (confocal) on rat brain at 1:500 dilution using Rabbit antibody to 2d extracellular loop of TRPC1: whole serum, DAPI counterstained appearing in blue.](http://images.novusbio.com/images2/TRP1 Antibody-Immunocytochemistry-Immunofluorescence-NB100-98844-img0010.jpg)
![Immunocytochemistry/Immunofluorescence: TRPC1 Antibody [NB100-98844] - IF (confocal) on rat olfactory bulb at 1:500 dilution using Rabbit antibody to TRPC1: whole serum, DAPI counterstained appearing in blue.](http://images.novusbio.com/images2/TRP1 Antibody-Immunocytochemistry-Immunofluorescence-NB100-98844-img0014.jpg)
![Western Blot: TRPC4 Antibody [NBP1-20989] - Staining of Rat Brain lysate (35 ug protein in RIPA buffer) with antibody at 0.3 ug/mL. Primary incubation was 1 hour. Detected by chemiluminescence.](http://images.novusbio.com/images/TRPC4 Antibody-Western Blot-NBP1-20989-img0002.jpg)
![Immunohistochemistry-Paraffin: TRPC4 Antibody [NBP1-20989] - Staining of paraffin embedded Human Placenta with antibody at 4.75 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.](http://images.novusbio.com/images2/TRPC4-Antibody-Immunohistochemistry-Paraffin-NBP1-20989-img0004.jpg)
![Immunohistochemistry-Paraffin: TRPC4 Antibody [NBP1-20989] - Staining of paraffin embedded Human Kidney with antibody at 4.75 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.](http://images.novusbio.com/images2/TRPC4-Antibody-Immunohistochemistry-Paraffin-NBP1-20989-img0003.jpg)
![Western Blot: TRPM2 Antibody [NB110-81601] - Lane 1: CHO cells untransfected. Lane 2: CHO cell transfected with rat TRPM2 Lane 3: Mouse cortical neurons (cultured) Photo courtesy of Dr. Paco Herson, Oregon Health & Science University.](http://images.novusbio.com/images2/TRPM2 Antibody-Western Blot-NB110-81601-img0007.jpg)
![Immunocytochemistry/Immunofluorescence: TRPM2 Antibody [NB110-81601] - Neuro2a cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X PBS + 0.05% Triton X-100. The cells were incubated with anti-TRPM2 at 5 ug/mL overnight at 4C and detected with an anti-rabbit DyLight 488 (Green) at a 1:500 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.](http://images.novusbio.com/images2/TRPM2-Antibody-Immunocytochemistry-Immunofluorescence-NB110-81601-img0010.jpg)
![Immunocytochemistry/Immunofluorescence: TRPM2 Antibody [NB110-81601] - Staining of rat hippocampus using NB110-81601. TRPM2 is stained red, GFAP is stained green and nuclei staining is blue. Photo courtesy of Dr. Ji-Zhong Bai, The University of Auckland, New Zealand.](http://images.novusbio.com/images2/TRPM2 Antibody-Immunocytochemistry-Immunofluorescence-NB110-81601-img0006.jpg)
![Immunohistochemistry-Paraffin: Glutaminyl-peptide Cyclotransferase/QPCT Antibody [NBP1-81838] - Staining in human adrenal gland and liver tissues using anti-QPCT antibody. Corresponding QPCT RNA-seq data are presented for the same tissues.](http://images.novusbio.com/images2/Glutaminyl-peptide-Cyclotransferase-QPCT-Antibody-Immunohistochemistry-Paraffin-NBP1-81838-img0010.jpg)
![Western Blot: Glutaminyl-peptide Cyclotransferase/QPCT Antibody [NBP1-81838] - Analysis in control (vector only transfected HEK293T lysate) and QPCT over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).](http://images.novusbio.com/images2/Glutaminyl-peptide-Cyclotransferase-QPCT-Antibody-Western-Blot-NBP1-81838-img0011.jpg)
![Western Blot: Glutaminyl-peptide Cyclotransferase/QPCT Antibody [NBP1-81838] - Analysis in human cell line SK-MEL-30.](http://images.novusbio.com/images2/Glutaminyl-peptide-Cyclotransferase-QPCT-Antibody-Western-Blot-NBP1-81838-img0006.jpg)