Vanilloid R1/TRPV1 Antibody

Images

 
Western Blot: Vanilloid R1/TRPV1 Antibody [NBP1-97417] - Analysis of TRPV1 in following cell lysates: (1) Ntera2, (2) HepG2, (3) MCF7, and (4) Cos7.
Immunocytochemistry/ Immunofluorescence: Vanilloid R1/TRPV1 Antibody [NBP1-97417] - TRPV1 Antibody [NBP1-97417] - TRPV1 antibody was tested in Ntera-2 cells with FITC (green). Nuclei and alpha-tubulin were ...read more
Immunohistochemistry: Vanilloid R1/TRPV1 Antibody [NBP1-97417] - Putative receptor on the skin of Octopus vulgaris. Image from a verified customer review.

Product Details

Summary
Reactivity Hu, Mu, Rt, In, PmSpecies Glossary
Applications WB, ICC/IF, IHC, IHC (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Vanilloid R1/TRPV1 Antibody Summary

Immunogen
A synthetic peptide made to an N-terminal portion of the rat TRPV1 protein (between residues 1-50) [Uniprot: O35433]
Localization
Multi-pass membrane protein. Note: Mostly, but not exclusively expressed in post-synaptic dendritic spines.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TRPV1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000
  • Immunocytochemistry/Immunofluorescence 1:40
  • Immunohistochemistry
Application Notes
In Western Blot, a band is seen at ~100 kDa representing TRPV1. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. In ICC/IF, plasma membrane staining is observed in Ntera-2 cells. This antibody is not recommended for IHC-paraffin embedded sections. IHC reported in a customer review.
Control
Vanilloid R1/TRPV1 Knockout 293T Cell Lysate
Reviewed Applications
Read 1 Review rated 5
using
NBP1-97417 in the following applications:

Publications
Read Publications using
NBP1-97417 in the following applications:

  • 3 publications
  • WB
    2 publications

Reactivity Notes

Reactive to Octopus vulgaris.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Vanilloid R1/TRPV1 Antibody

  • Capsaicin Receptor
  • Osm-9-like TRP channel 1
  • OTRPC1
  • transient receptor potential cation channel subfamily V member 1
  • transient receptor potential cation channel, subfamily V, member 1
  • transient receptor potential vanilloid 1a
  • transient receptor potential vanilloid 1b
  • TRPV1
  • Vanilloid R1
  • Vanilloid receptor 1
  • vanilloid receptor subtype 1
  • VanilloidR1
  • VR1
  • VR1DKFZp434K0220

Background

TRPV1 (transient receptor potential cation channel subfamily V member 1, capsaicin receptor, vanilloid receptor, Vr1) is a polymodal nociceptor activated by heat, vanilloids (capsaicin), and protons. It is primarily expressed in the dorsal root ganglia and peripheral nerve endings. TRPV1 antagonists are a potential therapeutic target for many suffering chronic physical and neuropathic pain. However, due to its other role in the regulation of body temperature, these therapies are currently experiencing a barrier. On the other hand, TRPV1 agonists can be used to desensitize nerves after activation, thereby reducing pain. The research around TRPV1 is broad, where it is studied in fields such as anxiety, pain, oxidative stress, taste, inflammation, depression, respiratory disease, and various psychiatric disorders.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Vanilloid R1/TRPV1 Antibody (NBP1-97417)(6)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: ICC/IF, WB.


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ICC/IF
(3)
WB
(2)
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Human
(2)
Mouse
(3)
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Review for Vanilloid R1/TRPV1 Antibody (NBP1-97417) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Other.

Reviews using NBP1-97417:
Filter by Applications
IHC-P
(1)
All Applications
Filter by Species
Other
(1)
All Species
Images Ratings Applications Species Date Details
Immunohistochemistry-Paraffin Vanilloid R1/TRPV1 NBP1-97417
Enlarge
5
reviewed by:
Giulia Di Cristina
IHC-P Other 07/19/2016
View

Summary

ApplicationImmunohistochemistry-Paraffin
Sample Tested10 µm paraffin transversal sections of the arm of Octopus vulgaris
SpeciesOther
LotA-2

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Vanilloid R1/TRPV1 Antibody (NBP1-97417) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP1-97417AF350
Alexa Fluor 405 NBP1-97417AF405
Alexa Fluor 488 NBP1-97417AF488
Alexa Fluor 532 NBP1-97417AF532
Alexa Fluor 594 NBP1-97417AF594
Alexa Fluor 647 NBP1-97417AF647
Alexa Fluor 700 NBP1-97417AF700
Alexa Fluor 750 NBP1-97417AF750
Biotin NBP1-97417B
DyLight 350 NBP1-97417UV
DyLight 405 NBP1-97417V
DyLight 488 NBP1-97417G
DyLight 550 NBP1-97417R
DyLight 650 NBP1-97417C
DyLight 680 NBP1-97417FR
DyLight 755 NBP1-97417IR
FITC NBP1-97417F
HRP NBP1-97417H
Janelia Fluor 549 NBP1-97417JF549
Janelia Fluor 646 NBP1-97417JF646

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Bioinformatics Tool for Vanilloid R1/TRPV1 Antibody (NBP1-97417)

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Recent Reviews

5
5
1
4
0
3
0
2
0
1
0

Giulia Di Cristina
07/19/2016
Application: IHC-P
Species: Other

Bioinformatics

Gene Symbol TRPV1
Entrez
Uniprot