Western Blot: Vanilloid R1/TRPV1 Antibody [NBP1-97417] - Analysis of TRPV1 in following cell lysates: (1) Ntera2, (2) HepG2, (3) MCF7, and (4) Cos7.
Immunocytochemistry/ Immunofluorescence: Vanilloid R1/TRPV1 Antibody [NBP1-97417] - TRPV1 Antibody [NBP1-97417] - TRPV1 antibody was tested in Ntera-2 cells with FITC (green). Nuclei and alpha-tubulin were ...read more
Immunohistochemistry: Vanilloid R1/TRPV1 Antibody [NBP1-97417] - Putative receptor on the skin of Octopus vulgaris. Image from a verified customer review.
In Western Blot, a band is seen at ~100 kDa representing TRPV1. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. In ICC/IF, plasma membrane staining is observed in Ntera-2 cells. This antibody is not recommended for IHC-paraffin embedded sections. IHC reported in a customer review.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.02% Sodium Azide
Immunogen affinity purified
Alternate Names for Vanilloid R1/TRPV1 Antibody
Osm-9-like TRP channel 1
transient receptor potential cation channel subfamily V member 1
transient receptor potential cation channel, subfamily V, member 1
transient receptor potential vanilloid 1a
transient receptor potential vanilloid 1b
Vanilloid receptor 1
vanilloid receptor subtype 1
TRPV1 (transient receptor potential cation channel subfamily V member 1, capsaicin receptor, vanilloid receptor, Vr1) is a polymodal nociceptor activated by heat, vanilloids (capsaicin), and protons. It is primarily expressed in the dorsal root ganglia and peripheral nerve endings. TRPV1 antagonists are a potential therapeutic target for many suffering chronic physical and neuropathic pain. However, due to its other role in the regulation of body temperature, these therapies are currently experiencing a barrier. On the other hand, TRPV1 agonists can be used to desensitize nerves after activation, thereby reducing pain. The research around TRPV1 is broad, where it is studied in fields such as anxiety, pain, oxidative stress, taste, inflammation, depression, respiratory disease, and various psychiatric disorders.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Zhu T, Niu J, Su C et al. Botulinum Neurotoxin A Prevents the Development of Nitroglycerin-Induced Chronic Migraine via Inhibition of CGRP and NLRP3 Inflammasomes in Mice Research Square Jun 18 2020 (WB, Mouse)
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