TRPC3 Antibody

Images

 
Western Blot: TRPC3 Antibody [NBP1-77262] - Human brain tissue lysate. (A) 1 and (B) 2 ug/mL.
Immunocytochemistry/ Immunofluorescence: TRPC3 Antibody [NBP1-77262] - Mouse Heart cells.
Immunohistochemistry-Paraffin: TRPC3 Antibody [NBP1-77262] - Mouse heart tissue.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

TRPC3 Antibody Summary

Immunogen
Antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human TRPC3. The immunogen is located within amino acids 760 - 810 of TRPC3.
Predicted Species
Rat (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TRPC3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.5-1 ug/ml
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 20 ug/mL
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 2 ug/ml
Theoretical MW
96 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control Peptide
TRPC3 Peptide (NBP1-77262PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TRPC3 Antibody

  • hTrp3
  • hTrp-3
  • short transient receptor potential channel 3
  • transient receptor potential cation channel, subfamily C, member 3
  • transient receptor potential channel 3
  • Transient receptor protein 3
  • TRP3
  • TRP-3
  • TrpC3

Background

The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the canonical TRP (TRPC) family. The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types. Furthermore, the members of the TRPC3/6/7 subfamily can be activated by diacylglycerol analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors. TRPC3 encodes a Ca2+-permeant channel that is agonist-activated but not store-operated or directly receptor-activated. TRPC3 physically interacts with TRPC6 and TRPC7 and forms functional tetrameric channels.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for TRPC3 Antibody (NBP1-77262). (Showing 1 - 2 of 2 FAQ).

  1. I would like to test some of your TRPC3 antibodies in my model system (Xenopus), but they have not been proven to work in this species. Do you offer any guarantee, or beta testing program. We would be happy to send you any images we produce if the antibody works (WB, IHC, ICC). We know that TRPC1-5 are expressed in our system (Xenopus spinal cord).
    • We do offer a testing program, the Innovators Reward Program. Our Innovator’s Reward program is designed to support your innovative research with minimal financial risk to you. Should you decide to use one of our products in an application or species for which it has not been tested all you need to do is submit a full review of the antibody with an image to qualify.
  2. I recently bought your company a antibodies.In the instruction book,Concentration sayPlease see the vial label for concentration, but in the vial label is nothing. So i am so puzzled. Why has this kind of situation ?
    • The concentration of this product is 1.0mg/ml. I apologize that this is not on the vial.

Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for TRPC3 Antibody (NBP1-77262)

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Bioinformatics

Gene Symbol TRPC3
Entrez
Uniprot