Biological Strategies: Knockdown Validated: TRPM8 Antibody [NBP1-97311] - The results of co-immunoprecipitation (CoIP) confirmed interaction between NFkB and TRPM8. CoIPs were also performed with TRPM8 ...read more
Biological Strategies: Immunocytochemistry/ Immunofluorescence: TRPM8 Antibody [NBP1-97311] - Co-localization of TRPM8 and TNFa in the cytoplasm (cold condition and 500 nM menthol). Data are shown as the mean +/- ...read more
Biological Strategies: Western Blot: TRPM8 Antibody [NBP1-97311] - Brain cooling means putting the anesthetized mouse brain on the artificial ice. Normal means the room temperature (25C). Data are shown as the ...read more
Immunohistochemistry: TRPM8 Antibody [NBP1-97311] - Analysis of TRPM8 in mouse prostate using DAB with hematoxylin counterstain.
Western Blot: TRPM8 Antibody [NBP1-97311] - Analysis of TRPM8 in PC12 cell lysate.
Immunocytochemistry/ Immunofluorescence: TRPM8 Antibody [NBP1-97311] - TRPM8 antibody was tested in U2OS cells with FITC (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and DyLight 550 (red).
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.4)
0.05% Sodium Azide
Immunogen affinity purified
Alternate Names for TRPM8 Antibody - BSA Free
Long transient receptor potential channel 6
short form of the TRPM8 cationic channel
transient receptor potential cation channel, subfamily M, member 8
Transient receptor potential p8
transient receptor potential subfamily M member 8
TRPP8transient receptor potential cation channel subfamily M member 8
TRPM8 (TRPP8, LTRPC6) is a transient receptor cation channel that has been shown to be a major cold receptor in sensory neurons. TRPM8 has been theorized to be activated by cold temperatures, voltage, calcium store depletion, some lipids, and also the compounds that produce cooling sensations such as menthol or icilin. TRPM8 is aberrantly over-expressed in pancreatic cancer along with colon, lung, breast and skin cancers, and is proposed to be required for cellular proliferation.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
TRPM8: The Multi-functional Ion Channel TRPM8 is a transmembrane homo-tetramer ion channel that is activated by cold temperatures, cooling agents, and menthol stimuli. It belongs to a subgroup within the larger family of TRP cation channels (including the TRPV1 capsaicin receptor) that are ... Read full blog post.
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