TSG-6 Antibody (259820)

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB
Clone
259820
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Formulation Size Price

TSG-6 Antibody (259820) Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human TSG-6
Trp18-Leu277
Accession # P98066
Specificity
Detects human and mouse TSG-6 in direct ELISAs and Western blots.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
TNFAIP6
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 ug/mL
Reviewed Applications
Read 2 Reviews rated 4
using
MAB2104 in the following application:

Publications
Read Publications using
MAB2104 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A or G purified from hybridoma culture supernatant
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TSG-6 Antibody (259820)

  • Hyaluronate-binding protein
  • TNF alpha-induced protein 6
  • TNFAIP6
  • TNF-stimulated gene 6 protein
  • TSG6
  • TSG-6
  • TSG-6tumor necrosis factor alpha-inducible protein 6
  • TSG6tumor necrosis factor-inducible gene 6 protein
  • Tumor necrosis factor alpha-induced protein 6
  • tumor necrosis factor, alpha-induced protein 6
  • tumor necrosis factor-stimulated gene-6 protein

Background

TSG-6 is a secreted hyaluronan-binding protein composed of a link domain and Cub domain. It is induced in many cell types by inflammatory mediators. Via its link domain, TSG-6 is a potent inhibitor of polymorphonuclear leukocyte migration. TSG-6 forms a stable complex with the serine protease inhibitor Inter-alpha -Inhibitor (I alpha I) and potentiates the anti-plasmin activity of I alpha I.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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MAB2104
Species: Hu, Mu
Applications: WB

Publications for TSG-6 Antibody (MAB2104)(5)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: Neutralization, Western Blot.


Filter By Application
Neutralization
(1)
Western Blot
(4)
All Applications
Filter By Species
Human
(3)
Mouse
(2)
All Species
Showing Publications 1 - 5 of 5.
Publications using MAB2104 Applications Species
DJ Kota, KS Prabhakara, N Toledano-F, D Bhattarai, Q Chen, B DiCarlo, P Smith, F Triolo, PL Wenzel, CS Cox, SD Olson Prostaglandin E2 Indicates Therapeutic Efficacy Of Mesenchymal Stem Cells In Experimental Traumatic Brain Injury Stem Cells, 2017;0(0):. 2017 [PMID: 28233425] (Western Blot, Human) Western Blot Human
TNF?-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury Proc. Natl. Acad. Sci. U.S.A., 2016;113(50):E8151-E8158. 2016 [PMID: 27911817] (Western Blot, Mouse) Western Blot Mouse
Fujita R, Tamai K, Aikawa E, Nimura K, Ishino S, Kikuchi Y, Kaneda Y Endogenous mesenchymal stromal cells in bone marrow are required to preserve muscle function in mdx mice. Stem Cells, 2015;33(3):962-75. 2015 [PMID: 25408548] (Neutralization, Mouse) Neutralization Mouse
Zhang S, He H, Day AJ, Tseng SC Constitutive expression of inter-alpha-inhibitor (IalphaI) family proteins and tumor necrosis factor-stimulated gene-6 (TSG-6) by human amniotic membrane epithelial and stromal cells supporting formation of the heavy chain-hyaluronan (HC-HA) complex. J. Biol. Chem., 2012;287(15):12433-44. 2012 [PMID: 22351758] (Western Blot, Human) Western Blot Human
He H, Li W, Tseng DY, Zhang S, Chen SY, Day AJ, Tseng SC Biochemical characterization and function of complexes formed by hyaluronan and the heavy chains of inter-alpha-inhibitor (HC*HA) purified from extracts of human amniotic membrane. J. Biol. Chem., 2009;284(30):20136-46. 2009 [PMID: 19491101] (Western Blot, Human) Western Blot Human

Reviews for TSG-6 Antibody (MAB2104) (2) 42

Average Rating: 4
(Based on 2 reviews)
We have 2 reviews tested in 1 species: Human.

Reviews using MAB2104:
Filter by Applications
WB
(1)
IHC-Fr
(1)
All Applications
Filter by Species
Human
(2)
All Species
Images Ratings Applications Species Date Details
 
reviewed by:
Anonymous
WB Human 02/19/2015
View

Summary

ApplicationWestern Blot
Sample TestedSee PMID 22351758
SpeciesHuman

Blocking

Blocking DetailsSee PMID 22351758

Details

Detection NotesSee PMID 22351758

Comments

CommentsIndependent review from antibodyresource.comPublished in PMID 22351758
 
reviewed by:
Anonymous
IHC-Fr Human 02/19/2015
View

Summary

ApplicationImmunohistochemistry-Frozen
Sample TestedSee PMID 22351758
SpeciesHuman
Special ApplicationsIndependent review from antibodyresource.com (Published in PMID 22351758)

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FAQs for TSG-6 Antibody (MAB2104) (0)

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Secondary Antibodies

 

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Recent Reviews

4
5
0
4
2
3
0
2
0
1
0

 
Anonymous
02/19/2015
Application: WB
Species: Human

 
Anonymous
02/19/2015
Application: IHC-Fr
Species: Human

Bioinformatics

Gene Symbol TNFAIP6
Uniprot