Reactivity | MuSpecies Glossary |
Applications | WB, IP, B/N |
Clonality | Polyclonal |
Host | Goat |
Conjugate | Unconjugated |
Concentration | LYOPH |
Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse Serpin D1/Heparin Cofactor II Glu24-Ser478 Accession # P49182 |
Specificity | Detects mouse Serpin D1/Heparin Cofactor II in direct ELISAs and Western blots. |
Source | N/A |
Isotype | IgG |
Clonality | Polyclonal |
Host | Goat |
Gene | SERPIND1 |
Purity Statement | Antigen Affinity-purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
Preservative | No Preservative |
Concentration | LYOPH |
Reconstitution Instructions | Reconstitute at 0.2 mg/mL in sterile PBS. |
Serpin D1 is a member of the Serpin superfamily of the serine protease inhibitors (1). Similar to Serpins A5 and C1, it inhibits thrombin and this activity is enhanced by heparin. Interestingly, a C-terminal His-tagged recombinant Serpin D1 had enhanced heparin effect, which was maintained in a plasma-based thrombin inhibition assay (2). Congenital Serpin D1 deficiency is a potential risk factor for thrombosis (3). Mouse Serpin D1 is synthesized as a 478 amino acid precursor with a 23 amino acid signal peptide (4). The mature chain (residues 24 to 478) is secreted.
Secondary Antibodies |
Isotype Controls |
Diseases for Serpin D1/Heparin Cofactor II Antibody (AF1265)Discover more about diseases related to Serpin D1/Heparin Cofactor II Antibody (AF1265).
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PTMs for Serpin D1/Heparin Cofactor II Antibody (AF1265)Learn more about PTMs related to Serpin D1/Heparin Cofactor II Antibody (AF1265).
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