Human Pentraxin 3/TSG-14 DuoSet ELISA, 15 Plate



Product Details

Reactivity HuSpecies Glossary
Applications ELISA

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Human Pentraxin 3/TSG-14 DuoSet ELISA, 15 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
See PDF Datasheet for details
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details


Application Notes
No significant interference observed with available related molecules.
Read Publications using DY1826.

Packaging, Storage & Formulations

Store the unopened product at 2 - 8 °C. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Pentraxin 3/TSG-14 DuoSet ELISA, 15 Plate

  • alpha-induced protein 5
  • pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor
  • Pentaxin-related protein PTX3
  • Pentraxin 3
  • pentraxin 3, long
  • pentraxin-3
  • pentraxin-related gene, rapidly induced by IL-1 beta
  • pentraxin-related protein PTX3
  • PTX3
  • TNF alpha-induced protein 5
  • TSG14
  • TSG-14
  • TSG-14pentaxin-related gene, rapidly induced by IL-1 beta
  • Tumor necrosis factor alpha-induced protein 5
  • tumor necrosis factor, alpha-induced protein 5
  • Tumor necrosis factor-inducible gene 14 protein
  • tumor necrosis factor-inducible protein TSG-14


Pentraxin 3 (PTX3), also known as TNF-stimulated gene 14 (TSG-14), is a secreted glycoprotein belonging to the Pentraxin family of proteins. It is the prototypical long Pentraxin, exhibiting a C-terminal Pentraxin domain characteristic of the family, and a unique N-terminal domain. It is produced by several cell types including endothelial and mononuclear cells. PTX3 acts as a pattern recognition receptor with non-redundant roles in the innate immune response to several microbial agents including the fungal pathogen Aspergillus fumigatus. Overexpression leads to enhanced pro-inflammatory responses. PTX3 is induced in response to LPS and inflammatory cytokines including TNF-alpha and IL-1 beta.

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Publications for Pentraxin 3/TSG-14 (DY1826)(12)

We have publications tested in 2 confirmed species: Human, Mouse.

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Showing Publications 1 - 10 of 12. Show All 12 Publications.
Publications using DY1826 Applications Species
KN Lee, KH Park, YM Kim, I Cho, TE Kim Prediction of emergency cerclage outcomes in women with cervical insufficiency: The role of inflammatory, angiogenic, and extracellular matrix-related proteins in amniotic fluid PLoS ONE, 2022;17(5):e0268291. 2022 [PMID: 35536791] (Human) Human
N Hwang, MY Kwon, JM Woo, SW Chung Oxidative Stress-Induced Pentraxin 3 Expression Human Retinal Pigment Epithelial Cells is Involved in the Pathogenesis of Age-Related Macular Degeneration Int J Mol Sci, 2019;20(23):. 2019 [PMID: 31795454] (Human) Human
ME O'Brien, D Chandra, RC Wilson, CM Karoleski, CR Fuhrman, JK Leader, J Pu, Y Zhang, A Morris, S Nouraie, J Bon, Z Urban, FC Sciurba Loss of skin elasticity is associated with pulmonary emphysema, biomarkers of inflammation, and matrix metalloproteinase activity in smokers Respir. Res., 2019;20(1):128. 2019 [PMID: 31234847] (Human) Human
K Bendí?ková, F Tidu, M De Zuani, MH Kohoutková, I Andrej?ino, A Pompeiano, S B?lášková, G Forte, T Zelante, J Fri? Calcineurin inhibitors reduce NFAT-dependent expression of antifungal pentraxin-3 by human monocytes J. Leukoc. Biol., 2019;0(0):. 2019 [PMID: 30934147] (Human) Human
NV Batista, M Barbagallo, VLS Oliveira, T Castro-Gom, RDR Oliveira, P Louzada-Ju, GRC Pinheiro, A Mantovani, MM Teixeira, C Garlanda, FA Amaral The Long Pentraxin 3 Contributes to Joint Inflammation in Gout by Facilitating the Phagocytosis of Monosodium Urate Crystals J. Immunol., 2019;0(0):. 2019 [PMID: 30718300] (Human) Human
V Ciancarell, L Lembo-Fazi, I Paciello, AK Bruno, S Jaillon, S Berardi, M Barbagallo, S Meron-Suda, D Cohen, A Molinaro, G Rossi, C Garlanda, ML Bernardini Role of a fluid-phase PRR in fighting an intracellular pathogen: PTX3 in Shigella infection PLoS Pathog., 2018;14(12):e1007469. 2018 [PMID: 30532257] (Human) Human
T Akhter, AK Wikström, M Larsson, A Larsson, G Wikström, T Naessen Serum Pentraxin 3 is associated with signs of arterial alteration in women with preeclampsia Int. J. Cardiol., 2017;0(0):. 2017 [PMID: 28377191] (Human) Human
Narae Hwang Tunicamycin-induced Endoplasmic Reticulum Stress Upregulates the Expression of Pentraxin 3 in Human Retinal Pigment Epithelial Cells Korean J Ophthalmol, 2016;30(6):468-478. 2016 [PMID: 27980366] (Human) Human
Foo , Suan-Sin, Chen , Weiqiang, Taylor , Adam, Sheng , Kuo-Chin, Yu , Xing, Teng , Terk-Shi, Reading , Patrick, Blanchard , Helen, Garlanda , Cecilia, Mantovani , Alberto, Ng , Lisa F P, Herrero , Lara J, Mahalingam , Suresh Role of pentraxin 3 in shaping arthritogenic alphaviral disease: from enhanced viral replication to immunomodulation. PLoS Pathog, 2015;11(2):e1004649. 2015 [PMID: 25695775] (Human) Human
Ketter P, Guentzel M, Schaffer B, Herzig M, Wu X, Montgomery R, Parida B, Fedyk C, Yu J, Jorgensen J, Chambers J, Cap A, Arulanandam B Severe Acinetobacter baumannii sepsis is associated with elevation of pentraxin 3. Infect Immun, 2014;82(9):3910-8. 2014 [PMID: 25001601] (Mouse) Mouse
Show All 12 Publications.

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Gene Symbol PTX3