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Alternate Names for Human Pentraxin 3/TSG-14 DuoSet ELISA, 15 Plate
alpha-induced protein 5
pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor
Pentaxin-related protein PTX3
pentraxin 3, long
pentraxin-related gene, rapidly induced by IL-1 beta
pentraxin-related protein PTX3
TNF alpha-induced protein 5
TSG-14pentaxin-related gene, rapidly induced by IL-1 beta
Tumor necrosis factor alpha-induced protein 5
tumor necrosis factor, alpha-induced protein 5
Tumor necrosis factor-inducible gene 14 protein
tumor necrosis factor-inducible protein TSG-14
Pentraxin 3 (PTX3), also known as TNF-stimulated gene 14 (TSG-14), is a secreted glycoprotein belonging to the Pentraxin family of proteins. It is the prototypical long Pentraxin, exhibiting a C-terminal Pentraxin domain characteristic of the family, and a unique N-terminal domain. It is produced by several cell types including endothelial and mononuclear cells. PTX3 acts as a pattern recognition receptor with non-redundant roles in the innate immune response to several microbial agents including the fungal pathogen Aspergillus fumigatus. Overexpression leads to enhanced pro-inflammatory responses. PTX3 is induced in response to LPS and inflammatory cytokines including TNF-alpha and IL-1 beta.
PRODUCT AVAILABILITY: Update Regarding the Evolving COVID-19 Situation
Bio-Techne appreciates the critical role that you and our products and services play in research efforts to further scientific innovation and discovery. We are continually assessing our manufacturing and supplier capabilities during the COVID-19 situation and are implementing precautionary measures to ensure uninterrupted supply of products and services. Currently, and as we abide by local shelter in place orders across the world, we are fully operational and do not anticipate any material supply disruptions across our Bio-Techne brands and product lines. As the situation evolves, our goal is to utilize preventive measures to reduce the threat that COVID-19 poses to our ability to meet the needs of our customers globally.