TLR6 Antibody [DyLight 405]


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Product Details

Reactivity Hu, Mu, Rt, PmSpecies Glossary
Applications WB
Please see the vial label for concentration. If unlisted please contact technical services.

Order Details

Available Conjugates
Catalog# & Conjugate Size Price

TLR6 Antibody [DyLight 405] Summary

Synthetic peptide made to a C-terminal portion of the human TLR6 protein (within residues 700-796). [Swiss-Prot# Q9Y2C9]
Cell membrane; Single-pass type I membrane protein
Predicted Species
Sheep (92%)
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C in the dark.
DyLight 405
DyLight 405 (A=400, E=420)
50mM Sodium Borate
0.05% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.
Immunogen affinity purified


Application Notes
This TLR6 antibody is useful for Western blot, where a band is seen at ~96 kDa.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
96 kDa

Reactivity Notes

Human, mouse, primate and rat. Immunogen sequence has 92% homology to sheep.

Alternate Names for TLR6 Antibody [DyLight 405]

  • CD286 antigen
  • CD286
  • toll-like receptor 6


TLR6 (toll-like receptor 6, also called CD286) belongs the family of TLRs which are membrane receptors with potential of acting as gatekeepers of the innate immunity through recognizing microbial components and initiating activation of an adequate immune response. Localized in cell membrane as well as in cytoplasmic vesicle/phagosome membrane as single-pass type I membrane protein, TLR6 is expressed in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells. TLR6 participates in the innate immune response to Gram-+ve bacteria and fungi. It specifically recognize diacylated/triacylated lipopeptides, and has the ability to recognize mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor, phenol-soluble modulin and Borrelia burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. It acts via MYD88 and TRAF6, leading to NFkB activation, cytokine secretion and inflammatory response. Moreover, it has been shown to bind MYD88 and dimerize with TLR2, wherein TLR6- TLR2 heterodimers recognize a large number of lipidcontaining molecules and transducers inflammatory signalling in a variety of cell type.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies


Isotype Controls

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Blogs on TLR6.

Exploring Various Studies on TLR6 Expression
The protein TLR6 is one member of the large Toll-like receptor (TLR) family, which governs the activation of the innate immunity system and pathogen recognition in cells. The TLR family is highly conserved from Drosophila to humans, and all the family...  Read full blog post.

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Gene Symbol TLR6

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