TLR10 Antibody (25F9) [Alexa Fluor® 488]

Immunocytochemistry/Immunofluorescence: TLR10 Antibody (25F9) [Alexa Fluor (R) 488] [DDX0490A488] - Immunofluorescent staining of hTLR10- transfected COP5 cells with 25F9.

Flow Cytometry: TLR10 Antibody (25F9) [Alexa Fluor (R) 488] [DDX0490A488] - Staining of TLR10-transfected COP5 cells with 25F9.

• Reactivity: Hu
• Applications: Flow, ICC/IF, IHC
• Clone: 25F9
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

TLR10 Antibody (25F9) [Alexa Fluor® 488] Summary

• Immunogen: TLR10/CD290 was used as immunogen.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: TLR10
• Purity: Ion exchange chromatography

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:10-1:1000
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry 1:10 - 1:500
• Application Notes: Flow Cytometry

Reactivity Notes

Human

Packaging, Storage & Formulations

• Storage: Store at -20C in the dark. Avoid freeze-thaw cycles.
• Buffer: Antibody in PBS and 50% Glycerol
• Preservative: No Preservative
• Purity: Ion exchange chromatography

Notes

This product is manufactured by Eurobio Scientific (formerly Dendritics) and distributed by Novus Biologicals.

Alternate Names for TLR10 Antibody (25F9) [Alexa Fluor® 488]

• CD290 antigen
• CD290
• MGC104967
• MGC126398
• MGC126399
• TLR10
• toll-like receptor 10

Background

Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR10 is highly homologous to TLRs 1 and 6 and is most highly expressed in lymphoid tissues. Most recently genetic variation in TLR10 has been associated with contributing to asthma risk. It should be noted that TLR10 exists in mice only as a pseudogene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TLR10