Mouse IL-13 DuoSet ELISA, 15 Plate

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

Mouse IL-13 DuoSet ELISA, 15 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Il13

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using
DY413 in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse IL-13 DuoSet ELISA, 15 Plate

  • ALRHMGC116789
  • BHR1interleukin-13
  • IL13
  • IL-13
  • IL-13MGC116788
  • interleukin 13
  • MGC116786
  • NC30
  • P600

Background

IL-13 (Interleukin-13) plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. IL-13 suppresses the production of proinflammatory cytokines and other cytotoxic substances by macrophages, fibroblasts, and endothelial cells. It promotes B cell activation, immunoglobulin class switching to IgE, and the upregulation of CD23/Fc epsilon RII. IL-13 signals through a receptor complex containing IL-13 R alpha 1 and IL-4 R alpha. This complex also functions as the type 2 IL-4 receptor. IL-13 R alpha 2 binds IL-13 and prevents IL-13 from signaling through the IL-13 R alpha 1/IL-4 R alpha complex. IL-13-bound IL-13 R alpha 2 can directly promote tumor cell invasiveness and the development of tissue fibrosis.

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Publications for IL-13 (DY413)(134)

We have publications tested in 4 confirmed species: Human, Mouse, Rat, Transgenic Mouse.

We have publications tested in 1 application: ELISA Capture.


Filter By Application
ELISA Capture
(1)
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Filter By Species
Human
(1)
Mouse
(130)
Rat
(1)
Transgenic Mouse
(1)
All Species
Showing Publications 1 - 10 of 134. Show All 134 Publications.
Publications using DY413 Applications Species
W Chang, H Lv, L Tan, Z Gao, P Liu, D Qin, W Zhang, Y Xu Downregulation of deubiquitinating enzyme USP25 promotes the development of allergic rhinitis by enhancing TSLP signaling in the nasal epithelium Molecular Medicine Reports, 2022;26(5):. 2022 [PMID: 36177892] (Mouse) Mouse
M Fujimoto, M Yokoyama, M Kiuchi, H Hosokawa, A Nakayama, N Hashimoto, I Sakuma, H Nagano, K Yamagata, F Kudo, I Manabe, E Lee, R Hatano, A Onodera, K Hirahara, K Yokote, T Miki, T Nakayama, T Tanaka Liver group 2 innate lymphoid cells regulate blood glucose levels through IL-13 signaling and suppression of gluconeogenesis Nature Communications, 2022;13(1):5408. 2022 [PMID: 36109558] (Mouse) Mouse
J Won, A Jo, CH Gil, S Kim, H Shin, H Jik Kim Inhaled delivery of recombinant interferon-lambda restores allergic inflammation after development of asthma by controlling Th2- and Th17-cell-mediated immune responses International immunopharmacology, 2022;112(0):109180. 2022 [PMID: 36030690] (Mouse) Mouse
Y Zhang, L Zhu, J Hong, C Chen Extracellular matrix of early pulmonary fibrosis modifies the polarization of alveolar macrophage International immunopharmacology, 2022;111(0):109179. 2022 [PMID: 36029666] (Mouse) Mouse
T Ashikari, M Hachisu, K Nagata, D Ando, Y Iizuka, N Ito, K Ito, Y Ikeda, H Matsubara, T Yashiro, K Kasakura, C Nishiyama Salicylaldehyde Suppresses IgE-Mediated Activation of Mast Cells and Ameliorates Anaphylaxis in Mice International Journal of Molecular Sciences, 2022;23(15):. 2022 [PMID: 35955959] (Mouse) Mouse
CR Morris, A Habibovic, CM Dustin, C Schiffers, MC Lin, JL Ather, YMW Janssen-He, ME Poynter, O Utermohlen, M Krönke, A van der Vl Macrophage-intrinsic DUOX1 contributes to type 2 inflammation and mucus metaplasia during allergic airway disease Mucosal Immunology, 2022;0(0):. 2022 [PMID: 35654836] (Mouse) Mouse
D Chen, J Li, Y Huang, P Wei, W Miao, Y Yang, Y Gao Interleukin 13 promotes long-term recovery after ischemic stroke by inhibiting the activation of STAT3 Journal of Neuroinflammation, 2022;19(1):112. 2022 [PMID: 35578342] (Mouse) Mouse
AD Friedrich, J Leoni, ML Paz, DH González M Lipoteichoic Acid from Lacticaseibacillus rhamnosus GG Modulates Dendritic Cells and T Cells in the Gut Nutrients, 2022;14(3):. 2022 [PMID: 35277082] (Mouse) Mouse
S Wang, L Gong, Y Mo, J Zhang, Z Jiang, Z Tian, C Shao Resveratrol attenuates inflammation and apoptosis through alleviating endoplasmic reticulum stress via Akt/mTOR pathway in fungus-induced allergic airways inflammation International immunopharmacology, 2021;103(0):108489. 2021 [PMID: 34968999] (Mouse) Mouse
Y Wu, E Li, M Knight, G Adeniyi-Ip, LZ Song, AR Burns, AC Gazzinelli, R Fujiwara, ME Bottazzi, JE Weatherhea Transient Ascaris suum larval migration induces intractable chronic pulmonary disease and anemia in mice PloS Neglected Tropical Diseases, 2021;15(12):e0010050. 2021 [PMID: 34914687] (Mouse) Mouse
Show All 134 Publications.

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Product General Protocols

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Bioinformatics Tool for IL-13 (DY413)

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Blogs on IL-13.

Signal Transducer and Activator of Transcription STAT6: More than a Player in Allergic Inflammation
By Jamshed Arslan, Pharm. D., PhD. What is STAT6?The cellular pathway comprising tyrosine kinase Janus Kinase (JAK) and the transcription factor STAT connect extracellular signals from various cytokines, hormones an...  Read full blog post.

FLICE, FLICE, baby
Cell death via apoptosis is a fundamental cellular function triggered by the cell death receptor family and their ligands which signal through downstream adaptor molecules and the caspase protease family. All caspases exist in a precursor form compose...  Read full blog post.

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Bioinformatics

Gene Symbol Il13