Mouse IL-13 DuoSet ELISA, 15 Plate

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

Mouse IL-13 DuoSet ELISA, 15 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Il13

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using
DY413 in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse IL-13 DuoSet ELISA, 15 Plate

  • ALRHMGC116789
  • BHR1interleukin-13
  • IL13
  • IL-13
  • IL-13MGC116788
  • interleukin 13
  • MGC116786
  • NC30
  • P600

Background

IL-13 (Interleukin-13) plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. IL-13 suppresses the production of proinflammatory cytokines and other cytotoxic substances by macrophages, fibroblasts, and endothelial cells. It promotes B cell activation, immunoglobulin class switching to IgE, and the upregulation of CD23/Fc epsilon RII. IL-13 signals through a receptor complex containing IL-13 R alpha 1 and IL-4 R alpha. This complex also functions as the type 2 IL-4 receptor. IL-13 R alpha 2 binds IL-13 and prevents IL-13 from signaling through the IL-13 R alpha 1/IL-4 R alpha complex. IL-13-bound IL-13 R alpha 2 can directly promote tumor cell invasiveness and the development of tissue fibrosis.

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Publications for IL-13 (DY413)(141)

We have publications tested in 4 confirmed species: Human, Mouse, Rat, Transgenic Mouse.

We have publications tested in 1 application: ELISA Capture.


Filter By Application
ELISA Capture
(1)
All Applications
Filter By Species
Human
(1)
Mouse
(138)
Rat
(1)
Transgenic Mouse
(2)
All Species
Showing Publications 1 - 10 of 141. Show All 141 Publications.
Publications using DY413 Applications Species
Kaneki, M;Ohira, C;Takahashi, M;Iwashita, N;Takagi, Y;Nagane, M;Uchiyama, J;Fukuyama, T; Therapeutic potential of ozone water treatment in alleviating atopic dermatitis symptoms in mouse models: Exploring its bactericidal and direct anti-inflammatory properties International immunopharmacology 2023-09-14 [PMID: 37716162] (Mouse) Mouse
Maggi, L;Camelo, GMA;Rocha, IC;Pereira Alves, W;Moreira, JMP;Almeida Pereira, T;Tafuri, WL;Rabelo, ÉML;Correa, A;Ecco, R;Negrão-Corrêa, DA; Role of the IL-33/ST2 Activation Pathway in the Development of the Hepatic Fibrosis Induced by Schistosoma mansoni Granulomas in Mice International journal of molecular sciences 2023-06-16 [PMID: 37373379] (Mouse) Mouse
Sagar, S;Faizan, MI;Chaudhary, N;Singh, V;Singh, P;Gheware, A;Sharma, K;Azmi, I;Singh, VP;Kharya, G;Mabalirajan, U;Agrawal, A;Ahmad, T;Sinha Roy, S; Obesity impairs cardiolipin-dependent mitophagy and therapeutic intercellular mitochondrial transfer ability of mesenchymal stem cells Cell death & disease 2023-05-13 [PMID: 37173333] (Mouse) Mouse
K Nagata, S Araumi, D Ando, N Ito, M Ando, Y Ikeda, M Takahashi, S Noguchi, Y Yasuda, N Nakano, T Ando, M Hara, T Yashiro, M Hachisu, C Nishiyama Kaempferol Suppresses the Activation of Mast Cells by Modulating the Expression of FcepsilonRI and SHIP1 International Journal of Molecular Sciences, 2023-03-22;24(6):. 2023-03-22 [PMID: 36983066] (Mouse) Mouse
H Tallima, R El Ridi Increased hepatic interleukin-1, arachidonic acid, and reactive oxygen species mediate the protective potential of peptides shared by gut cysteine peptidases against Schistosoma mansoni infection in mice PloS Neglected Tropical Diseases, 2023-03-15;17(3):e0011164. 2023-03-15 [PMID: 36920999] (Mouse) Mouse
J Xiao, X Chen, W Liu, W Qian, K Bulek, L Hong, W Miller-Lit, X Li, C Liu TRAF4 is crucial for the propagation of ST2+ memory Th2 cells in IL-33-mediated type 2 airway inflammation bioRxiv : the preprint server for biology, 2023-02-12;0(0):. 2023-02-12 [PMID: 36798382] (Mouse) Mouse
W Chang, H Lv, L Tan, Z Gao, P Liu, D Qin, W Zhang, Y Xu Downregulation of deubiquitinating enzyme USP25 promotes the development of allergic rhinitis by enhancing TSLP signaling in the nasal epithelium Molecular Medicine Reports, 2022-09-30;26(5):. 2022-09-30 [PMID: 36177892] (Mouse, Transgenic Mouse) Mouse, Transgenic Mouse
M Fujimoto, M Yokoyama, M Kiuchi, H Hosokawa, A Nakayama, N Hashimoto, I Sakuma, H Nagano, K Yamagata, F Kudo, I Manabe, E Lee, R Hatano, A Onodera, K Hirahara, K Yokote, T Miki, T Nakayama, T Tanaka Liver group 2 innate lymphoid cells regulate blood glucose levels through IL-13 signaling and suppression of gluconeogenesis Nature Communications, 2022-09-15;13(1):5408. 2022-09-15 [PMID: 36109558] (Mouse) Mouse
X Xiong, C Yang, WQ He, J Yu, Y Xin, X Zhang, R Huang, H Ma, S Xu, Z Li, J Ma, L Xu, Q Wang, K Ren, XS Wu, CR Vakoc, J Zhong, G Zhong, X Zhu, Y Song, HB Ruan, Q Wang Sirtuin 6 maintains epithelial STAT6 activity to support intestinal tuft cell development and type 2 immunity Nature Communications, 2022-09-03;13(1):5192. 2022-09-03 [PMID: 36057627] (Mouse) Mouse
J Won, A Jo, CH Gil, S Kim, H Shin, H Jik Kim Inhaled delivery of recombinant interferon-lambda restores allergic inflammation after development of asthma by controlling Th2- and Th17-cell-mediated immune responses International immunopharmacology, 2022-08-27;112(0):109180. 2022-08-27 [PMID: 36030690] (Mouse) Mouse
Show All 141 Publications.

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Signal Transducer and Activator of Transcription STAT6: More than a Player in Allergic Inflammation
By Jamshed Arslan, Pharm. D., PhD. What is STAT6?The cellular pathway comprising tyrosine kinase Janus Kinase (JAK) and the transcription factor STAT connect extracellular signals from various cytokines, hormones an...  Read full blog post.

FLICE, FLICE, baby
Cell death via apoptosis is a fundamental cellular function triggered by the cell death receptor family and their ligands which signal through downstream adaptor molecules and the caspase protease family. All caspases exist in a precursor form compose...  Read full blog post.

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Bioinformatics

Gene Symbol Il13