TIM-3 Antibody


Western Blot: TIM-3 Antibody [NB100-56422] - Analysis of TIM-3 in A) mouse and B) rat kidney cell lysate using this antibody at 2 ug/ml.

Product Details

Reactivity MuSpecies Glossary
Applications WB
0.5 mg/ml

Order Details

TIM-3 Antibody Summary

A portion of amino acids 100-200 of mouse TIM-3 protein were used as the immunogen.
The NCBI accession number for TIM-3 is AAL35776.
Protein G purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS containing 0.05% BSA
0.05% Sodium Azide
0.5 mg/ml
Protein G purified

Reactivity Notes

Predicted to react with Rat (79%).

Alternate Names for TIM-3 Antibody

  • CD366
  • FLJ14428
  • HAVCR2
  • HAVcr-2
  • hepatitis A virus cellular receptor 2
  • kidney injury molecule-3
  • T cell immunoglobulin mucin 3
  • T cell immunoglobulin mucin-3
  • T-cell immunoglobulin and mucin domain-containing protein 3
  • TIM 3
  • TIM3 T-cell membrane protein 3
  • TIM3
  • Tim-3
  • TIMD-3
  • TIMD3KIM-3


Official Gene Symbol HAVCR2 Gene ID 84868(Human) Gene Map Locus 5q33.3(Human) HAVCR2 is a 281 A.A Type-1 Th1 specific cell surface glycoprotein expressed on terminally differentiated CD4+Th1 and CD8+Tc1 cells. It consists of an IgV-region like domain and a mucin-like domain in the extracellular region and a conserved Tyrosine phosphorylation motif in the cytoplasmic region. HAVCR2 regulates macrophage activation thereby down regulating aggressive Th-1 mediated immune responses and facilitates in the development of immune tolerance. It plays an important role in the induction of autoimmune diseases by regulating macrophage activation. Pathological significance of HAVCR2 has been attributed to Experimental autoimmune encephalomyelitis (EAE), a Th-1 dependent autoimmune disease.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

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Bioinformatics Tool for TIM-3 Antibody (NB100-56422)

Discover related pathways, diseases and genes to TIM-3 Antibody (NB100-56422). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for TIM-3 Antibody (NB100-56422)

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Research Areas for TIM-3 Antibody (NB100-56422)

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Blogs on TIM-3.

TIM-3, a critical immune checkpoint in HIV research
CD4+ T-helper cells (Th) are the white blood lymphocytes expressing surface glycoprotein antigen CD4. These T-helper cells play an important role in the adaptive immune system by releasing T cell cytokines that help other immune cells to suppress o...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol HAVCR2

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