TIM-3 Products

Antibodies
TIM-3 Antibody
TIM-3 Antibody
AF2365
Species: Hu
Applications: WB, Flow, CyTOF-ready
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
TIM-3 Antibody (2E2)
TIM-3 Antibody (2E2)
NBP2-45933
Species: Hu
Applications: IHC, IHC-P
Host: Mouse Monoclonal
Lysates
TIM-3 Overexpression Lysate ( ...
TIM-3 Overexpression Lysate (Native)
NBL1-11452
Applications: WB
Proteins
Recombinant Human TIM-3 Prote ...
Recombinant Human TIM-3 Protein
H00084868-P01
Species: Hu
Applications: WB, ELISA, PA
TIM-3 Recombinant Protein Ant ...
TIM-3 Recombinant Protein Antigen
NBP2-55701PEP
Species: Hu
Applications: B/N, Ctrl
Recombinant Human TIM-3 Prote ...
Recombinant Human TIM-3 Protein
NBP2-52358
Species: Hu
Applications: PAGE
RNAi
TIM-3 RNAi
TIM-3 RNAi
H00084868-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

CD4 (MIM 186940)-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.[supplied by OMIM]

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Mouse
Product By Gene ID 84868
Alternate Names
  • CD366
  • TIM3 T-cell membrane protein 3
  • TIM 3
  • TIMD-3
  • T cell immunoglobulin mucin-3
  • HAVcr-2
  • T cell immunoglobulin mucin 3
  • Tim-3
  • kidney injury molecule-3
  • FLJ14428
  • TIMD3KIM-3
  • T-cell immunoglobulin and mucin domain-containing protein 3
  • hepatitis A virus cellular receptor 2

Research Areas for TIM-3

Find related products by research area and learn more about each of the different research areas below.

Immunology
Innate Immunity

PTMs for TIM-3

Learn more about PTMs related to TIM-3.

Phosphorylation
Glycosylation
Cleavage
Dephosphorylation

Bioinformatics Tool for TIM-3

Discover related pathways, diseases and genes to TIM-3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related TIM-3 Blog Posts

Check out the latest blog posts on TIM-3.
TIM-3, a critical immune checkpoint in HIV research
CD4+ T-helper cells (Th) are the white blood lymphocytes expressing surface glycoprotein antigen CD4. These T-helper cells play an important role in the adaptive immune system by releasing T cell cytokines that help other immune cells to suppress o...    Read more.
Read more TIM-3 related blogs.