Spectrin beta 3 Antibody [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Biotin

Spectrin beta 3 Antibody [Biotin] Summary

Immunogen
The epitope recognized by this antibody maps to a region between residues 2150 and 2200 of Spectrin beta 3 using the numbering given in entry NP_008877.1
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SPTBN2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 2.5-5 ug/ml
  • Immunoprecipitation 2-5 ug/mg
Application Notes
This Spectrin beta 3 antibody is useful for Immunoprecipitation, Immunocytochemistry/Immunofluorescence and Immunohistochemistry paraffin embedded sections. It is not recommended for Western blot analysis.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
271 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Readout System

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Spectrin beta 3 Antibody [Biotin]

  • beta-III Spectrin
  • glutamate transporter EAAT4-associated protein 41
  • GTRAP41
  • KIAA0302
  • SCA5
  • SCAR14
  • Spectrin beta 3
  • spectrin beta chain, brain 2
  • Spectrin beta III
  • spectrin, beta, non-erythrocytic 2
  • Spectrin, non-erythroid beta chain 2
  • spinocerebellar ataxia 5
  • SPTBN2

Background

Mutations in spectrins are a previously unknown cause of ataxia and neurodegenerative disease that affect membrane proteins involved in glutamate signaling. Spectrin-beta IIIs have been recognized as ataxia disease genes and their mutations cause spinocerebellar ataxia type 5 (SCA5).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol SPTBN2
Entrez