The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.
Synthetic peptides corresponding to SF1/Steroidogenic Factor 1 The peptide sequence was selected from the middle region of SF1/Steroidogenic Factor 1. Peptide sequence SLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGRA. The peptide sequence for this immunogen was taken from within the described region.
Test in a species/application not listed above to receive a full credit towards a future purchase.
Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID : 30529237). In Simple Western internal validation: Human fetal adrenal glands as sample; separated by size; antibody dilution of 1:50; observed molecular weight was ~56 kDa; matrix was 12-230 kDa; detected by Chemiluminescence.
52 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Read Publications using NBP1-52823 in the following applications:
Use in Mouse reported in scientific literature (PMID:34183774)
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS, 2% Sucrose
0.09% Sodium Azide
Alternate Names for SF-1/NR5A1/Steroidogenic Factor 1 Antibody
Adrenal 4-binding protein
FTZ1adrenal 4 binding protein
FTZF1nuclear receptor AdBP4
Fushi tarazu factor homolog 1
Nuclear receptor subfamily 5 group A member 1
nuclear receptor subfamily 5, group A, member 1
SF1steroidogenic factor 1
Steroid hormone receptor Ad4BP
NR5A1 is an important regulator of steroidogeneisis which is present in human skin and its appendages. It plays a role in regulating p450scc expression with TReP-132 and CBP/p300. The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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