SF-1/NR5A1/Steroidogenic Factor 1 Products

Description

Steroidogenic factor 1 (SF-1), a NR5 Fushi Tarazu-Like Receptor, has been shown to affect sexual differentiation, steroid metabolism, and neural development. SF-1 binds as a monomer and regulates all steroidogenic p450 genes, Mullerian inhibiting substance, the gonadotrophins, the ACTH receptor, oxytocin, nuclear receptor DAX-1, and several other genes. Four alternatively spliced isoforms of SF-1 have been isolated in mice, and they differ at the N and C termini but are identical in the DNA-binding domain. SF-1 expression has been documented in human brain, adrenal, spleen, liver, heart, ovary, testis, and placenta. ESTs have been isolated from human tissue libraries, including cancerous adrenal and normal lung and testis.

Bioinformatics

Product By Gene ID	2516
Alternate Names	AD4BP AD4BPSTF-1 Adrenal 4-binding protein ELP FTZ1adrenal 4 binding protein FTZF1 FTZF1nuclear receptor AdBP4 Fushi tarazu factor homolog 1 NR5A1 Nuclear receptor subfamily 5 group A member 1 nuclear receptor subfamily 5, group A, member 1 SF1 SF-1 SF-1POF7 SF1steroidogenic factor 1 Steroid hormone receptor Ad4BP steroidogenic factor-1

Research Areas for SF-1/NR5A1/Steroidogenic Factor 1

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Cell Biology