SBEM Antibody - BSA Free

Immunohistochemistry-Paraffin: SBEM Antibody [NBP1-92366] - Staining in human breast and liver tissues . Corresponding MUCL1 RNA-seq data are presented for the same tissues.

Western Blot: SBEM Antibody [NBP1-92366] - Analysis of SBEM in KPL4 whole cell lysate (left) and MUCL1 (SBEM) siRNA (right) using anti-SBEM antibody. Image submitted by a verified customer review

Immunohistochemistry-Paraffin: SBEM Antibody [NBP1-92366] - Immunohistochemical staining of human liver shows no positivity in hepatocytes as expected.

Immunohistochemistry-Paraffin: SBEM Antibody [NBP1-92366] - Staining of human breast cancer shows moderate to strong cytoplasmic positivity in tumor cells.

Immunohistochemistry-Paraffin: SBEM Antibody [NBP1-92366] - Staining of human breast shows moderate to strong cytoplasmic positivity in glandular cells.

Immunohistochemistry-Paraffin: SBEM Antibody [NBP1-92366] - Staining of human tonsil shows no positivity in non-germinal center cells as expected.

Staining of human tonsil shows no positivity in non-germinal center cells as expected.

• Reactivity: Hu
• Applications: WB, IHC, Mycoplasma
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

SBEM Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit SBEM Antibody - BSA Free (NBP1-92366) is a polyclonal antibody validated for use in IHC and WB. Anti-SBEM Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: AQNPTTAAPADTYPATGPADDEAPDAETTAAATTA
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MUCL1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
  • Knockdown Validated
  • Western Blot Validated from a verified customer review
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  SBEM Protein (NBP1-92366PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for SBEM Antibody - BSA Free

• mucin-like 1
• mucin-like protein 1
• Protein BS106
• SBEMSmall breast epithelial mucin

Background

SBEM may play a role as marker for the diagnosis of metastatic breast cancer

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SBEM Antibody (NBP1-92366)(2)

Publications using NBP1-92366

• Abdulla M, Traiki TB, Vaali-Mohammed MA et al. Targeting MUCL1 protein inhibits cell proliferation and EMT by deregulating beta catenin and increases irinotecan sensitivity in colorectal cancer International journal of oncology 2022-03-01 [PMID: 35059735] (WB, Human)
• Kim J, Choi H. The mucin protein MUCL1 regulates melanogenesis and melanoma genes in a manner dependent on threonine content British Journal of Dermatology 2022-03-01 [PMID: 34545566]

Review for SBEM Antibody (NBP1-92366) (1)

Average Rating: 3

(Based on 1 review)

We have 1 review tested in 1 species: Human.

reviewed by: Verified Customer WB Human 04/02/2015

Summary

• Application: Western Blot
• Sample Tested: KPL4 whole cell lysat
• Species: Human

Bioinformatics

• Gene Symbol: MUCL1