SAT1 Antibody


Western Blot: SAT1 Antibody [NB110-41622] - Detection of SAT1 in human SAT1 transfected lysate.
Immunohistochemistry: SAT1 Antibody [NB110-41622] - IHC analysis of SAT1 in mouse seminal vesical (left) and prostate (right) usind DAB with hematoxylin counterstain,

Product Details

Reactivity Hu, Mu, Rt, Po, Bv, Ch, Gt, XpSpecies Glossary
Applications WB, IHC, IHC-P
1.0 mg/ml

SAT1 Antibody Summary

A synthetic peptide made to a C-terminal region within residues 100-171 of human SAT1. [Swiss-Prot# P21673]
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Western Blot 1:500-1:1000
  • Immunohistochemistry 1:100
  • Immunohistochemistry-Paraffin 1:100
Application Notes
This SAT1 antibody is useful for Western Blot, and Immunohistochemistry paraffin embedded sections. In Western Blot analysis on transfected lysates a band is seen at ~27 kDa. In IHC-P, strong staining was observed in the cytoplasm with some weak nuclear staining in mouse seminal vesical and prostate tissue. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
27 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
SAT1 Overexpression Lysate
Control Peptide
SAT1 Peptide (NB110-41622PEP)
Read Publications using
NB110-41622 in the following applications:

  • WB
    2 publications

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Zebrafish (86%).

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.02% Sodium Azide
1.0 mg/ml
Immunogen affinity purified

Alternate Names for SAT1 Antibody

  • DC21
  • diamine acetyltransferase 1
  • diamine N-acetyltransferase 1
  • EC
  • KFSD
  • Polyamine N-acetyltransferase 1
  • Putrescine acetyltransferase
  • SAT
  • Spermidine/spermine N(1)-acetyltransferase 1
  • spermidine/spermine N1-acetyltransferase 1
  • spermidine/spermine N1-acetyltransferase alpha
  • spermidine/spermine N1-acetyltransferase
  • SSAT-1


SAT1 or spermidine/spermine N(1)-acetyltransferase 1 (also called SSAT, diamine acetyltransferase 1 and putrescine acetyltransferase) is a homodimeric cytoplasmic enzyme which belongs to acetyltransferase family and catalyzes acetylation of polyamines. SAT1's substrate specificity order is: norspermidine = spermidine >spermine > N(1)-acetylspermine > putrescine, and its activity is highly regulated that allows a fine attenuation of the intracellular polyamines concentrations via acetylation or polyamine export. Polyamines such as putrescine, spermidine and spermine are implicated in the regulation of cellular growth/proliferation (increased levels leads to cancer progression) and their levels are controlled by several catabolic enzymes which includes such as SAT1, APAO (acetylpolyamine oxidase) and SMO (spermine oxidase). Enhanced SSAT expression has been shown to be associated with apoptosis in cancer cells and SSAT was shown to decrease the expression of anti-apoptosis-related signaling proteins AKT and mTOR. SAT1 has also been implicated in the neurobiology of suicide and decreased SAT1 expression has been observed in several brain regions in suicide completers. Defects in SAT1 may be a cause of keratosis follicularis spinulosa decalvans X-linked (KFSDX).


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
Species: Hu, Mu, Po, Bv, Rb
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
Species: Hu
Applications: WB, IHC, IHC-P
Species: Hu
Applications: WB, ICC/IF
Species: Hu
Species: Hu
Applications: IHC, IHC-P
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, ELISA
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P, IP
Species: Hu
Applications: WB, Flow, CyTOF-ready
Species: Hu, Mu, Rt, Bv
Applications: WB, ELISA
Species: Hu, Rt
Applications: ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB, Flow, IHC, IHC-P
Species: Hu, Mu, Rt, Po, Bt, Bv, Ca, Eq, Ha, Pm, Rb
Applications: ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt, Po, Bv, Ch, Gt, Xp
Applications: WB, IHC, IHC-P

Publications for SAT1 Antibody (NB110-41622)(3)

Reviews for SAT1 Antibody (NB110-41622) (0)

There are no reviews for SAT1 Antibody (NB110-41622). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Video Protocols

WB Video Protocol

FAQs for SAT1 Antibody (NB110-41622). (Showing 1 - 1 of 1 FAQs).

  1. I need to radiolabel (iodinate) the SAT1 antibody. Which one should I use?
    • I would recommend NB110-41622 for you as it is a well validated antibody with very clean QC validation data, multiple applications/broad species reactivity. Additionally, this antibody has been cited by Liao et al. in <a href="" target="_blank">The Journal of Biological Chemistry</a> 2009;284(12):8174-8184.

Control Lysate(s)

Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor 350 NB110-41622AF350
Alexa Fluor 405 NB110-41622AF405
Alexa Fluor 488 NB110-41622AF488
Alexa Fluor 532 NB110-41622AF532
Alexa Fluor 594 NB110-41622AF594
Alexa Fluor 647 NB110-41622AF647
Alexa Fluor 700 NB110-41622AF700
Alexa Fluor 750 NB110-41622AF750
Biotin NB110-41622B
DyLight 350 NB110-41622UV
DyLight 405 NB110-41622V
DyLight 488 NB110-41622G
DyLight 550 NB110-41622R
DyLight 594 NB110-41622DL594
DyLight 650 NB110-41622C
DyLight 680 NB110-41622FR
DyLight 755 NB110-41622IR
FITC NB110-41622F
HRP NB110-41622H
Janelia Fluor 549 NB110-41622JF549
Janelia Fluor 646 NB110-41622JF646

Additional SAT1 Products

Bioinformatics Tool for SAT1 Antibody (NB110-41622)

Discover related pathways, diseases and genes to SAT1 Antibody (NB110-41622). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for SAT1 Antibody (NB110-41622)

Discover more about diseases related to SAT1 Antibody (NB110-41622).

Pathways for SAT1 Antibody (NB110-41622)

View related products by pathway.

PTMs for SAT1 Antibody (NB110-41622)

Learn more about PTMs related to SAT1 Antibody (NB110-41622).

Research Areas for SAT1 Antibody (NB110-41622)

Find related products by research area.

Blogs on SAT1

There are no specific blogs for SAT1, but you can read our latest blog posts.
Coronavirus Brochure

Customers Who Bought This Also Bought

Contact Information

Learn the difference between western blot and simple western

Product PDFs


Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.


Review this Product

Be the first to review our SAT1 Antibody and receive a gift card or discount.


Gene Symbol SAT1