S100B Antibody (S100B/1012) [PerCP]

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Product Details

Summary
Reactivity Hu, Mu, Rt, BvSpecies Glossary
Applications Flow
Clone
S100B/1012
Clonality
Monoclonal
Host
Mouse
Conjugate
PerCP

Order Details

S100B Antibody (S100B/1012) [PerCP] Summary

Immunogen
Recombinant full-length human S100B protein
Localization
Cytoplasmic
Marker
Astrocyte and Melanoma Marker
Specificity
The specificity of this monoclonal antibody to S100B was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta -chain (i.e. in S-100A and S-100B) but not on the alpha-chain of S-100 (i.e. in S-100A and S100A0). This antibody can be used to localize S-100A and S-100B in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lip ocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell -derived tumors express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S -100 protein
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
S100B
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for S100B Antibody (S100B/1012) [PerCP]

  • beta (neural)
  • NEF
  • S100 beta
  • S100 calcium binding protein B
  • S100 calcium-binding protein B
  • S100 calcium-binding protein, beta (neural)
  • S-100 calcium-binding protein, beta chain, 10protein S100-B
  • S-100 protein beta chain
  • S-100 protein subunit beta
  • S100
  • S100B
  • S100beta

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for S100B Antibody (NBP2-59619PCP) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-59619AF350
Alexa Fluor 405 NBP2-59619AF405
Alexa Fluor 488 NBP2-59619AF488
Alexa Fluor 532 NBP2-59619AF532
Alexa Fluor 594 NBP2-59619AF594
Alexa Fluor 647 NBP2-59619AF647
Alexa Fluor 700 NBP2-59619AF700
Alexa Fluor 750 NBP2-59619AF750
Allophycocyanin NBP2-59619APC
Biotin NBP2-59619B
DyLight 350 NBP2-59619UV
DyLight 405 NBP2-59619V
DyLight 488 NBP2-59619G
DyLight 550 NBP2-59619R
DyLight 594 NBP2-59619DL594
DyLight 650 NBP2-59619C
DyLight 680 NBP2-59619FR
DyLight 755 NBP2-59619IR
FITC NBP2-59619F
HRP NBP2-59619H
Janelia Fluor 549 NBP2-59619JF549
Janelia Fluor 646 NBP2-59619JF646
PE NBP2-59619PE
PerCP NBP2-59619PCP

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Blogs on S100B.

Role of GFAP in astrocytes: Lessons from induced pluripotent stem cells in Alexander disease patients
By Michalina Hanzel, PhDAlexander disease is a progressive and fatal neurological disease with phenotypes ranging from myelination abnormalities, gait ataxia and megalencephaly to predisposition to seizures. It is an...  Read full blog post.

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Bioinformatics

Gene Symbol S100B