Melan-A/MART-1 Antibody (A19-P)

Images

 
Immunohistochemistry-Paraffin: Melan-A/MART-1 Antibody (A19-P) [NBP1-30151] - Confocal microscopy image of human fetal inner ear tisue section stained with Melan-A antibody (green), 1:200 dilution, incubated over night. ...read more
Immunohistochemistry-Paraffin: Melan-A/MART-1 Antibody (A19-P) [NBP1-30151] - Human tissue (4 um section) stained with anti - Melan A monospecific clonal antibody.

Product Details

Summary
Reactivity Hu, Mu, CaSpecies Glossary
Applications ICC/IF, IHC, IHC-P
Clone
A19-P
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Melan-A/MART-1 Antibody (A19-P) Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Peptide derived from C-terminal sequence of human Melan-A/MART-1. Antibody recognizes the epitope between Glu105 - Pro115.
Epitope
Glu105 - Pro115
Specificity
This antibody is specific for the C terminal portions of Melan-A
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
MLANA
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry 1:100 - 1:200
  • Immunohistochemistry-Paraffin 1:100 - 1:200
Reviewed Applications
Read 4 Reviews rated 4.8
using
NBP1-30151 in the following applications:

Publications
Read Publications using
NBP1-30151 in the following applications:

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 26547111). Use in Canine reported in secitific publication PMID: 32423311

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
20mM Tris-HCl (pH 8.0) and 20mg/ml BSA
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

This antibody is immunoaffinity purified with immunogenic peptide as a ligand.

Alternate Names for Melan-A/MART-1 Antibody (A19-P)

  • Antigen LB39-AA
  • Antigen SK29-AA
  • Mart 1 Melan A
  • MART-1
  • MART1MART-1
  • MelanA
  • Melan-A
  • melanoma antigen recognized by T-cells 1
  • MLANA
  • Protein Melan-A

Background

MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Melan-A/MART-1 Antibody (NBP1-30151)(15)

We have publications tested in 3 confirmed species: Human, Mouse, Canine.

We have publications tested in 3 applications: ICC/IF, IHC, IHC-P.


Filter By Application
ICC/IF
(1)
IHC
(5)
IHC-P
(6)
All Applications
Filter By Species
Human
(6)
Mouse
(5)
Canine
(1)
All Species
Showing Publications 1 - 10 of 15. Show All 15 Publications.
Publications using NBP1-30151 Applications Species
Eshiba S, Namiki T, Mohri Y Et al. Stem cell spreading dynamics intrinsically differentiate acral melanomas from nevi Cell reports Aug 3 2021 [PMID: 34348144]
van Beelen ESA, van der Valk WH, de Groot JCMJ et al. Migration and fate of vestibular melanocytes during the development of the human inner ear Dev Neurobiol Oct 19 2020 [PMID: 33075185] (IHC, Human) IHC Human
Nakano S, Abe Y, Nakajima K et al. Establishment of a mouse model for post-inflammatory hyperpigmentation Pigment Cell Melanoma Res Jul 4 2020 [PMID: 32623834] (IHC) IHC
Rahman H, Kumar D, Liu T et al. Aspirin protects melanocytes and keratinocytes against UVB-induced DNA damage in vivo J. Invest. Dermatol. Jun 19 2020 [PMID: 32569596]
Touil Y, Segaoula Z, Thuru X et al. Aggressiveness potential of spontaneous canine mucosal melanoma can dictate distinct cancer stem cell compartment behaviors in regard to their initial size and expansion abilities Stem Cells Dev. May 18 2020 [PMID: 32423311] (IHC, Canine) IHC Canine
Boukhedouni N, Martins C, Darrigade AS et al. Type-1 cytokines regulate MMP-9 production and E-cadherin disruption to promote melanocyte loss in vitiligo JCI Insight Jun 4 2020 [PMID: 32369451] (IHC-P, Human) IHC-P Human
Pai CS, Huang JT, Lu X et al. Clonal Deletion of Tumor-Specific T Cells by Interferon-g Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade Immunity Feb 19 2019 [PMID: 30737146] (IHC, Mouse) IHC Mouse
Kimeswenger S, Sterniczky B, kramer A et al. Impact of infrared radiation on UVB-induced skin tumourigenesis in wild type C57BL/6 mice. Photochem. Photobiol. Sci. Oct 24 2018 [PMID: 30357250] (Mouse) Mouse
De Luca DA, Sterniczky B, Kimeswenger S et al. Ultraviolet radiation induces Melan-A-expressing cells in interfollicular epidermis in wild-type mice Arch. Dermatol. Res. May 17 2018 [PMID: 29774387] (IHC-P, Mouse) IHC-P Mouse
Cassidy PB, Liu T, Florell SR et al. A phase II randomized placebo-controlled trial of oral N-acetylcysteine for protection of melanocytic nevi against UV-induced oxidative stress in vivo Cancer Prev Res (Phila). 2016 Dec 04 [PMID: 27920018] (IHC-P, Human) IHC-P Human
Show All 15 Publications.

Reviews for Melan-A/MART-1 Antibody (NBP1-30151) (4) 4.84

Average Rating: 4.8
(Based on 4 reviews)
We have 4 reviews tested in 2 species: Human, Mouse.

Reviews using NBP1-30151:
Filter by Applications
Immunohistochemistry-Paraffin
(2)
Immunocytochemistry
(2)
All Applications
Filter by Species
Human
(3)
Mouse
(1)
All Species
Images Ratings Applications Species Date Details
Immunohistochemistry-Paraffin Melan-A/MART-1 NBP1-30151
Enlarge
5
reviewed by:
Edward van Beelen
Immunohistochemistry-Paraffin Human 10/30/2019
View

Summary

ApplicationImmunohistochemistry-Paraffin
Sample Testedhuman fetal inner ear
SpeciesHuman
LotDB050-01-06B
Immunocytochemistry Melan-A/MART-1 NBP1-30151
Enlarge
4
reviewed by:
H Locher
Immunocytochemistry Mouse 09/02/2013
View

Summary

ApplicationImmunocytochemistry
Sample TestedMouse melanocyte cell line
SpeciesMouse
Immunocytochemistry Melan-A/MART-1 NBP1-30151
Enlarge
5
reviewed by:
H Locher
Immunocytochemistry Human 09/02/2013
View

Summary

ApplicationImmunocytochemistry
Sample TestedHuman hair follicle culture
SpeciesHuman
Immunohistochemistry-Paraffin Melan-A/MART-1 NBP1-30151
Enlarge
5
reviewed by:
H Locher
Immunohistochemistry-Paraffin Human 09/02/2013
View

Summary

ApplicationImmunohistochemistry-Paraffin
Sample TestedHuman adult facial skin
SpeciesHuman

Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for Melan-A/MART-1 Antibody (NBP1-30151) (0)

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Secondary Antibodies

 

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Bioinformatics Tool for Melan-A/MART-1 Antibody (NBP1-30151)

Discover related pathways, diseases and genes to Melan-A/MART-1 Antibody (NBP1-30151). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for Melan-A/MART-1 Antibody (NBP1-30151)

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Recent Reviews

4.8
5
3
4
1
3
0
2
0
1
0

Edward van Beelen
10/30/2019
Application: Immunohistochemistry-Paraffin
Species: Human

H Locher
09/02/2013
Application: Immunocytochemistry
Species: Mouse

H Locher
09/02/2013
Application: Immunocytochemistry
Species: Human

Bioinformatics

Gene Symbol MLANA
Entrez
Uniprot