RBFOX3/NeuN Antibody (1B7) [DyLight 405]


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Product Details

Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Flow, ICC/IF, IHC-Fr, IHC-P
DyLight 405

RBFOX3/NeuN Antibody (1B7) [DyLight 405] Summary

N-terminal 100 amino acids of human FOX3 as expressed in and purified from E. coli
Nucleus. Cytoplasm.
Neuronal Marker
Protein G purified
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  • Western Blot
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
Application Notes
This RBFOX3/Neun (1B7) antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot, where bands can be seen at 46 and 48 kDa. Use in IHC-frozen sections was reported in the scientific literature (PMID: 23776455).

Reactivity Notes

Human, bovine, porcine, mouse, rat and other mammals.

Packaging, Storage & Formulations

Store at 4C in the dark.
50mM Sodium Borate
0.05% Sodium Azide
Protein G purified


Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for RBFOX3/NeuN Antibody (1B7) [DyLight 405]

  • FLJ56884
  • FLJ58356
  • Fox-1 homolog C
  • FOX3
  • FOX-3
  • hexaribonucleotide binding protein 3
  • HRNBP3
  • NeuN
  • neuronal nuclei
  • RBFOX3
  • RNA binding protein fox-1 homolog 3
  • RNA binding protein, fox-1 homolog (C. elegans) 3


RBFOX3/NeuN (RNA binding protein FOX-1 homolog 3/ Neuronal nuclei) is a RNA-binding protein localized in the nucleus as well as cytoplasm that regulates alternative splicing events. It is a member of RNA-binding FOX (RBFOX) family of splicing regulators which comprises RBFOX1 (Fox-1 or A2BP1), RBFOX2 (Fox-2 or RBM9), and RBFOX3 (Fox-3, HRNBP3, or NeuN). All of these Fox protein have single central RNA recognition motif RNA-binding domain which detects sequence (U)GCAUG observed within introns flanking alternative exons. (U)GCAUG motif position corresponding to the alternative exon dictates RBFOX's effects on splicing process. A motif localized upstream from alternative exon generally repress RBFOX-dependent exon inclusion, whereas, a downstream stream motif will usually promote inclusion. Neurons, heart, and muscle express RBFOX 1, whereas, RBFOX3 is limited to neurons only, and RBFOX2 is expressed in these tissues alongwith expression in embryos, hematopoietic cells, and embryonic stem cells. Defects in alternative splicing are known to result in neurological and neuromuscular diseases such as frontotemporal dementia and myotonic dystrophy.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for RBFOX3/NeuN Antibody (NBP1-92693V) (0)

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Secondary Antibodies


Isotype Controls

Other Available Formats

Allophycocyanin Labeled NBP1-92693APC
DyLight 350 Labeled NBP1-92693UV
DyLight 488 Labeled NBP1-92693G
DyLight 680 Labeled NBP1-92693FR
DyLight 755 Labeled NBP1-92693IR
FITC Labeled NBP1-92693F
PE Labeled NBP1-92693PE

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Bioinformatics Tool for RBFOX3/NeuN Antibody (NBP1-92693V)

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Blogs on RBFOX3/NeuN.

RBFOX3: Binding RNA, like a FOX
NeuN is a RNA-binding protein that modulates alternative splicing and is localized both to the nucleus and cytoplasm. It is a member of the RNA-binding FOX (RBFOX) family of splicing regulators which includes RBFOX1 (Fox-1/A2BP1) and RBFOX2 (Fox-2/RBM...  Read full blog post.

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Gene Symbol RBFOX3