Pellino 1 Antibody - BSA Free

Western Blot: Pellino 1 Antibody [NBP2-81888] - Analysis of Pellino 1 in human liver tissue lysate with Pellino 1 antibody at (A) 1 and (B) 2 ug/ml.

Immunocytochemistry/Immunofluorescence: Pellino 1 Antibody [NBP2-81888] - Analysis of Pellino 1 in HepG2 cells with Pellino 1 antibody at 2.5 ug/ml.

Immunocytochemistry/ Immunofluorescence: Pellino 1 Antibody - BSA Free [NBP2-81888] - Immunofluorescence of Pellino 1 in HepG2 cells with Pellino 1 antibody at 20 ug/ml.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Pellino 1 Antibody - BSA Free Summary

• Immunogen: Rabbit polyclonal Pellino 1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human Pellino 1. The immunogen is located within amino acids 300 - 350 of Pellino 1. Amino Acid Squence: CHNWGNKEERDGKDRE
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PELI1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot 1-2 ug/ml
• Theoretical MW: 46 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for Pellino 1 Antibody - BSA Free

• DKFZp686C18116
• MGC50990
• PELI1
• pellino (Drosophila) homolog 1
• pellino homolog 1 (Drosophila)
• Pellino-1
• Pellino-related intracellular-signaling molecule
• PRISM
• protein pellino homolog 1

Background

Pellino 1 is the mammalian homologue of Pellino, a Drosophila Pelle-interacting protein. Pelle is a serine-threonine kinase through which Toll signaling can occur. Pellino 1 is a scaffold protein involved in the IL-1 signaling pathway via its interaction with the complex containing IRAK kinases and TRAF6. Required for NF-kappa-B activation and IL-8 gene expression in response to IL-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PELI1