CXCL8/IL-8 Antibody (6217) [Unconjugated] Summary
E. coli-derived recombinant human IL-8/CXCL8
Ser28-Ser99 Accession # P10145
Detects human IL-8/CXCL8 in ELISAs and Western blots. In Western blots, 100% cross-reactivity with recombinant porcine IL-8/CXCL8 and no cross-reactivity with recombinant rat CXCL3/CINC-2 alpha is observed.
Details of Functionality
ActivityAssaywCitation not found None None None None None
<0.10 EU per 1 μg of the antibody by the LAL method.
Test in a species/application not listed above to receive a full credit towards a future purchase.
Western Blot 1 ug/mL CyTOF-ready ELISA Capture (Matched Antibody Pair) 2-8 ug/mL ELISA Detection (Matched Antibody Pair) 0.1-0.4 ug/mL Immunocytochemistry 8-25 ug/mL Intracellular Staining by Flow Cytometry 2.5 ug/10^6 cells Neutralization 0.08-0.4 ug/mL ELISA Standard (Matched Pair)
ELISA Detection: Human CXCL8/IL-8 Biotinylated Antibody (Catalog number BAF208)
Standard: Recombinant Human CXCL8/IL-8 (Catalog number 208-IL)
Packaging, Storage & Formulations
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Reconstitute at 0.5 mg/mL in sterile PBS.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for CXCL8/IL-8 Antibody (6217) [Unconjugated]
3-10C AMCF-I C-X-C motif chemokine 8 CXCL8 CXCL8SCYB8 Emoctakin GCP1 GCP-1TSG-1 IL8 IL-8 interleukin 8 K60 LAI LECT MDNCF MDNCFb-ENAP member 8 MONAPGCP1 NAP1 NAP-1NAP1 NCF Neutrophil-activating protein 1 Protein 3-10C T cell chemotactic factor T-cell chemotactic factor TCF TSG1 Background
CXCL8, also known as IL-8, is a CXC chemokine that is a potent chemoattractant for neutrophils and has a wide range of other pro-inflammatory effects.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
for 1 year from date of receipt.
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Publications for CXCL8/IL-8 Antibody (MAB208)(70)
We have publications tested in 6 confirmed species: Human, Bacteria - Porphyromonas gingivalis, Bovine, Complex Species Category, E. coli, Guinea Pig.
We have publications tested in 16 applications: Affinity Chromatography, Antibody Array Development, Array Development, Bioassay, ELISA Capture, ELISA Development, ELISA detection, Electrochemiluminescence, ICC, IHC Fresh, IHC Frozen, IHC Paraffin-embedded, IP, Luminex Development, Neut, WB.
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Publications using MAB208
J Ikari, AJ Nelson, J Obaid, A Giron-Mart, K Ikari, F Makino, S Iwasawa, Y Gunji, M Farid, X Wang, H Basma, D Demeo, C Feghali-Bo, O Holz, K Rabe, X Liu, SI Rennard Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease PLoS ONE, 2017;12(9):e0184039. 2017 [PMID: 28880936] (ELISA Capture,, Human) ELISA Capture
MM White, P Geraghty, E Hayes, S Cox, W Leitch, B Alfawaz, GM Lavelle, OJ McElvaney, R Flannery, J Keenan, P Meleady, M Henry, M Clynes, C Gunaratnam, NG McElvaney, EP Reeves Neutrophil Membrane Cholesterol Content is a Key Factor in Cystic Fibrosis Lung Disease EBioMedicine, 2017;23(0):173-184. 2017 [PMID: 28835336] (ELISA Capture,, Human) ELISA Capture
B Tian, A Al-Moujahe, P Bouzika, Y Hu, S Notomi, P Tsoka, JW Miller, H Lin, DG Vavvas Atorvastatin Promotes Phagocytosis and Attenuates Pro-Inflammatory Response in Human Retinal Pigment Epithelial Cells Sci Rep, 2017;7(1):2329. 2017 [PMID: 28539592] (WB,, Human) WB
Y Wang, J Liu, Q Jiang, J Deng, F Xu, X Chen, F Cheng, Y Zhang, Y Yao, Z Xia, X Xu, X Su, M Huang, L Dai, Y Yang, S Zhang, D Yu, RC Zhao, Y Wei, H Deng Human adipose-derived mesenchymal stem cell-secreted CXCL1 and CXCL8 facilitate breast tumor growth by promoting angiogenesis Stem Cells, 2017;0(0):. 2017 [PMID: 28514506] (Neut,, Human) Neut
HB Song, HO Jun, JH Kim, YH Lee, MH Choi, JH Kim Disruption of outer blood-retinal barrier by Toxoplasma gondii-infected monocytes is mediated by paracrinely activated FAK signaling PLoS ONE, 2017;12(4):e0175159. 2017 [PMID: 28406972] (Neut,, Human) Neut
Human pancreatic cancer cells induce a MyD88-dependent stromal response to promote a tumor-tolerant immune microenvironment Cancer Res., 2016;0(0):. 2016 [PMID: 27864347] (Bioassay,, Human) Bioassay
Growth Hormone Releasing Peptide-2 Attenuation of Protein Kinase C-Induced Inflammation in Human Ovarian Granulosa Cells Int J Mol Sci, 2016;17(8):. 2016 [PMID: 27548147] (WB,, Human) WB
M Hoare, Y Ito, TW Kang, MP Weekes, NJ Matheson, DA Patten, S Shetty, AJ Parry, S Menon, R Salama, R Antrobus, K Tomimatsu, W Howat, PJ Lehner, L Zender, M Narita NOTCH1 mediates a switch between two distinct secretomes during senescence Nat. Cell Biol, 2016;18(9):979-92. 2016 [PMID: 27525720] (WB,, Human) WB
Tsr Chemoreceptor Interacts With IL-8 Provoking E. coli Transmigration Across Human Lung Epithelial Cells Sci Rep, 2016;6(0):31087. 2016 [PMID: 27506372] (IP,, E. coli) IP
Z Jing, H Xu, X Chen, Q Zhong, J Huang, Y Zhang, W Guo, Z Yang, S Ding, P Chen, Z Huang The Proton-Sensing G-Protein Coupled Receptor GPR4 Promotes Angiogenesis in Head and Neck Cancer PLoS ONE, 2016;11(4):e0152789. 2016 [PMID: 27078157] (Neut,, Human) Neut
Show All 70 Publications.
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