Species: Hu, Mu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Description
Pellino 1 is the mammalian homologue of Pellino, a Drosophila Pelle-interacting protein. Pelle is a serine-threonine kinase through which Toll signaling can occur. Pellino 1 is a scaffold protein involved in the IL-1 signaling pathway via its interaction with the complex containing IRAK kinases and TRAF6. Required for NF-kappa-B activation and IL-8 gene expression in response to IL-1.
Bioinformatics
Uniprot |
Human Human Human |
Product By Gene ID |
57162 |
Alternate Names |
- DKFZp686C18116
- MGC50990
- pellino (Drosophila) homolog 1
- pellino homolog 1 (Drosophila)
- pellino-1
- Pellino-1
- Pellino-related intracellular-signaling molecule
- PRISM
- protein pellino homolog 1
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