Pellino 1 Antibody [DyLight 488]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: DyLight 488

Pellino 1 Antibody [DyLight 488] Summary

• Immunogen: Rabbit polyclonal Pellino 1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human Pellino 1. The immunogen is located within amino acids 300 - 350 of Pellino 1. Amino Acid Squence: CHNWGNKEERDGKDRE
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PELI1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Peptide affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Pellino 1 Antibody [DyLight 488]

• DKFZp686C18116
• MGC50990
• PELI1
• pellino (Drosophila) homolog 1
• pellino homolog 1 (Drosophila)
• Pellino-1
• Pellino-related intracellular-signaling molecule
• PRISM
• protein pellino homolog 1

Background

Pellino 1 is the mammalian homologue of Pellino, a Drosophila Pelle-interacting protein. Pelle is a serine-threonine kinase through which Toll signaling can occur. Pellino 1 is a scaffold protein involved in the IL-1 signaling pathway via its interaction with the complex containing IRAK kinases and TRAF6. Required for NF-kappa-B activation and IL-8 gene expression in response to IL-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PELI1