Olig1 Antibody (S07-1H5)

Western Blot: Olig1 Antibody (S07-1H5) [NBP3-19899] - Western blot detection of Olig1 in A549, HL-60, U2OS, C6 cell lysates using NBP3-19899 (1:1000 diluted). Predicted band size: 28kDa. Observed band size: 35kDa.

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: S07-1H5
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.3 mg/ml

Olig1 Antibody (S07-1H5) Summary

• Description: Novus Biologicals Rabbit Olig1 Antibody (S07-1H5) (NBP3-19899) is a recombinant monoclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthetic peptide of human Olig1 (Uniprot # Q8TAK6)
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: OLIG1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1/1000
• Theoretical MW: 35 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA
• Preservative: 0.01% Sodium Azide
• Concentration: 0.3 mg/ml
• Purity: Affinity purified

Alternate Names for Olig1 Antibody (S07-1H5)

• BHLHB6
• bHLHe21
• Class B basic helix-loop-helix protein 6
• Class E basic helix-loop-helix protein 21
• helix-loop-helix protein, class B, 6
• Olig1
• oligo1
• oligodendrocyte lineage transcription factor 1
• oligodendrocyte transcription factor 1
• oligodendrocyte-specific bHLH transcription factor 1

Background

Olig genes have been identified as the earliest known markers of oligodendrocyte lineage determination to date (Zhou et al., 2000). Olig1 is a transcription factor which promotes formation and maturation of oligodendrocytes, especially within the brain. It is expressed in the ventral spinal cord as early as 9.5 dpc and by 15.5 dpc, olig1 is dispersed throughout the gray matter. In the postnatal brain, it is present preferentially in the white matter, such as corpus callosum and cerebellar medulla. Olig1 has been demonstrated as necessary in the repair of brain lesions in patients with multiple sclerosis (Arnett et al. 2004).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: OLIG1