MBL Antibody

Images

 
There are currently no images for MBL Antibody (AF2307).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA(Cap)
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
View Available Formulations
Catalog# & Formulation Size Price

MBL Antibody Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human MBL
Glu21-Ile248
Accession # AAH96182
Specificity
Detects human MBL in ELISAs and Western blots. In sandwich ELISAs, less than 0.05% cross-reactivity with recombinant mouse (rm) MBL and rmMBL‑2 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
MBL2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.1 ug/mL
  • ELISA Capture (Matched Antibody Pair) 0.2-0.8 ug/mL
  • ELISA Detection (Matched Antibody Pair) 0.1-0.4 ug/mL
  • ELISA Standard (Matched Pair)
Application Notes
ELISA Capture:Human MBL Antibody (Catalog # AF2307)
ELISA Detection: Human MBL Biotinylated Antibody (Catalog # BAF2307)
Standard: Recombinant Human MBL (Catalog # 2307-MB)
Publications
Read Publications using
AF2307 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Purity
Immunogen affinity purified
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MBL Antibody

  • COLEC1
  • COLEC1collectin-1
  • Collectin-1
  • HSMBPC
  • Mannan-binding protein
  • mannose-binding lectin (protein C) 2, soluble (opsonic defect)
  • mannose-binding lectin (protein C) 2, soluble
  • Mannose-binding lectin
  • mannose-binding protein C
  • MBL
  • MBL2
  • MBL2D
  • MBLmannan-binding lectin
  • MBP
  • MBP1
  • MBP1mannose-binding lectin 2, soluble (opsonic defect)
  • MBP-C
  • MGC116832
  • MGC116833

Background

MBL belongs to the collectin family of innate immune defense proteins, which bind to an array of carbohydrate patterns on pathogen surfaces. MBL homotrimerizes to form a structural unit that further associates into oligomeric structures. Circulating MBL is complexed with three MBL-associated serine proteases (MASPs). Human MBL shares approximately 60% amino acid sequence identity with mouse MBL1 or MBL2.

     

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-58986
Species: Hu, Mu, Rt, Bv, Ca, Eq, GP, Ze
Applications: WB, ICC/IF, IHC
NBP1-87781
Species: Hu, Mu
Applications: WB, IHC, IHC-P
NB300-141
Species: Hu, Mu, Rt, Po, Bv, Ch, Eq, GP, Rb
Applications: WB, Simple Western, ICC/IF, IHC, IHC-Fr, IHC-P
H00004340-B01P
Species: Hu, Rt
Applications: WB
NBP2-27461
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P, PEP-ELISA
NBP1-59322
Species: Hu, Mu, Rt, Bv, Ca, Eq, Gt, GP, Rb
Applications: WB, IHC, IHC-P
AF5724
Species: Hu, Mu, Rt
Applications: WB, ICC
NB200-540
Species: Mu
Applications: Flow, IA, ICC/IF, IHC, IHC-Fr, IHC-P, IP, CyTOF-ready, Flow-IC
7954-GM/CF
Species: Hu
NBP1-88027
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, IHC-P
NBP1-85296
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
AF1724
Species: Hu
Applications: WB, IP
NBP2-42388
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P, KD

Publications for MBL Antibody (AF2307)(6)

We have publications tested in 2 confirmed species: Human, Bacteria - Moraxella catarrhalis.

We have publications tested in 5 applications: Cell Culture Treatment Control, ELISA Development, Flow Cytometry, Neutralization, Western Blot.


Filter By Application
Cell Culture Treatment Control
(1)
ELISA Development
(2)
Flow Cytometry
(1)
Neutralization
(1)
Western Blot
(1)
All Applications
Filter By Species
Human
(5)
Bacteria - Moraxella catarrhalis
(1)
All Species
Showing Publications 1 - 6 of 6.
Publications using AF2307 Applications Species
F Wang, Y Li, C Yang, Y Mu, Y Wang, W Zhang, Y Yang, C Chen, S Song, Z Shen, W Wang, J Li, J Zhai, K Guo, R Sun, L Yu, M Wang Mannan-Binding Lectin Suppresses Peptidoglycan-Induced TLR2 Activation and Inflammatory Responses Mediators Inflamm., 2019;2019(0):1349784. 2019 [PMID: 30728747] (Cell Culture Treatment Control, Human) Cell Culture Treatment Control Human
Liu G, Gradstedt H, Ermert D, Englund E, Singh B, Su Y, Johansson M, Aspberg A, Agarwal V, Riesbeck K, Blom A Moraxella catarrhalis Evades Host Innate Immunity via Targeting Cartilage Oligomeric Matrix Protein. J Immunol, 2016;196(3):1249-58. 2016 [PMID: 26712944] (Flow Cytometry, Bacteria - Moraxella catarrhalis) Flow Cytometry Bacteria - Moraxella catarrhalis
Wang M, Wang F, Yang J, Zhao D, Wang H, Shao F, Wang W, Sun R, Ling M, Zhai J, Song S Mannan-binding lectin inhibits Candida albicans-induced cellular responses in PMA-activated THP-1 cells through Toll-like receptor 2 and Toll-like receptor 4. PLoS ONE, 2013;8(12):e83517. 2013 [PMID: 24391778] (Neutralization, Human) Neutralization Human
Jusko M, Potempa J, Karim AY, Ksiazek M, Riesbeck K, Garred P, Eick S, Blom AM A metalloproteinase karilysin present in the majority of Tannerella forsythia isolates inhibits all pathways of the complement system. J. Immunol., 2012;188(5):2338-49. 2012 [PMID: 22287711] (ELISA Development, Human) ELISA Development Human
Mika A, Goh P, Holt DC Scabies mite peritrophins are potential targets of human host innate immunity. PLoS Negl Trop Dis, 2011;5(9):e1331. 2011 [PMID: 21980545] (Western Blot, Human) Western Blot Human
Skliris A, Happonen KE, Terpos E, Labropoulou V, Borset M, Heinegard D, Blom AM, Theocharis AD Serglycin inhibits the classical and lectin pathways of complement via its glycosaminoglycan chains: implications for multiple myeloma. Eur. J. Immunol., 2011;41(2):437-49. 2011 [PMID: 21268013] (ELISA Development, Human) ELISA Development Human

Reviews for MBL Antibody (AF2307) (0)

There are no reviews for MBL Antibody (AF2307). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for MBL Antibody (AF2307) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Biotin BAF2307

Additional MBL Products

Bioinformatics Tool for MBL Antibody (AF2307)

Discover related pathways, diseases and genes to MBL Antibody (AF2307). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for MBL Antibody (AF2307)

Discover more about diseases related to MBL Antibody (AF2307).
 

Pathways for MBL Antibody (AF2307)

View related products by pathway.

PTMs for MBL Antibody (AF2307)

Learn more about PTMs related to MBL Antibody (AF2307).

Blogs on MBL

There are no specific blogs for MBL, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our MBL Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol MBL2
Uniprot