Olig1 Products

Description

Olig genes have been identified as the earliest known markers of oligodendrocyte lineage determination to date (Zhou et al., 2000). Olig1 is a transcription factor which promotes formation and maturation of oligodendrocytes, especially within the brain. It is expressed in the ventral spinal cord as early as 9.5 dpc and by 15.5 dpc, olig1 is dispersed throughout the gray matter. In the postnatal brain, it is present preferentially in the white matter, such as corpus callosum and cerebellar medulla. Olig1 has been demonstrated as necessary in the repair of brain lesions in patients with multiple sclerosis (Arnett et al. 2004).

Bioinformatics

Uniprot	NP_620450 Human Q9JKN5 Mouse
Product By Gene ID	116448
Alternate Names	bHLHb6 BHLHE21 bHLHe21 Class B basic helix-loop-helix protein 6 Class E basic helix-loop-helix protein 21 helix-loop-helix protein, class B, 6 oligo1 Oligo1 oligodendrocyte lineage transcription factor 1 oligodendrocyte transcription factor 1 oligodendrocyte-specific bHLH transcription factor 1