SOX10 Antibody [Unconjugated]

Images

 
SOX10 was detected in immersion fixed BG01V human embryonic stem cells differentiated to neural crest stem cells using Goat Anti-Human SOX10 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2864) at 10 µg/mL ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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SOX10 Antibody [Unconjugated] Summary

Immunogen
E. coli-derived recombinant human SOX10
Met1-Ala118
Accession # P56693
Specificity
Detects human SOX10 in direct ELISAs and Western blots.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
SOX10
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.1 ug/mL
  • Immunocytochemistry 5-15 ug/mL
Reviewed Applications
Read 1 Review rated 5
using
AF2864 in the following applications:

Publications
Read Publications using
AF2864 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SOX10 Antibody [Unconjugated]

  • DOM
  • MGC15649
  • PCWH
  • SOX10
  • SRY (sex determining region Y)-box 10
  • SRY-related HMG-box gene 10
  • transcription factor SOX-10
  • WS4
  • WS4C
  • WS4mouse, human homolog of

Background

SOX10 belongs to the SOX family of transcription factors with diverse roles during development. In the central nervous system (CNS), SOX10 is required for the terminal differentiation of oligodendrocytes and myelination. In the peripheral nervous system, SOX10 maintains pluripotency of neural crest stem cells and suppresses neuronal differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for SOX10 Antibody (AF2864)(25)

We have publications tested in 4 confirmed species: Human, Mouse, Rat, Chicken.

We have publications tested in 9 applications: FACS, ICC, IHC, IHC-F, IHC-Fr, IHC-P, Immunoprecipitation, Proximity Ligation Assay (PLA), Western Blot.


Filter By Application
FACS
(1)
ICC
(7)
IHC
(7)
IHC-F
(1)
IHC-Fr
(4)
IHC-P
(2)
Immunoprecipitation
(1)
Proximity Ligation Assay (PLA)
(1)
Western Blot
(1)
All Applications
Filter By Species
Human
(9)
Mouse
(13)
Rat
(1)
Chicken
(1)
All Species
Showing Publications 1 - 10 of 25. Show All 25 Publications.
Publications using AF2864 Applications Species
A Tripathi, C Volsko, JP Garcia, E Agirre, KC Allan, PJ Tesar, BD Trapp, G Castelo-Br, FJ Sim, R Dutta Oligodendrocyte Intrinsic miR-27a Controls Myelination and Remyelination Cell Rep, 2019;29(4):904-919.e9. 2019 [PMID: 31644912] (IHC-P, Human) IHC-P Human
Q Wang, H Kurosaka, M Kikuchi, A Nakaya, PA Trainor, T Yamashiro Perturbed development of cranial neural crest cells in association with reduced sonic hedgehog signaling underlies the pathogenesis of retinoic-acid-induced cleft palate Dis Model Mech, 2019;12(10):. 2019 [PMID: 31591086] (IHC, Mouse) IHC Mouse
S Wiszniak, Q Schwarz Notch signalling defines dorsal root ganglia neuroglial fate choice during early neural crest cell migration BMC Neurosci, 2019;20(1):21. 2019 [PMID: 31036074] (IHC-F, Mouse) IHC-F Mouse
MSY Yeung, M Djelloul, E Steiner, S Bernard, M Salehpour, G Possnert, L Brundin, J Frisén Dynamics of oligodendrocyte generation in multiple sclerosis Nature, 2019;0(0):. 2019 [PMID: 30675058] (IHC-Fr, Human) IHC-Fr Human
A Kozlenkov, J Li, P Apontes, YL Hurd, WM Byne, EV Koonin, M Wegner, EA Mukamel, S Dracheva A unique role for DNA (hydroxy)methylation in epigenetic regulation of human inhibitory neurons Sci Adv, 2018;4(9):eaau6190. 2018 [PMID: 30263963] (FACS, Human) FACS Human
AM Lager, OG Corradin, JM Cregg, MS Elitt, HE Shick, BLL Clayton, KC Allan, HE Olsen, M Madhavan, PJ Tesar Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells Nat Commun, 2018;9(1):3708. 2018 [PMID: 30213958] (ICC, Mouse) ICC Mouse
ML Piacentino, ME Bronner Intracellular attenuation of BMP signaling via CKIP-1/Smurf1 is essential during neural crest induction PLoS Biol., 2018;16(6):e2004425. 2018 [PMID: 29949573] (IHC-P, Chicken) IHC-P Chicken
CC Winkler, OR Yabut, SP Fregoso, HG Gomez, BE Dwyer, SJ Pleasure, SJ Franco The Dorsal Wave of Neocortical Oligodendrogenesis Begins Embryonically and Requires Multiple Sources of Sonic Hedgehog J. Neurosci., 2018;0(0):. 2018 [PMID: 29739868] (IHC, Mouse) IHC Mouse
DP Kelenis, E Hart, M Edwards-Fl, JE Johnson, TY Vue ASCL1 regulates proliferation of NG2-glia in the embryonic and adult spinal cord Glia, 2018;0(0):. 2018 [PMID: 29683222] (IHC-Fr, Mouse) IHC-Fr Mouse
SY Choi, BH Bin, W Kim, E Lee, TR Lee, EG Cho Exposure of human melanocytes to UVB twice and subsequent incubation leads to cellular senescence and senescence-associated pigmentation through the prolonged p53 expression J. Dermatol. Sci., 2018;0(0):. 2018 [PMID: 29525471] (Western Blot, Human) Western Blot Human
Show All 25 Publications.

Review for SOX10 Antibody (AF2864) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Mouse.

Reviews using AF2864:
Filter by Applications
IHC-Fr
(1)
All Applications
Filter by Species
Mouse
(1)
All Species
Images Ratings Applications Species Date Details
Immunohistochemistry-Frozen SOX10 AF2864
Enlarge
reviewed by:
Anonymous
IHC-Fr Mouse 05/09/2019
View

Summary

ApplicationImmunohistochemistry-Frozen
Sample TestedEmbryonic spinal cord
SpeciesMouse
LotVRY0516091

Product General Protocols

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FAQs for SOX10 Antibody (AF2864) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Biotin BAF2864

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Bioinformatics Tool for SOX10 Antibody (AF2864)

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Recent Reviews

5
5
1
4
0
3
0
2
0
1
0

Anonymous
05/09/2019
Application: IHC-Fr
Species: Mouse

Bioinformatics

Gene Symbol SOX10
Uniprot
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