Olig2 Antibody [Unconjugated]

Olig2 and Oligodendrocyte Marker O4 were detected in 7 day differentiated rat cortical stem cells using 10 µg/mL Goat Anti-Human/Mouse/Rat Olig2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2418) and 10 µg/mL Goat Anti-Human/Mouse/Rat/Chicken O4 Monoclonal Antibody (Catalog # MAB1326). Cells were incubated with primary antibodies for 3 hours at room temperature. Cells were stained for Olig2 using the NorthernLights™ 637-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # NL002), and stained for O4 using an anti-mouse IgM secondary antibody (pseudo-stained green). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

A172 human glioblastoma cell line were fixed using formaldehyde, resuspended in lysis buffer, and sonicated to shear chromatin. Olig2/DNA complexes were immunoprecipitated using 5 μg Goat Anti-Human/Mouse/Rat Olig2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2418) or control antibody (Catalog # AB-108-C) for 15 minutes in an ultrasonic bath, followed by Biotinylated Anti-Goat IgG Secondary Antibody (Catalog # BAF109). Immunocomplexes were captured using 50 μL of MagCellect Streptavidin Ferrofluid (Catalog # MAG999) and DNA was purified using chelating resin solution. The p21 promoter was detected by standard PCR.

Olig2 was detected in immersion fixed frozen sections of mouse embryo (13 d.p.c.) using Goat Anti-Human/Mouse/Rat Olig2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2418) at 8 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to developing brain. View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.

Olig2 was detected in immersion fixed paraffin-embedded sections of human brain (cortex) using Goat Anti-Human/Mouse/Rat Olig2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2418) at 10 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cell nuclei. Staining was performed using our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

Olig2 was detected in immersion fixed paraffin-embedded sections of rat midbrain using Goat Anti-Human/Mouse/Rat Olig2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2418) at 10 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cell nuclei. Staining was performed using our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC, ChIP, ICC/IF
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

Olig2 Antibody [Unconjugated] Summary

• Immunogen: E. coli-derived recombinant human Olig2
  Met1-Lys323
  Accession # Q13516
• Specificity: Detects human Olig2 in direct ELISAs and Western blots.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: OLIG2
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Chromatin Immunoprecipitation (ChIP) 5 ug/5 x 10^6 cells
  • Immunocytochemistry 5-15 ug/mL
  • Immunohistochemistry 5-15 ug/mL
  • Western Blot 0.1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Olig2 Antibody [Unconjugated]

• BHLHB1
• BHLHE19
• Class B basic helix-loop-helix protein 1
• Class E basic helix-loop-helix protein 19
• human protein kinase C-binding protein RACK17
• Olig2
• OLIGO2
• oligodendrocyte lineage transcription factor 2
• oligodendrocyte transcription factor 2
• oligodendrocyte-specific bHLH transcription factor 2
• PRKCBP2
• protein kinase C binding protein 2
• Protein kinase C-binding protein 2
• Protein kinase C-binding protein RACK17
• RACK17
• RACK17helix-loop-helix protein, class B, 1

Background

Olig1 and Olig2 are basic-helix-loop-helix (bHLH) transcription factors expressed in the motor neuron progenitor (pMN) domain of the spinal cord that generates motor neurons and oligodendrocytes. Olig1 is involved in the development and maturation of oligodendrocytes. Olig2 is required for oligodendrocyte and motor neuron specification in the spinal cord.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Olig2 Antibody (AF2418)(98)

Publications using AF2418

• Baeza-Kallee, N;Bergès, R;Hein, V;Cabaret, S;Garcia, J;Gros, A;Tabouret, E;Tchoghandjian, A;Colin, C;Figarella-Branger, D; Deciphering the Action of Neuraminidase in Glioblastoma Models International journal of molecular sciences 2023-07-19 [PMID: 37511403] (ICC/IF, Mouse)
• Mätlik, K;Baffuto, M;Kus, L;Deshmukh, AL;Davis, DA;Paul, MR;Carroll, TS;Caron, MC;Masson, JY;Pearson, CE;Heintz, N; Cell Type Specific CAG Repeat Expansions and Toxicity of Mutant Huntingtin in Human Striatum and Cerebellum bioRxiv : the preprint server for biology 2023-06-08 [PMID: 37333326] (Flow Cytometry, Western Blot, Human)
• Maruyama, T;Tanabe, S;Uyeda, A;Suzuki, T;Muramatsu, R; Free fatty acids support oligodendrocyte survival in a mouse model of amyotrophic lateral sclerosis Frontiers in cellular neuroscience 2023-05-12 [PMID: 37252191] (IHC, Mouse)
• Seeker, LA;Bestard-Cuche, N;J�kel, S;Kazakou, NL;B�strand, SMK;Wagstaff, LJ;Cholewa-Waclaw, J;Kilpatrick, AM;Van Bruggen, D;Kabbe, M;Baldivia Pohl, F;Moslehi, Z;Henderson, NC;Vallejos, CA;La Manno, G;Castelo-Branco, G;Williams, A; Brain matters: unveiling the distinct contributions of region, age, and sex to glia diversity and�CNS function Acta neuropathologica communications 2023-05-22 [PMID: 37217978] (IHC, Human)
• Pressl, C;M�tlik, K;Kus, L;Darnell, P;Luo, JD;Weiss, AR;Liguore, W;Carroll, TS;Davis, DA;McBride, J;Heintz, N; Layer 5a Corticostriatal Projection Neurons are Selectively Vulnerable in Huntington's Disease bioRxiv : the preprint server for biology 2023-04-24 [PMID: 37162977] (ICC, Human)
• Y Wang, D Sadike, B Huang, P Li, Q Wu, N Jiang, Y Fang, G Song, L Xu, W Wang, M Xie Regulatory T cells alleviate myelin loss and cognitive dysfunction by regulating neuroinflammation and microglial pyroptosis via TLR4/MyD88/NF-kappaB pathway in LPC-induced demyelination Journal of Neuroinflammation, 2023-02-18;20(1):41. 2023-02-18 [PMID: 36803990] (IHC, Mouse)
• H Park, B Cho, H Kim, T Saito, TC Saido, KJ Won, J Kim Single-cell RNA-sequencing identifies disease-associated oligodendrocytes in male APP NL-G-F and 5XFAD mice Nature Communications, 2023-02-13;14(1):802. 2023-02-13 [PMID: 36781874] (Flow Cytometry, Mouse)
• M Ferren, A Lalande, M Iampietro, L Canus, D Decimo, D Gerlier, M Porotto, C Mathieu Early Permissiveness of Central Nervous System Cells to Measles Virus Infection Is Determined by Hyperfusogenicity and Interferon Pressure Viruses, 2023-01-13;15(1):. 2023-01-13 [PMID: 36680268] (Bioassay, Hamster - Mesocricetus auratus (Golden Hamster))
• S Chen, Y Chang, L Li, D Acosta, Y Li, Q Guo, C Wang, E Turkes, C Morrison, D Julian, ME Hester, DW Scharre, C Santiskulv, SX Song, JT Plummer, GE Serrano, TG Beach, KE Duff, Q Ma, H Fu Spatially resolved transcriptomics reveals genes associated with the vulnerability of middle temporal gyrus in Alzheimer's disease Acta neuropathologica communications, 2022-12-21;10(1):188. 2022-12-21 [PMID: 36544231] (IHC, Human)
• SI Ramos, ZM Mussa, EN Falk, B Pai, B Giotti, K Allette, P Cai, F Dekio, R Sebra, KG Beaumont, AM Tsankov, NM Tsankova An atlas of late prenatal human neurodevelopment resolved by single-nucleus transcriptomics Nature Communications, 2022-12-12;13(1):7671. 2022-12-12 [PMID: 36509746] (IHC/IF, Human)
• I Berglar, S Hehlgans, A Wehle, C Roth, C Herold-Men, F Rödel, D Kögel, B Linder CHRDL1 Regulates Stemness in Glioma Stem-like Cells Cells, 2022-12-03;11(23):. 2022-12-03 [PMID: 36497175] (Western Blot, Human)
• T Dierckx, S Vanherle, M Haidar, E Grajchen, F Mingneau, P Gervois, E Wolfs, D Bylemans, A Voet, T Nguyen, I Hamad, M Kleinewiet, JFJ Bogie, JJA Hendriks Phloretin enhances remyelination by stimulating oligodendrocyte precursor cell differentiation Proceedings of the National Academy of Sciences of the United States of America, 2022-11-07;119(46):e2120393119. 2022-11-07 [PMID: 36343243] (IHC, Mouse)
• Y Su, Y Zhou, ML Bennett, S Li, M Carceles-C, L Lu, S Huh, D Jimenez-Cy, BC Kennedy, SK Kessler, AN Viaene, I Helbig, X Gu, JE Kleinman, TM Hyde, DR Weinberger, DW Nauen, H Song, GL Ming A single-cell transcriptome atlas of glial diversity in the human hippocampus across the postnatal lifespan Cell Stem Cell, 2022-11-03;29(11):1594-1610.e8. 2022-11-03 [PMID: 36332572] (IHC, Human)
• T Zhou, Y Li, X Li, F Zeng, Y Rao, Y He, Y Wang, M Liu, D Li, Z Xu, X Zhou, S Du, F Niu, J Peng, X Mei, SJ Ji, Y Shu, W Lu, F Guo, T Wu, TF Yuan, Y Mao, B Peng Microglial debris is cleared by astrocytes via C4b-facilitated phagocytosis and degraded via RUBICON-dependent noncanonical autophagy in mice Nature Communications, 2022-10-24;13(1):6233. 2022-10-24 [PMID: 36280666] (IHC, Human)
• B Pai, J Tome-Garci, WS Cheng, G Nudelman, KG Beaumont, S Ghatan, F Panov, E Caballero, K Sarpong, L Marcuse, J Yoo, Y Jiang, A Schaefer, S Akbarian, R Sebra, D Pinto, E Zaslavsky, NM Tsankova High-resolution transcriptomics informs glial pathology in human temporal lobe epilepsy Acta neuropathologica communications, 2022-10-23;10(1):149. 2022-10-23 [PMID: 36274170] (IHC, Human)
• N Vilallongu, J Schaeffer, AM Hesse, C Delpech, B Blot, A Paccard, E Plissonnie, B Excoffier, Y Couté, S Belin, H Nawabi Guidance landscapes unveiled by quantitative proteomics to control reinnervation in adult visual system Nature Communications, 2022-10-13;13(1):6040. 2022-10-13 [PMID: 36229455] (IHC, Mouse)
• A Benraiss, JN Mariani, A Tate, PM Madsen, KM Clark, KA Welle, R Solly, L Capellano, K Bentley, D Chandler-M, SA Goldman A TCF7L2-responsive suppression of both homeostatic and compensatory remyelination in Huntington disease mice Cell Reports, 2022-08-30;40(9):111291. 2022-08-30 [PMID: 36044851] (IHC, Mouse)
• D Moezzi, Y Dong, RW Jain, BM Lozinski, S Ghorbani, C D'Mello, V Wee Yong Expression of antioxidant enzymes in lesions of multiple sclerosis and its models Scientific Reports, 2022-07-26;12(1):12761. 2022-07-26 [PMID: 35882921] (IHC, Mouse)
• Y Zhou, Y Su, S Li, BC Kennedy, DY Zhang, AM Bond, Y Sun, F Jacob, L Lu, P Hu, AN Viaene, I Helbig, SK Kessler, T Lucas, RD Salinas, X Gu, HI Chen, H Wu, JE Kleinman, TM Hyde, DW Nauen, DR Weinberger, GL Ming, H Song Molecular landscapes of human hippocampal immature neurons across lifespan Nature, 2022-07-06;0(0):. 2022-07-06 [PMID: 35794479] (IHC, Human)
• Q Liu, S Zhou, X Wang, C Gu, Q Guo, X Li, C Zhang, N Zhang, L Zhang, F Huang Apelin alleviated neuroinflammation and promoted endogenous neural stem cell proliferation and differentiation after spinal cord injury in rats Journal of Neuroinflammation, 2022-06-20;19(1):160. 2022-06-20 [PMID: 35725619] (IHC, Rat)
• A Badia-Sote, J de Vries, W Dykstra, LM Broersen, JM Verkuyl, AB Smit, MHG Verheijen High-Throughput Analysis of Astrocyte Cultures Shows Prevention of Reactive Astrogliosis by the Multi-Nutrient Combination Fortasyn Connect Cells, 2022-04-22;11(9):. 2022-04-22 [PMID: 35563732] (ICC, Mouse)
• C Azevedo, G Teku, Y Pomeshchik, JF Reyes, M Chumarina, K Russ, E Savchenko, A Hammarberg, NJ Lamas, A Collin, GK Gouras, O Klementiev, M Hallbeck, R Taipa, M Vihinen, L Roybon Parkinson's disease and multiple system atrophy patient iPSC-derived oligodendrocytes exhibit alpha-synuclein-induced changes in maturation and immune reactive properties Proceedings of the National Academy of Sciences of the United States of America, 2022-03-16;119(12):e2111405119. 2022-03-16 [PMID: 35294277] (ICC, IHC, Human)
• T Feng, L Luan, II Katz, M Ullah, VM Van Deerli, JQ Trojanowsk, EB Lee, F Hu TMEM106B deficiency impairs cerebellar myelination and synaptic integrity with Purkinje cell loss Acta neuropathologica communications, 2022-03-14;10(1):33. 2022-03-14 [PMID: 35287730] (Western Blot, Mouse)
• T Xu, X Li, Y Guo, E Uhlin, L Holmberg, S Mitra, D Winn, A Falk, E Sundström Multiple therapeutic effects of human neural stem cells derived from induced pluripotent stem cells in a rat model of post-traumatic syringomyelia EBioMedicine, 2022-02-16;77(0):103882. 2022-02-16 [PMID: 35182996] (ICC, Human)
• C Ogawa, S Mikawa, S Li, Y Hayashi, K Masumoto, K Sato BMP10 expression in the adult rat central nervous system Journal of chemical neuroanatomy, 2022-02-16;121(0):102084. 2022-02-16 [PMID: 35182716] (IHC, Rat)
• W Wang, H Cho, JW Lee, SK Lee The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development Nature Communications, 2022-02-17;13(1):958. 2022-02-17 [PMID: 35177643] (IHC, Mouse)
• BD Needham, M Funabashi, MD Adame, Z Wang, JC Boktor, J Haney, WL Wu, C Rabut, MS Ladinsky, SJ Hwang, Y Guo, Q Zhu, JA Griffiths, R Knight, PJ Bjorkman, MG Shapiro, DH Geschwind, DP Holschneid, MA Fischbach, SK Mazmanian A gut-derived metabolite alters brain activity and anxiety behaviour in mice Nature, 2022-02-14;602(7898):647-653. 2022-02-14 [PMID: 35165440] (IHC, Mouse)
• D Almansa, H Peinado, R García-Rod, Á Casadomé-P, CG Dotti, FX Guix Extracellular Vesicles Derived from Young Neural Cultures Attenuate Astrocytic Reactivity In Vitro International Journal of Molecular Sciences, 2022-01-25;23(3):. 2022-01-25 [PMID: 35163295] (ICC, Rat)
• Q Wu, Y Shichino, T Abe, T Suetsugu, A Omori, H Kiyonari, S Iwasaki, F Matsuzaki Selective translation of epigenetic modifiers affects the temporal pattern and differentiation of neural stem cells Nature Communications, 2022-01-25;13(1):470. 2022-01-25 [PMID: 35078993] (IHC, Mouse)
• WU Park, GB Yeon, MS Yu, HG Goo, SH Hwang, D Na, DS Kim A Novel Vitronectin Peptide Facilitates Differentiation of Oligodendrocytes from Human Pluripotent Stem Cells (Synthetic ECM for Oligodendrocyte Differentiation) Biology, 2021-12-01;10(12):. 2021-12-01 [PMID: 34943169] (ICC, Human)
• LM Toomey, M Papini, B Lins, AJ Wright, A Warnock, T McGonigle, SC Hellewell, CA Bartlett, C Anyaegbu, M Fitzgerald Cuprizone feed formulation influences the extent of demyelinating disease pathology Scientific Reports, 2021-11-19;11(1):22594. 2021-11-19 [PMID: 34799634] (IHC, Mouse)
• Y Kimura, Y Hayashi, S Hitomi, D Ikutame, K Urata, I Shibuta, A Sakai, J Ni, K Iwata, M Tonogi, M Shinoda IL-33 induces orofacial neuropathic pain through Fyn-dependent phosphorylation of GluN2B in the trigeminal spinal nucleus caudalis Brain, Behavior, and Immunity, 2021-10-26;0(0):. 2021-10-26 [PMID: 34715301] (IHC, Mouse)
• Y Takanezawa, S Tanabe, D Kato, R Ozeki, M Komoda, T Suzuki, H Baba, R Muramatsu Microglial ASD-related genes are involved in oligodendrocyte differentiation Scientific Reports, 2021-09-08;11(1):17825. 2021-09-08 [PMID: 34497307] (IHC, Mouse)
• LE Blizzard, C Menke, SD Patel, RR Waclaw, SA Lachke, RW Stottmann A Novel Mutation in Cse1l Disrupts Brain and Eye Development with Specific Effects on Pax6 Expression Journal of developmental biology, 2021-07-07;9(3):. 2021-07-07 [PMID: 34287339] (IHC, Mouse)
• M Connor, K Lamorie-Fo, Q Liu, K Shkirkova, H Baertsch, C Sioutas, TE Morgan, CE Finch, WJ Mack Nanoparticulate matter exposure results in white matter damage and an inflammatory microglial response in an experimental murine model PLoS ONE, 2021-07-02;16(7):e0253766. 2021-07-02 [PMID: 34214084] (IHC, Mouse)
• T Zhang, T Liu, N Mora, J Guegan, M Bertrand, X Contreras, AH Hansen, C Streicher, M Anderle, N Danda, L Tiberi, S Hippenmeye, BA Hassan Generation of excitatory and inhibitory neurons from common progenitors via Notch signaling in the cerebellum Cell Reports, 2021-06-08;35(10):109208. 2021-06-08 [PMID: 34107249] (IHC, Mouse)
• SM Nam, JH Choi, SH Choi, HJ Cho, YJ Cho, H Rhim, HC Kim, IH Cho, DG Kim, SY Nah Ginseng gintonin alleviates neurological symptoms in the G93A-SOD1 transgenic mouse model of amyotrophic lateral sclerosis through lysophosphatidic acid 1 receptor Journal of Ginseng Research, 2020-05-01;45(3):390-400. 2020-05-01 [PMID: 34025132] (IHC, Mouse)
• P Filppu, JT Ramanathan, KJ Granberg, E Gucciardo, H Haapasalo, K Lehti, M Nykter, V Le Joncour, P Laakkonen CD109-GP130 interaction drives glioblastoma stem cell plasticity and chemoresistance through STAT3 activity JCI Insight, 2021-05-10;6(9):. 2021-05-10 [PMID: 33986188] (Co-Immunoprecipitation, IHC, Western Blot, Human)
• W Mu, S Li, J Xu, X Guo, H Wu, Z Chen, L Qiao, G Helfer, F Lu, C Liu, QF Wu Hypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice Nature Communications, 2021-04-16;12(1):2288. 2021-04-16 [PMID: 33863883] (IHC, Mouse)
• JE Lee, S Ahn, H Jeong, S An, CH Myung, JA Lee, SC Hong, YJ Kim, JY Kim, JH Ryu, M Noh, KT Nam, JS Hwang Olig2 regulates p53-mediated apoptosis, migration and invasion of melanoma cells Scientific Reports, 2021-04-08;11(1):7778. 2021-04-08 [PMID: 33833342] (IHC, Western Blot, Human)
• Y Dong, C D'Mello, W Pinsky, BM Lozinski, DK Kaushik, S Ghorbani, D Moezzi, D Brown, FC Melo, S Zandee, T Vo, A Prat, SN Whitehead, VW Yong Oxidized phosphatidylcholines found in multiple sclerosis lesions mediate neurodegeneration and are neutralized by microglia Nature Neuroscience, 2021-02-18;0(0):. 2021-02-18 [PMID: 33603230] (IHC, Mouse)
• C Ogawa, S Mikawa, Y Hayashi, K Masumoto, F Katou, K Sato BMP9 expression in the adult rat brain Journal of chemical neuroanatomy, 2021-02-11;113(0):101933. 2021-02-11 [PMID: 33582251] (IHC, Rat)
• L Poh, DY Fann, P Wong, HM Lim, SL Foo, SW Kang, V Rajeev, S Selvaraji, VR Iyer, N Parathy, MB Khan, DC Hess, DG Jo, GR Drummond, CG Sobey, MKP Lai, CL Chen, LHK Lim, TV Arumugam AIM2 inflammasome mediates hallmark neuropathological alterations and cognitive impairment in a mouse model of vascular dementia Molecular Psychiatry, 2020-12-09;0(0):. 2020-12-09 [PMID: 33299135] (IHC, Mouse)
• W Tao, A Zhang, K Zhai, Z Huang, H Huang, W Zhou, Q Huang, X Fang, BC Prager, X Wang, Q Wu, AE Sloan, MS Ahluwalia, JD Lathia, JS Yu, JN Rich, S Bao SATB2 drives glioblastoma growth by recruiting CBP to promote FOXM1 expression in glioma stem cells EMBO Mol Med, 2020-10-30;0(0):e12291. 2020-10-30 [PMID: 33124191] (IHC, Human, Mouse)
• BY Fan, YL Pang, WX Li, CX Zhao, Y Zhang, X Wang, GZ Ning, XH Kong, C Liu, X Yao, SQ Feng Liproxstatin-1 is an effective inhibitor of oligodendrocyte ferroptosis induced by inhibition of glutathione peroxidase 4 Neural regeneration research, 2021-03-01;16(3):561-566. 2021-03-01 [PMID: 32985488] (ICC, Human)
• AL Koessinger, D Koessinger, K Stevenson, C Cloix, L Mitchell, C Nixon, N Gomez-Roma, AJ Chalmers, JC Norman, SWG Tait Quantitative in vivo bioluminescence imaging of orthotopic patient-derived glioblastoma xenografts Scientific Reports, 2020-09-21;10(1):15361. 2020-09-21 [PMID: 32958777] (Western Blot, Human)
• W Wang, H Cho, D Kim, Y Park, JH Moon, SJ Lim, SM Yoon, M McCane, SA Aicher, S Kim, B Emery, JW Lee, S Lee, Y Park, SK Lee PRC2 Acts as a Critical Timer That Drives Oligodendrocyte Fate over Astrocyte Identity by Repressing the Notch Pathway Cell Rep, 2020-09-15;32(11):108147. 2020-09-15 [PMID: 32937136] (IHC, Chicken, Mouse)
• MJ Borrett, BT Innes, D Jeong, N Tahmasian, MA Storer, GD Bader, DR Kaplan, FD Miller Single-Cell Profiling Shows Murine Forebrain Neural Stem Cells Reacquire a Developmental State when Activated for Adult Neurogenesis Cell Rep, 2020-08-11;32(6):108022. 2020-08-11 [PMID: 32783944] (FISH, IHC, Mouse, Transgenic Mouse)
• S Kaji, T Maki, J Ueda, T Ishimoto, Y Inoue, K Yasuda, M Sawamura, R Hikawa, T Ayaki, H Yamakado, R Takahashi BCAS1-positive immature oligodendrocytes are affected by the &alpha-synuclein-induced pathology of multiple system atrophy Acta Neuropathol Commun, 2020-07-29;8(1):120. 2020-07-29 [PMID: 32727582] (IHC, Rat)
• M Duman, A Vaquié, G Nocera, M Heller, M Stumpe, D Siva Sanka, J Dengjel, D Meijer, T Yamaguchi, P Matthias, T Zeis, N Schaeren-W, A Hayoz, S Ruff, C Jacob EEF1A1 deacetylation enables transcriptional activation of remyelination Nat Commun, 2020-07-09;11(1):3420. 2020-07-09 [PMID: 32647127] (ICC, IHC, Mouse)
• LM Ruiz-Perer, JFW Greiner, C Kaltschmid, B Kaltschmid A Matter of Choice: Inhibition of c-Rel Shifts Neuronal to Oligodendroglial Fate in Human Stem Cells Cells, 2020-04-22;9(4):. 2020-04-22 [PMID: 32331232] (ICC, Human)
• TC Ma, KI Vong, KM Kwan Spatiotemporal Decline of BMP Signaling Activity in Neural Progenitors Mediates Fate Transition and Safeguards Neurogenesis Cell Rep, 2020-03-17;30(11):3616-3624.e4. 2020-03-17 [PMID: 32187534] (IHC, Mouse)
• SM Nam, SH Choi, HJ Cho, JS Seo, M Choi, SS Nahm, BJ Chang, SY Nah Ginseng Gintonin Attenuates Lead-Induced Rat Cerebellar Impairments during Gestation and Lactation Biomolecules, 2020-03-02;10(3):. 2020-03-02 [PMID: 32131481] (IHC, Rat)
• M Fares, M Cochet-Ber, G Gonzalez, CN Montero-Me, O Blanchet, A Benchoua, C Boissart, S Lecollinet, J Richardson, N Haddad, M Coulpier Pathological modeling of TBEV infection reveals differential innate immune responses in human neurons and astrocytes that correlate with their susceptibility to infection J Neuroinflammation, 2020-03-03;17(1):76. 2020-03-03 [PMID: 32127025] (ICC, Human)
• C Ogawa, S Mikawa, K Yamashita, Y Hayashi, K Masumoto, F Katou, K Sato Follistatin expression in the central nervous system of the adult rat J. Chem. Neuroanat., 2020-01-31;105(0):101753. 2020-01-31 [PMID: 32014555] (IHC, Rat)
• Y Zhou, WM Song, PS Andhey, A Swain, T Levy, KR Miller, PL Poliani, M Cominelli, S Grover, S Gilfillan, M Cella, TK Ulland, K Zaitsev, A Miyashita, T Ikeuchi, M Sainouchi, A Kakita, DA Bennett, JA Schneider, MR Nichols, SA Beausoleil, JD Ulrich, DM Holtzman, MN Artyomov, M Colonna Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease Nat. Med., 2020-01-13;26(1):131-142. 2020-01-13 [PMID: 31932797] (IHC, Mouse)
• LM Toomey, CA Bartlett, N Gavriel, T McGonigle, M Majimbi, G Gopalasing, J Rodger, M Fitzgerald Comparing modes of delivery of a combination of ion channel inhibitors for limiting secondary degeneration following partial optic nerve transection Sci Rep, 2019-10-25;9(1):15297. 2019-10-25 [PMID: 31653948] (IHC, Rat)
• S Clavreul, L Abdeladim, E Hernández-, D Niculescu, J Durand, SH Ieng, R Barry, G Bonvento, E Beaurepair, J Livet, K Loulier Cortical astrocytes develop in a plastic manner at both clonal and cellular levels Nat Commun, 2019-10-25;10(1):4884. 2019-10-25 [PMID: 31653848] (IHC, Mouse)
• M Boström, Y Eriksson, J Danial, T Björk-Erik, M Kalm Chronic disturbance in the thalamus following cranial irradiation to the developing mouse brain Sci Rep, 2019-07-03;9(1):9588. 2019-07-03 [PMID: 31270437] (IHC, Mouse)
• G Gopalasing, CA Bartlett, T McGonigle, M Majimbi, A Warnock, A Ford, A Gough, LM Toomey, M Fitzgerald The effects of a combination of ion channel inhibitors on pathology in a model of demyelinating disease Mult Scler Relat Disord, 2019-06-08;34(0):1-8. 2019-06-08 [PMID: 31202958] (IHC, Mouse)
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Reviews for Olig2 Antibody (AF2418) (2)

Average Rating: 4.5

(Based on 2 reviews)

We have 2 reviews tested in 1 species: Mouse.

reviewed by: Xuecheng Qiu IHC-Fr Mouse 05/12/2019

Summary

• Application: Immunohistochemistry-Frozen
• Sample Tested: Mouse brain
• Species: Mouse
• Lot: UPA0617051

reviewed by: Verified Customer ICC Mouse 01/06/2015

Summary

• Application: Immunocytochemistry
• Sample Tested: See PMID 22504067
• Species: Mouse

Bioinformatics

• Gene Symbol: OLIG2
• Uniprot:
  • Q13516()