Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.02% Sodium Azide
Peptide affinity purified
Alternate Names for Nephrin Antibody
nephrosis 1, congenital, Finnish type (nephrin)
Renal glomerulus-specific cell adhesion receptor
Nephrin is strongly expressed in renal glomeruli and is a member of the immunoglobulin family of cell adhesion molecules. Mutations in the Nephrin gene result in congenital nephrotic syndrome, an autosomal-recessive disorder characterized by massive proteinuria in utero and nephrosis at birth. Renal glomeruli allow normal kidneys to filter plasma so that it is very pure. Nephrin is expressed in the podocyte slit-diaphragm of the renal glomeruli in a manner that suggests that Nephrin molecules homodimerize in an anti-parallel fashion similar to cadherin interactions in adherens junctions. Thus, Nephrin may constitute the entire extracellular structure of the slit-diaphragm. Despite its predicted molecular weight, Nephrin often migrates at a lower than expected size in SDS-PAGE.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
FAQs for Nephrin Antibody (NBP1-77303). (Showing 1 - 1 of 1 FAQs).
I was reviewing the datasheet for product, NBP177303 (anti-Nephrin Ab) and I did not see any antigen retrieval information. Could you please let me know what is required for antigen retrieval?
There are no special instructions for this antibody and, therefore, none are recommended on the website. We recommend that you proceed with your usual protocol. Here is a link to our general protocols and they just need to be optimized. http://www.novusbio.com/support/support-by-application/immunohistochemistry-paraffin/protocol.html
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.
Review this Product
Be the first to review our Nephrin Antibody and receive a gift card or discount.