Biological Strategies: Western Blot: Synaptopodin Antibody [NBP2-39100] - Representative western blotting results of nephrin and synaptopodin expression level in cultured podocytes as indicates. Image collected ...read more
Immunocytochemistry/ Immunofluorescence: Synaptopodin Antibody [NBP2-39100] - Mouse brain tissue with SYNPO antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: Synaptopodin Antibody [NBP2-39100] - Human brain tissue with SYNPO antibody at 2.5 ug/mL.
Western Blot: Synaptopodin Antibody [NBP2-39100] - Analysis of SYNPO in rat brain tissue lysate with SYNPO antibody at (A) 1 and (B) 2 ug/mL.
Immunocytochemistry/ Immunofluorescence: Synaptopodin Antibody [NBP2-39100] - Human brain tissue with SYNPO antibody at 20 ug/mL.
Immunohistochemistry: Synaptopodin Antibody [NBP2-39100] - Mouse brain tissue with SYNPO antibody at 5 ug/mL.
Antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human SYNPO. The immunogen is located within the last 50 amino acids of SYNPO. Amino Acid Squence: SPSRAWSPRAKQAPRPS
At least three isoforms of SYNPO are known to exist; this antibody will detect all three isoforms. SYNPO antibody is predicted to not cross-react with other SYNPO family member proteins.
Peptide affinity purified
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95 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.02% Sodium Azide
Peptide affinity purified
Alternate Names for Synaptopodin Antibody - BSA Free
SYNPO, also known as synaptopodin, is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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