This product is unpurified. The exact concentration of antibody is not quantifiable.
This MRP1 antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot analysis on transfected lysate, where a band is seen at ~172 kDa. The use of this antibody in ICC/IF was reported in literature. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Read Publication using NB110-57131 in the following applications:
Immunogen has 96% homology to rat, primate, and feline, 88% homology to chicken, 87% homology to bovine, 72% homology to Drosophila melanogaster.
Alternate Names for MRP1 Antibody (IU5C1)
ATP-binding cassette sub-family C member 1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
Leukotriene C(4) transporter
multidrug resistance associated protein 1
multidrug resistance protein
multidrug resistance-associated protein 1
multiple drug resistance protein 1
multiple drug resistance-associated protein
The MRP molecule, an integral membrane glycophosphoprotein belonging to the same superfamily of ATP-binding cassette transmembrane transporter proteins as P-glycoprotein, is overexpressed in many P-glycoprotein-negative, multidrug resistant cell lines and tumours. It is believed that the main function of MRP in drug resistance is that of a plasma membrane drug efflux pump.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.