mGluR3 Antibody

Images

 
Immunohistochemistry-Paraffin: mGluR3 Antibody [NLS3208] - Anti-GRM3 / MGLUR3 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen ...read more
Immunohistochemistry-Paraffin: mGluR3 Antibody [NLS3208] - Analysis of anti-GRM3 / MGLUR3 antibody with transfection control.
Immunohistochemistry-Paraffin: mGluR3 Antibody [NLS3208] - Analysis of anti-GRM3 / MGLUR3 antibody with HEK293 human embryonic kidney cells transfected with GRM3 / MGLUR3.
Immunohistochemistry-Paraffin: mGluR3 Antibody [NLS3208] - Analysis of anti-GRM3 / MGLUR3 antibody with human brain, coroid plexus at 38 ug/ml.
Immunohistochemistry-Paraffin: mGluR3 Antibody [NLS3208] - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunohistochemistry-Paraffin: mGluR3 Antibody [NLS3208] - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunohistochemistry-Paraffin: mGluR3 Antibody [NLS3208] - Anti-GRM3 / MGLUR3 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Product Details

Summary
Reactivity Hu, Po, Bv, Eq, Mk, Pm, Mu, Rt, Op, RbSpecies Glossary
Applications WB, IHC-P, ICC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

mGluR3 Antibody Summary

Immunogen
Synthetic 16 amino acid peptide from N-terminal extracellular domain of human GRM3 / MGLUR3.
Epitope
N-terminal extracellular domain of human
Specificity
Human GRM3 / MGLUR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Mouse (94%), Rat (94%), Opossum (100%), Rabbit (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GRM3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100 - 1:2000
  • Immunohistochemistry-Paraffin 38 ug/ml
  • Immunocytochemistry 1:10 - 1:500

Reactivity Notes

Gorilla, Orangutan, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Elephant (100%), Panda (100%), Turkey (81%), Chicken (81%), Xenopus (81%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for mGluR3 Antibody

  • GLUR3
  • glutamate receptor, metabotropic 3
  • GPRC1C
  • GPRC1Cglutamate metabotropic receptor 3
  • GRM3
  • mGlu3
  • mGluR3
  • MGLUR3metabotropic glutamate receptor 3

Background

The Metabotropic Glutamate Receptor GRM3 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. Metabotropic glutamate receptor Group II includes the GRM2 and GRM3 receptors that are linked to inhibition of the cyclic AMP signaling cascade. GRM3 has been reported in various regions of the brain and spinal cord. ESTs have been isolated from brain, embryo, fetal lung/testis/B-cell, nerve, placenta, prostate, and vessel libraries. Caution: GLUR3 refers to Ionotropic Glutamate Receptor 3, not to Metabotropic Glutamate Receptor 3 (mGLUR3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GRM3
Entrez