mGluR3 Antibody (SR1543) - BSA Free

Western Blot: mGluR3 Antibody (SR1543) [NBP3-22382] - Western blot analysis using NBP3-22382 in Human cerebellum lysate.

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: SR1543
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

mGluR3 Antibody (SR1543) - BSA Free Summary

• Description: Novus Biologicals Rabbit mGluR3 Antibody (SR1543) - BSA Free (NBP3-22382) is a recombinant monoclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human mGluR3 (Uniprot #: Q14832)
• Specificity: Detects endogenous levels of total mGluR3
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: GRM3
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:2000
• Theoretical MW: 330 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for mGluR3 Antibody (SR1543) - BSA Free

• GLUR3
• glutamate receptor, metabotropic 3
• GPRC1C
• GPRC1Cglutamate metabotropic receptor 3
• GRM3
• mGlu3
• mGluR3
• MGLUR3metabotropic glutamate receptor 3

Background

The Metabotropic Glutamate Receptor GRM3 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. Metabotropic glutamate receptor Group II includes the GRM2 and GRM3 receptors that are linked to inhibition of the cyclic AMP signaling cascade. GRM3 has been reported in various regions of the brain and spinal cord. ESTs have been isolated from brain, embryo, fetal lung/testis/B-cell, nerve, placenta, prostate, and vessel libraries. Caution: GLUR3 refers to Ionotropic Glutamate Receptor 3, not to Metabotropic Glutamate Receptor 3 (mGLUR3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GRM3