MCAM/CD146 Antibody (MUC18/1130) [DyLight 680]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, ICC/IF, IHC, IHC-P
Clone
MUC18/1130
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 680

Order Details

MCAM/CD146 Antibody (MUC18/1130) [DyLight 680] Summary

Immunogen
Recombinant full-length human MCAM/CD146 protein
Localization
Cell surface
Specificity
The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MCAM
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MCAM/CD146 Antibody (MUC18/1130) [DyLight 680]

  • CD146 antigen
  • CD146
  • cell surface glycoprotein MUC18
  • Cell surface glycoprotein P1H12
  • L-Gicerin
  • MCAM
  • melanoma adhesion molecule
  • melanoma cell adhesion moleculeS-endo 1 endothelial-associated antigen
  • Melanoma-associated antigen A32
  • Melanoma-associated antigen MUC18
  • MUC18
  • MUC18Gicerin

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for MCAM/CD146 Antibody (NBP2-47777FR) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47777AF350
Alexa Fluor 405 NBP2-47777AF405
Alexa Fluor 488 NBP2-47777AF488
Alexa Fluor 532 NBP2-47777AF532
Alexa Fluor 594 NBP2-47777AF594
Alexa Fluor 647 NBP2-47777AF647
Alexa Fluor 700 NBP2-47777AF700
Alexa Fluor 750 NBP2-47777AF750
Allophycocyanin NBP2-47777APC
Allophycocyanin/Cy7 NBP2-47777APCCY7
Biotin NBP2-47777B
DyLight 350 NBP2-47777UV
DyLight 405 NBP2-47777V
DyLight 488 NBP2-47777G
DyLight 550 NBP2-47777R
DyLight 594 NBP2-47777DL594
DyLight 650 NBP2-47777C
DyLight 680 NBP2-47777FR
DyLight 755 NBP2-47777IR
FITC NBP2-47777F
HRP NBP2-47777H
Janelia Fluor 549 NBP2-47777JF549
Janelia Fluor 646 NBP2-47777JF646
PE NBP2-47777PE
PE/Atto594 NBP2-47777PEATT594
PE/Cy5.5 NBP2-47777PECY55
PE/Cy7 NBP2-47777PECY7
PerCP NBP2-47777PCP

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Bioinformatics Tool for MCAM/CD146 Antibody (NBP2-47777FR)

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Bioinformatics

Gene Symbol MCAM